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Best of 2017: Line Smoothing Serum

Is a Solution for:
Dull Skin, Fine Lines, Wrinkles
December 4, 2017 Reviewed by Marta 2 Comments

Every December we honor some of the amazing anti-aging products that have delivered unparalleled results throughout the year. The Truth In Aging Best Of Awards is now a hotly anticipated event by both our community members and our carefully-curated brands. The treatments, serums and creams we award not only meet our strict standards — innovative, ethical, good for the skin — but are also proven effective by tough critics (aka real women and men like you). So whether you are looking for a line smoother, glow booster, anti-aging eye cream or all of the above, stay tuned over the coming days as we reveal the standout products in every category.  

To kick things off, we're awarding the best serum for the treatment of fine lines and wrinkles. And the winner is...

Dr. Dennis Gross C+ Collagen Brighten and Firm Vitamin C Serum ($78 in the shop) was launched earlier this year and marks a new turning point for Dr G. This serum tackles mitochondria with an “energy complex” that includes the powerful antioxidants niacinamide, CoQ10 and superoxide dismutase.

I am on my second bottle, but when I first tested it I saw results after only two weeks. My skin was actually glowing and refreshed. Two weeks later, lines were minimized and my skin felt firm. It has become a staple in my regimen for smoothing lines and firming.

This serum was conceived as the result of Dr Gross’ tired skin theory. As Dr. Gross puts it, skin has a battery and it runs down. This battery is, in fact, mitochondria. “The powerhouse of the cell” has become the focus of a new frontier in the science of aging. As we get older, the mitochondria in our cells develop genetic mutations that cause them to either degenerate or kick the bucket. With our diminished ability to fix these mutations, the mitochondria die and thus our cells die.

Vitamin C plays a key role. It is the only antioxidant that also helps collagen production. Indeed, vitamin C is a precursor to collagen and our bodies can’t make collagen without it. One of the vitamin C derivatives used in the formula is 3-O-ethyl ascorbic acid, a stable form that has also been credited with halting the melanin-biosynthesis pathway in skin, hence it can prevent hyperpigmentation.

The collagen aspect of the formula is in the collagen amino acids and carnitine. The amino acids arginine and carnitine form something called creatine, which in turn stimulates the skin to produce more collagen and elastin. And, as mentioned in my intro, the “energy complex” also includes the powerful antioxidants niacinamide, CoQ10 and superoxide dismutase.

Dr. Dennis Gross C+ Collagen Brighten and Firm Vitamin C Serum was selected as a Five Best for Wrinkles


  • December 11, 2017

    by Marta

    Hi Eileen, that was true in the bad old days when vitamin C was unstable. Those old forms of vitamin C needed to be in high concentrations because they were quickly deteriorating and poorly absorbed. Those high concentrations made vitamin C serums drying and irritating. These days there are new forms of vitamin C that are stable, much more effective and can be used at low doses.

  • December 10, 2017

    by Eileen Escoto

    Hi, can you tell me what is the strength of the Vit c? I have read that anything under 20% is not very effective. Thanks!

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