Reviewed by Denise D.

I was so excited to be chosen to test Marta’s new favorite product, Bioeffect EGF Serum ($110). After fantastic results with the ReLuma Skin Illuminating Serum (from $135) and several other TIA-recommended products, I thought this might be the new holy grail of anti-aging. I jumped in enthusiastically and followed the instructions to a T. In the end, I think my results were mixed with some things I liked about the product and some not so much….

I started out as directed using only the Bioeffect at night and foregoing any other nighttime products. Concentrating on the right side of my face, I paid particular attention to the horizontal lines across my forehead, my “elevens” (between my brows), crow's-feet and nasolabial folds. As Marta mentioned, the serum has an oily quality to it and a little goes a very long way. There is no noticeable odor and it felt soothing going on my skin. I liked that the list of ingredients was very simple and short since my skin will flare up when I put the wrong thing on it. I also really liked the idea that the epidural growth factor, while genetically engineered to be similar to human growth factors, was grown and produced in barley plants to avoid any potential contamination issues. It seemed like a great fit to me!

Right away, I found that it cleared up a couple of dry patches that had been bothering me. After the second week, I thought I noticed that the shallowest line on my forehead was slowly disappearing and fine lines that had disappeared with the ReLuma serum were held at bay. That was enough for me - I went ahead and started using the Bioeffect on my whole forehead, but still only on the right side of the rest of my face. At the same time, I also noticed that I was starting to break out where I applied the serum between my eyebrows, so I backed off in that area.

After three weeks, I reevaluated and found that a lot of progress I made with the ReLuma was slipping away. While the shallowest forehead line continued to improve slightly, the deeper lines on my forehead were getting worse. The eye area seemed slightly improved, but I couldn’t get past the fact that my forehead was looking fatigued and saggy, as if the product was just too strong for me. I took a week and a half break over the holidays and retried the products when I returned home. Again, my forehead began to break out where I applied the serum and my skin quickly started looking tired. I should clarify that I didn’t have an irritated, flare-up reaction to this product, but more like a pimple or two in different spots because the product was just too rich. I suspect that Bioeffect is a powerful serum that works better on somewhat older skin (I’m 43) that has diminished growth factors, while my wrinkles are more the product of years of squinting at the bright California sun. All in all, I decided that the ReLuma serum worked better for me and am happy to say that after a week on that program I’m starting to see my skin looking tighter and brighter.

Ingredients: Glycerine, Aqua, Calcium Chloride, Sodium Hyalunorate, Tromethamine, Hordeum Vulgare Seed Extract, Alcohol (Ethanol) (less than 0.9%), Sodium Chloride, EGF (Transgenic Barley sh-Oligopeptide-1)