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Cellbone Moist Seal and the amazing gamma-PGA

Is a Solution for:
Dry Skin, Oily Skin
Reviewed by Marta March 26, 2010 2 Comments
Somehow I’d forgotten all about my bottle of Cellbone Moist Seal (it arrived when I bought the excellent Cellbone Hyper-Peptides). Actually, I hadn’t so much forgotten it as put it out of mind. Something about the name Moist Seal, followed by the words ‘hydrating gel’ conjured up the idea of something gloopy and tacky. Anyhow, I came across it in the TIA office the other day and thought I should give it a try.

First impressions reinforced my worst fears. Although not at all gloopy (rather watery, in fact), Moist Seal leaves the skin feeling sticky. In fact, I felt like a human fly paper. Fortunately, this lasts for barely one minute and then the skin feels soft, but oddly dry to the touch. While I was contemplating this, I remembered that this being a Cellbone product, it was bound to have some potent ingredients. Some of them turned out to be very intriguing – especially gamma poly glutamic acid, or gamma-PGA.

Originally found in jellyfish, gamma-PGA is these days made from fermented soy beans – a culinary gem (if you are Japanese) that is called natto. The beans are fermented with the bacterium bacillus subtilis and form foamy, gooey stuff, but its probably best not to dwell too much on that as it begins to make jellyfish seem appetizing. Talking of which, even in its industrial form as gamma-PGA, it is supposed to be edible. Anyway, the thing that makes gamma-PGA interesting for us students of cosmeticology is that it is supposed to be ten times more hydrating than sodium hyaluronate.

It may keep the skin moisturized and improve elasticity by inhibiting the activity of hyaluronidase, the enzyme that degrades hyaluronic acid in the skin. It is also said to can relieve allergic symptoms by inhibiting the permeability of inflammatory cells. However, most of the information on gamma-PGA comes from companies that manufacturer it and patent applications. I haven’t come across much research to back up the claims.

Next comes hydrogel, which is about 95% water and is used to repair tissue and, less commonly, for breast implants. But the ingredient that Cellbone makes a song and dance about is lactic calcium. Apparently this also comes from Japan and is fermented. Calcium lactate comes about when when lactic acid reacts with calcium carbonate. The reaction forms white crystals that are found in milk and other dairy products. Its pretty common in skincare products and it mainly acts as an astringent or exfoliant. What makes it special in Moist Seal – according to Cellbone – is that it comes with vitamin K2 and is, as a result, helpful in improving the skin’s elasticity. Again, I haven’t found any independent research on this.

I am curious as to how Cellbone Moist Seal ($48) will work out and I’ll report back in a few weeks.

Water, Gamma Poly Glutamic Acid, Hydrogel, Gamma Polyglutamate, Butylene Glycol, Collagen, Centella Asiatica Extract, Alovera Leaf Extract, Melon Extract, Lactic Calcium, Uva-Ursi Leaf Extract, Glycerin, Magnesium Ascorbyl Phosphate, Phenoxyethanol, Sodium Hyaluronate, Vitamin K2
  • October 5, 2011

    by JoAnna Smart

    I have to say I disagree with the results of the above mentioned comments by Oksana. My experience has been completely different.I don't know about all the ingredients and what they can do. Nor am I a make up or beauty expert. But for me, I absolutely love the products I have tried so far. I have used their peels, and they are wonderful. I am so happy with the results. I have not found a product that produces better results than this does. I am a 47 year old female that has always looked much younger than I actually am. Well, with the onset of menopause, I suddenly started aging quickly. My face suddenly started showing my age. Wrinkly, sagging facial skin. I now use the peel in conjunction with the Moist'Seal. At first, I thought maybe this was just some aloe vera, or something, because of the way it felt on my skin. Now, after using it CONSISTENTLY for about a week 2x per day, as recommended, I can see the marionette lines diminishing. My skin looks more hydrated, healthy and youthful. So, I'd recommend the product. But honestly, I don't like sharing my beauty secrets.
    I am going to continue using the products.
    JoAnna Smart

  • May 12, 2010

    by Oksana

    I have also received a bottle of Moist Seal with my Hyper-Peptides. I really, REALLY tried to like it. The description of Moist Seal on the website sounded as a perfect "opportunity" for combination skin with so many benefits on the side! Well, just as Marta, my skin first felt sticky, then dry. Although makeup went on very smooth and even, the touch-ups were a disaster. Imagine, brushing the snow off the ice - snow aside, you can see the shiny surface of the ice. Same effect with Moist Seal. Their Hyper-Peptides serum was OK, but nothing more. I am having fantastic results with SUKI bio-active 10% vit.C serum; it has peptides, copper, and lots of nourishing herbals.

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