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Cellbone Hyper-Peptides Review

I have never been completely convinced by the face freezing peptides, such as Argireline, that claim to be a Botox in jar solution to anti-aging. Can a topical cream really signal muscles to move less and, thereby, inhibit the formation expression lines? Or do these potions merely give the impression of working mostly by clinging to the surface of the skin. After three weeks or so of testing Cellbone Hyper-Peptides ($76), I am a convert. My skin is tighter, has a nice glow and my forehead lines are more indistinct than they have been for the past ten years (although I am using it in tandem with other products - more on the regime a few paragraphs on).

Cellbone Hyper-Peptides has most of the ‘Botox in a jar‘ products known to man. Argireline is well known as the peptide that stops facial muscles from moving and causing expression lines. Although there are studies that show that a 10% concentration over 30 days can reduce the appearance of wrinkles by 30%, some cosmetologists seem to think that Argireline would be most effective at concentrations as high as 25%. I mention this because it is the second ingredient in Cellbone Hyper-Peptides after water. Still, Cellbone seems to be hedging its bets by including SNAP-8, created by Kinerase, is being marketed as the second generation of Argireline, and is said to be 30% more effective. Then there is Syn-ake, supposedly a mimicer of snake venom.

It is worth getting to know a bit more about these peptides. Collectively known as neuropeptides, they do not work like Botox. They don't destroy the protein, like Botox does, but keep it from connecting to the cell and turning on the muscle contraction. Paula Begoun (The Cosmetic Cop) made the comment that if they worked then the fingers you used to apply these creams wouldn't function with dire consequences for teacups or your ability to hold the steering wheel of a car. Sounds like plain old common sense, but as I've looked into it (and Erin, our own ingredients guru, has written a post on Botox in a jar ingredients), I have a different understanding of how neuropeptides work.They are small protein-like molecules used by neurons to communicate with each other. Neuropeptides can be used to target cells, communicate with them, and get them to perform specific tasks, like to repair and renew aging skin cells by stimulating the production of collagen and elastin. Our skin is naturally full of neuropeptides, but as we age, the count drops (Source). While Botox smooths wrinkles by paralyzing the muscles through an injection of a solution derived from the botulism toxin, topical ‘Botox’ alternatives attempt to phone in the request to the cells to do the work themselves. So they are not muscle relaxants that cause everything to sag at all. Back to Cellbone Hyper-Peptides. While all these neuropeptides are supposedly stopping the formation of new wrinkles and the deepening of existing ones, Matrixyl 3000 is boosting the formation of new collagen. Gotu kola (centella asiatica), idebenone and bilberry are providing the antioxidant role. Then there are several alpha hydroxy acids – cane and maple sugars and citrus fruit extracts.

I have decided to supplement Cellbone Hyper-Peptides with serums that provide additional actives such as carnosine (an extender of the number of times cells replace themselves). So every other day or so, I apply GloTherapeutics or Azure Hydropeptide over the Cellbone. In the evenings, I use YBF's Restore. I have a feeling that a new regime is emerging. I'll refine it a bit and report back on it soon.

  • June 18, 2015

    by Marta

    Hi Rose,
    Please take a look at our Five Best selection for sagging skin:

    And here are picks from our community members:

    Finally, ultrasound and LED are very helpful for firming sagging skin along the jawline, cheeks and neck:

  • June 17, 2015

    by Rose

    Hi Marta,

    I turn 60 this December. My skin has always been beautiful but I have not taken very good care of my skin until the past 10 years. However I was a wine drinker (2-4 glasses daily) until this past February. I lost 30 lbs, look good and fortunately my skin doesn't look bad for my age but I wonder if you can recommend any products that will improve sagging neck skin. I do not have a turkey neck, but the middle, right under my chin has vertical sagging and my gawls sag on either side of my chin line.

    What do you recommend?

  • February 29, 2012

    by Ilse

    Oh my just too many products and fancy things, I've used so many different products over the years. 39 yrs old, and struggle with very dark circles and I seem not to have wrinkles but when I laugh I have lots of wrinkles under my eyes so trying to keep them from becoming deep ones, otherwise my skin is good texture tends to be quite dry also

  • October 7, 2009

    by marta

    Hi Josette,
    How about checking out some ideas in our <a href="" rel="nofollow">Skin Care Regime for 40 somethings</a>:

  • October 7, 2009

    by Josette

    I am looking for a new regime. At 41 I only have lines above my lip to complain about. What would be your morning and evening reccomendations?

  • October 3, 2009

    by marta

    Janet, you can contact me at

  • October 3, 2009

    by Janet

    Thank you Marta,

    I went on there, I'm ashamed to say that I've never heard of most of these products.

    Also, I'm in search of the best products to sell in China. Do you have any recommendations? Can I have your e-mail address so we can communicate privately?

  • October 2, 2009

    by marta

    Hi Janet,
    We've put together some regimes for different age groups. Here's a link to our <a href="" rel="nofollow">30-something post</a> and here is our <a href="" rel="nofollow">50-something post</a>. And there is <a href=" -60-hippie/" rel="nofollow">Julie's</a> nearly-60-but-looks-45 regime.

    I'll come back to you on Hydroxatone and Cetaphil.

  • October 1, 2009

    by Janet

    I'm pretty confused after reading various posts & your recommended products. There are just so many products out there!! ;p

    I'm a 30 years old asian lady & is beginning to see some fine lines around my eyes. What would you recommend if I'd like to see fewer lines, prevention of freckles & boost collagen beneath my skin?

    I'm a pretty simple person & would like to stick to what works best.

    Also, will the products you recommend me work wonders on my mom & mother-in-law who are both in their 50s?

    Would you recommend hydroxatone? What about Cetaphil?


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