I have finally got around to trying Cellbone Hyper-Peptides ($76) after is was recommended by Anamarie in a comment on our Five Best with Matrixyl post. With its roll call of who's who's in designer peptides, this is one impressive serum and after only a week of using it (on one side of my face while I test Hydropeptide Serum on the other), I can report tighter, firmer and plumper skin. Although it is early days, I think I can already see it having an effect on those stubborn forehead and marionette lines.

Certainly, using Cellbone Hyper-Peptides is an enjoyable experience (especially after my unpleasant one with Neocutis). The yellowish liquid is easily dispensed from the faux medical looking bottle, complete with squeeze dropper, soaks in easily and doesn't leave any sticky residue. And, so far, I've had no adverse reactions.

It isn't surprising that I've noticed a tighter feeling: Cellbone Hyperpeptides has most of the 'Botox in a jar' products known to man. These neuropetides claim to fight against expression lines, preventing future wrinkles by temporarily debilitating the muscle, keeping it from contracting and thereby smoothing lines in the wrinkle prone area. Argireline is well known as the peptide that stops facial muscles from moving and causing expression lines. Although there are studies that show that a 10% concentration over 30 days can reduce the appearance of wrinkles by 30%, some cosmetologists seem to think that Argireline would be most effective at concentrations as high as 25%. I mention this because it is the second ingredient in Cellbone Hyper-Peptides after water. Still, Cellbone seems to be hedging its bets by including SNAP-8, created by Kinerase, is being marketed as the second generation of Argireline, and is said to be 30% more effective. Then there is Syn-ake, supposedly a mimicer of snake venom.

While all these neuropeptides are supposedly stopping the formation of new wrinkles and the deepening of existing ones, Matrixyl 3000 is boosting the formation of new collagen.  Gotu kola (centella asiatica), idebenone and bilberry are providing the antioxidant role. Then there are several alpha hydroxy acids - cane and maple sugars and citrus fruit extracts.

In a way, Cellbone has put together most of the things you would want from a serum that prevents wrinkles and may even repair existing skin damage. But I can't help wondering if all those face freezers are really necessary. I am very interested to see how this performs over the coming weeks. And I will, of course, report back.

Ingredients: Water, Acetyl Hexapeptide-3 (Argireline®), Acetyl Glutamyl Heptapeptide-1 (SNAP-8), Palmitoyl Pentapeptide-3, Tripeptide (SYN®-AKE), Palmitoyl Oligopeptide & Terapeptide-3 (Matrixyl®-3000), Dimethyl Isosorbide, Butyleneglycol, Glycerin, Willow Bark Extract, Bilberry Extract, Sugar Cane Extract, Sugar Maple Extract, Orange Fruit Extract, Lemon Extract, Sodium Lactate, Panthenol, Cucumber Flower Extract, Phenoxyethanol, Sodium Hyaluronate, Centella Asiatica Extract, Idebenone, Alpha Tocopherol, Menthol