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* A dipeptide consisting of the standard amino acids valine and tryptophan.
Mainly works as a skin conditioning agent. It's also believed to improve lymphatic circulation, and for this reason is often used in eye creams aiming to combat dark and puffy under-eye circles. Many cosmtic manufacturers market it as clinically proven to reduce under-eye bagginess and puffiness, however, it's difficult to find any published (and unbiased) "clinical" data supporting such claims.
Yet, putting all questions surrounding the validity of such de-puffing claims aside, the amino acid structure of this ingredient does make it an effective skin conditioner. Because its structure resembles that of the lipid content of of the epidermis, it's considered to be a Natural Moisturizing Factor (NMF). As an NMF, it helps keep the intercellular structure of the epidermis intact, facilitates the skin’s healing process, prevents dermal irritation and may even regenerate the skin. In fact, several animal studies suggest that the topical application of dipeptide-2 may act as a growth promoter because of its ability to increase the skin's protein synthesis and amino acid uptake. You can find this ingredient in a variety of cosmetic products such as eye cream, anti-aging treatment, facial moisturizer/lotion, sunscreen, body lotion and eye makeup.
Recommended Products w/ dipeptide-2:
Hydropteptide Eye Extreme Dark Circle Concentrate ($69.99), Derma Radiant Ageless Eyes ($39), MD Skincare Lift & LIghten Eye Cream ($150)