I was given a clutch of Neova products the other day and, since I'm not big on night creams, I'm offering up a free jar of Neova Night Therapy ($74 for 1.7oz) to whomever is willing to review it for us. Just post a comment saying why you'd like to give a go and promise faithfully that you'll send in your feedback.

My take on Neova Night Therapy is that it is a gourmet sandwich filling in between slices of mediocre grocery store bread. The standout ingredient is copper peptide, but not just any old one. When you combine copper with a GHK protein peptide (GHK-CU), something pretty impressive happens. One study performed on 20 people showed that, after 30 days, the formation of pro-collagen (a precursor of collagen) increased by 70% (shown by skin biopsy) compared with 50% from vitamin C and 40% due to tretinoin (vitamin A).

A peptide naturally found in human skin and tissue, GHK (glycyl-L-histidyl-L-lysine), binds copper molecules, allowing them to arrive in an active state where needed. This peptide is now chemically synthesized and is known as prezatide copper acetate. This is used by Neova. You won't find this GHK form of copper peptides very often (due, as far as I can work out, to closely held patents). In addition to Procyte (Neova's parent), Skin Biology and Neutrogena are the only potion makers that I know of that us it.

The Copper tripeptide in Neutrogena is a 1:1 ratio of the GHK molecule to copper and the prezatide copper acetate in Neova products is a 2:1 ratio of GHK to copper. In addition, Neova Night Therapy has sodium carboxymethyl betaglucan (another wound healer), camellia oleifera (tea), vitamin E, sodium hyaluranate, squalane, grape and apricot kernel. The rest is made up of emollients, silicones and the usual suspects from preservative land.

Ingredients in Neova Night Therapy

Water, glyceryl stearate, stearic acid, cetyl alcohol, sodium behenoyl lactylate, octyldodecyl neopentanoate, C12-15 alkyl benzoate, cyclomethicone, dimethicone, prezatide copper acetate, sodium carboxymethyl betaglucan, camellia oleifera extract, tocopheryl acetate, sodium hyaluranate, vitis vinifera seed, squalane, prunus armeniaca kernal oil, ethylhexyl stearate, propylene glycol, isoceteth-3 acetate, propylene glycol, hydroxyethylcellulose, isopropylparaben, isobutylparaben, butylparaben, diazolidinyl urea, methylparaben, propylparaben