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* A preservative
* Please read TIA's articles on Preservatives and Are They Safe and Why Products Need Preservatives
Methylisothiazolinone, or MIT as it is sometimes known, is a preservative used in cosmetics and beauty products. It is a powerful biocide, or "chemical substance capable of killing living organisms, usually in a selective way." Biocides are a general term that includes antimicrobial, germicide, antibiotic, and antifungal. Ultimately, Methylisothiazolinone is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo. It is only approved for use in rinse-off formulas and at low concentrations.
Although many connections are made between Methylisothiazolinone and Alzheimer's disease and other conditions, research by CTFA.org and News-Medical.net shows that the concentration levels found in cosmetics and beauty products are so low that there is no risk in using products with this preservative.
Safety Measures/Side Effects:
One study at the University of Pittsburgh found Methylisothiazolinone to be a neurotoxin, but in that study, the neurotoxicity occurred after direct exposure caused a chain reaction involving zinc levels and DNA enzymes to destroy rat brain cells in culture samples. Despite this evidence, the Cosmetic, Toiletries and Fragrance Association deemed Methylisothiazolinone safe for use in cosmetic formulas (Wikipedia).
The EWG lists Methylisothiazolinone as a sensitizer and irritant. It is approved for use in rinse-off products by the CIR.
In 2016, the Canadian goverrnment revised its Hot List to include additional warnings about this ingredient. Leave on products may no longer be formulated with this ingredient. As of June 2016, children's products with this ingredient can no longer be sold in Canada. In August 2016, the European Union banned MIT from leave-on products. Companies selling in the EU have until Febraury 2017 to reformulate products to exclude MIT.