I agree with those who have experienced no visible results whatsoever with this product. I agree completely with Jeanne's review EXCEPT I'm in my mid-30s and the product did nothing for me. So now others have reviews from several age groups. I would encourage others to maybe try something else before plopping down the $110 on BioEffect. Sorry!

While I liked that I never felt greasy and that the serum is definitively smooth and silky in its consistency, I also wanted more bang for my buck… as in more radiance, less wrinkles and that healthy “glow” of feeling like I’d turned back time. The reality: Four weeks into my new serum routine, I didn’t see any noticeable changes.

The bottom line: There’s a lot of hype to the serum – sort of like the buzz around the Oscar-nominated Best Pictures – and then you go to the movies and say “Really?” because you had such high expectations and can’t help but be slightly disappointed. All of which is my longwinded way of saying you can take this review with a grain of salt. My opinion is that this serum probably works best for those in their 30s and 40s than for those in their 50s and 60s.

I really like this serum. And, actually, like it more that ReLuma, which was my favorite in the past. I haven’t used it for a long time yet, only about 10 days, but have already noticed some improvements on my skin. First of all it calms my skin, on the contrary from some people who stated that it broke them out. I put 2 drops every night over entire face after washing it. This serum is very light, not at all sticky and absorbs almost instantly. My skin feels “happy” after I put it on in the evening and looks perfectly hydrated, toned and moisturized in the morning. I was not expecting any noticeable changes after such short time, but I noticed after a week that lines on my forehead and around the mouth are much lighter, my sensitive skin is calmer and more toned. So for me it really works nicely. I’ll keep using it and see what happens.

I really like this product. There is nothing not to like. First - the texture is amazing and very little goes a long way - it distributes well over large area. Yes, it takes time and patience with this little guy, but after 3 weeks I saw noticeable results - stubborn wrinkles have diminished in appearance, skin smoothed out and fine wrinkles have disappeared. I use it in cycles - 3 weeks, then give it a 2 weeks rest, then apply for another 3 weeks.

I used the serum for four weeks and, unfortunately, did not notice any difference in my skin other than one pretty serious blemish. I wouldn’t dissuade anyone else from trying this product as others have had excellent results from it. For me, however, I guess the search continues!

After fantastic results with the ReLuma Skin Illuminating Serum and several other TIA-recommended products, I thought this might be the new holy grail of anti-aging. I jumped in enthusiastically and followed the instructions to a T. In the end, I think my results were mixed with some things I liked about the product and some not so much. I didn’t have an irritated, flare-up reaction to this product, but more like a pimple or two in different spots because the product was just too rich. I suspect that Bioeffect is a powerful serum that works better on somewhat older skin (I’m 43) that has diminished growth factors, while my wrinkles are more the product of years of squinting at the bright California sun.

After 6 weeks of using this on my crows-feet, I whole-heartedly agree with your review Marta!! It think it's oilier than I remember E'shee being and the smallest amount spreads easily. I spot treated crows feet, lines above my mouth and between my brows. REALLY pleased with the results on my crows feet, but oddly, it hasn't done anything for the lines above my lips. I had to stop using it between my brows as it broke me out.