Free shipping on all domestic orders over $39

MitoQ Active Protection Daily Defense Cream - AM

Size: 1.7 oz (50 ml)

MitoQ Active Protection Daily Defense Cream works to help protect the skin from environmental aggressors like pollution while rehydrating, so your skin instantly feels comforted and looks radiant. Over time MitoQ, niacinamide, hyaluronic acid and Matrixyl® synthe’6®, a powerful anti–wrinkle peptide, work to help restructure and rebuild skin essentials so it becomes smoother, plumper and firmer. Our tester was pleased to report that this cream lessened the look of her lines and prevented new signs of aging from forming.

MitoQ is an active form of the well-known antioxidant, ubiquinone. It goes deep inside the mitochondria to power, restructure and regenerate skin cells. Matrixyl synthe‘6 stimulates six major constituents of the skin matrix and the dermal-epidermal junction, filling in wrinkles from the inside. Other actives include niacinamide, which reduces oxidative stress, anti-inflammatory chamomile CO2 and regenerating pomegranate CO2. Suitable for all skin types, this day cream is formulated to nurture and care for skin, revealing a younger-looking you.

Paraben Free Vegan, no synthetic colours, no synthetic fragrances, no DEA, TEA, no phthalates, anti-pollution actives.

TIA Review by Aida:

I am very picky about what I use on my 60-something, dry skin and am always on the lookout for face products that can both hydrate and work on wrinkles — in other words, a good multi-tasker! So, I was excited to test MitoQ Active Protection Daily Defense Cream ($135). The ingredients in this cream are said to target the skin's mitochondria and help fight against the oxidative stress that plagues our skin constantly, causing signs of aging. Over time, they work to make the skin feel smoother, firmer and more hydrated.

This cream is suitable for all skin types. For me, this usually means that the cream isn't hydrating enough. In the case of this MitoQ day cream, though, there is plenty of hydration and the plumping action helps the skin feel silky-smooth. The cream itself is midweight and sinks into the skin quickly, unlike some creams that just sit on the top of the surface. The MitoQ day cream dries down to a very natural and soft finish that lasts all day long.

The directions say to apply it by pressing the cream onto the face, throat and décolletage area. The pressing prevents micro-tears to the skin that can occur with rubbing. Although I was trying this product for four weeks, I can honestly say that I could feel a difference in my skin's hydration with the first application! IMHO there are very few products that can deliver like that — on the first try! And the hydration lasted throughout the day. I haven't tried the brand's night cream yet, but plan to do so. I think that in hot and humid weather, using the day cream at night might work well if the night cream was too heavy.

Inside you will find the brand’s proprietary complex, MitoQ, which was formulated for the cult-fave original serum. It works on the skin at the cellular level to restructure and rejuvenate. It also features the powerful wrinkle-smoothing peptide Martrixyl Synthe6. Hyaluronic acid locks in moisture to hydrate and plump up skin. Finally, there are a handful of antioxidants like niacinamide and pomegranate. There’s nothing to really dislike about this formula; it’s free of parabens, phthalate and fragrance.

I should mention that the directions also say to apply the MitoQ Serum before applying the day cream. I can only imagine that this would just pack more antioxidants into the application which would increase the overall benefit to the face. Again, the goal of the brand is to reduce the oxidative stress to the skin and reduce wrinkles. With continued use, this cream should help prevent fine lines from forming and I can confirm that I did not notice any new lines during the four-week test period. The existing ones looked lessened while using it, too.

If someone's skin feels very dry and thirsty, or if you are looking for a good day cream that doubles as an anti-ager, I would recommend giving the MitoQ Active Protection Daily Defense Cream a try. I plan to invest in the serum, day and night cream and will report back on how they work together.

Got Questions? Contact Us
read more
$ 135.00
TRU Rating
Read Review
Out of Stock
Community Review
+ Add to Compare + Add to Wishlist

Our Take

By Aida H. I am very picky about what I use on my 60-something, dry skin and am always on the lookout for face products that can both hydrate and work on wrinkles — in other words, a good multi-tasker! So, I was excited to test MitoQ Active Protection Daily Defense Cream ($135 in the shop). The... read more

Was this review helpful?

Yes / No
1 member(s) found this review helpful


1 Reviews
  • Kim B

    (4 out of 5)

    I felt comfortably hydrated all day, and maybe the thickness of it was the barrier my face needed from environmental aggressors like pollution. Though, I will say that I missed not having the convenience of a sunscreen included in the product. Most of the time I relied on the SPF provided in my foundation, which, by the way, went on just fine every time — no pilling or separating. Overall, my skin has been soft and supple while using this day cream.

    Was this review helpful to you? YES(2) | NO(0)

Write Your Own Review

You're reviewing: MitoQ Active Protection Daily Defense Cream - AM

Perfect Good OK Didn't like it Hated it Rate Me
7 + 8 =

* Required Fields

  • Marta

    May 31, 2017


    Thank you for your review Aida. I am trying the night cream and will be reporting soon (hint: it's positive).

  • Aqua (Purified Water
  • Glycerin
  • Butyrospermum Parkii (Shea) Butter
  • Simmondsia Chinensis (Jojoba) Seed Oil
  • Macadamia Ternifolia Seed Oil
  • Cetearyl Olivate
  • Cetearyl Alcohol
  • Sorbitan Olivate
  • Persea Gratissima (Avocado) Oil
  • Cetearyl Glucoside
  • Beeswax
  • Glyceryl Monostearate
  • Niacinamide (Vit B3)
  • Mitoquinol Mesylate (MitoQ®)
  • Hyaluronic Acid
  • Palmitoyl Tripeptide-38
  • Punica Granatum (Pomegranate) Seed Oil (Supercritical C02 Extract)
  • Rosa Canina (Rosehip) Seed Extract (Supercritical C02 Extract)
  • Phytosterols
  • Olea Europaea (Olive) Fruit Oil
  • Chamomilla Recutita Flower Extract (Supercritical C02 Extract)
  • Rosmarinus Officinalis (Rosemary) Leaf Extract (Supercritical C02 Extract)
  • Sclerotium Gum
  • Cetearyl Alcohol
  • Xanthan Gum
  • Sodium Gluconate
  • Benzyl Alcohol
  • Benzoic Acid
  • Caprylyl Glycol
  • Sodium Hydroxide
  • Hydroxypropyl Cyclodextrin.
Use in the morning after cleansing and applying the serum. Pump a small amount to your hand and warm in the fingertips. Press gently to your face, neck and décolletage.

Have You Tried MitoQ Active Protection Daily Defense Cream - AM?

Write your own review today
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More