Free shipping on all domestic orders over $39

Chella Master Protocol 7 - reviewed and recommended

Our Rating: 4 stars


Heavy hitting antioxidants and peptides to repair and protect skin


Product's claims are overstated
November 6, 2010 Reviewed by Marta 6 Comments
Definitely smooths lines and refreshes skin

Chella, a brand that is mostly sold in spas, deserves wider recognition in my view. There is usually something intelligent about their approach (for example using silk to stop sunscreen molecules from degrading and doing harm in their Anti-Aging Formula). Now there are a couple more reasons to get to know them: they have shed their old packaging for a smart and zingy silver and orange livery and their newish Master Protocol 7 serum is excellent.

Chella calls its Master Protocol 7 Cellular Defense Serum ($135) a silver bullet. That may be pushing it, but with one shot it is imparting a lot of very impressive anti-aging and wrinkle prevention ingredients. I have been using it on the left side of my face (the right side will be the subject of another post) for around six weeks and I am pleased with what I see: a definite smoothing of fine lines and refreshed, healthy looking skin.

I alluded to one of Master Protocol 7’s ingredients a few weeks ago in my post einkorn, a strain of wheat that contains a peptide with antioxidant properties that can mimic glutathione, a natural antioxidant in our bodies that fights off free radical damage.  This is a fairly new discovery my scientists and it goes into the department of cutting edge along with teprenone (Renovage).  Teprenone maintains the length of our telomeres and thereby may extend the lifecycle of our cells.

Right up top of the ingredients list is Thermus Thermophillus Ferment, a biotechnologically derived marine extract. Being heat activated (eg when the skin is exposed to the warmth of the sun), it will activate the body’s natural antioxidant enzymes. Thermophilus emzymes are very interesting to scientists and that they have a “fundamental role in DNA replication and repair.

The roll call of heavy hitters just goes on. Very much worth a call out is ergothioneine, an antioxidant amino acid that exists in our bodies and is obtained in extract form from mushrooms. Then there is trehalose. This one of those magical constituents of desert plants that helps them rehydrate after periods of draught. Trehalose is made up of sugars that form a gel as cells start to dehydrate. This stops the cells from falling apart so that they perk back into shape as soon as they are rehydrated.

Amongst the botanicals, I particularly like Limonium Narbonense – swamp sea lavender – which has the ability to protect against UVA and UVB light.

Although on the pricy side, Master Protocol 7 can’t be said to be outrageously expensive and it certainly gives value in terms of efficient ingredients. A silver bullet? Maybe not. But I’ll definitely be keeping it in my anti-aging arsenal.


Water (Aqua), Thermus Ferment, Caprylic/Capric Triglyceride, Cetyl Octanoate, Cyclopentasiloxane, Laminaria Digitata Extract, Glycerin, Cetearyl Alcohol, Cocoyl Glucoside, Cetyl Alcohol, Einkorn (Triticum Monococcum) Extract, Ergothioneine, Limonium Narbonense Flower/Leaf/Stem Extract, Tremella Fuciformis Polysaccharide, Teprenone, Adenosine Triphosphate, Sodium Chondroitin Sulfate, Olive Glycerides, Sea Whip (Pseudopterogorgia Elizabethae) Extract, Polyglyceryl-3 Stearate, Phytosteryl Isostearate, Sodium Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dimethicone, Phenyl Trimethicone, Cassia Alata Leaf Extract, Maltodextrin, Butylene Glycol, Lutein (Xanthophyll), Sodium Acrylates/Acrylonitrogens Copolymer, Pentylene Glycol, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol.

Buy Me
$ 135.00
  • November 5, 2011

    by spo

    Thanks Marta for your response... I am now trying hydrostem and so far, I love the feel when it goes on..

    I'm just using it for 2 days so it's too soon to see what it does for me, but I will report on my results.

    Again, Thanks for your help...

  • November 5, 2011

    by Marta

    Hi Spo, I find that they are all slightly different and so picking the right one for you will depend on what you are looking for. In my experience, they all have an effect on lines/wrinkles but Cell CPR is best for a moisturized dewy skin tone, Master Protocol is best at giving sagging skin a bit of a lift, and Hydrostem does the best job at wrinkles. Hope that helps.

  • November 5, 2011

    by spo

    it's almost exactly a year since this review and I'm wondering, Marta, if you ever did that 'side by side' with Skin Nutrition's Cell CPR?

    Marta, another burning question I have is how does Chella's Master Protocol 7 stack up, in your opinion, against Hydropeptide Hydrostem+6

    Thanks in advance for your response

  • December 31, 2010

    by Stephanie

    Thanks for the info Marta. Have a great trip and Happy New Year!

  • December 31, 2010

    by marta

    I really do like Master Protocol. In fact, I am away from home this week without it and find myself missing it. If money is no object, I would buy it rather than Replenish. Is it better than Cell CPR? That's a more difficult question, I find myself going back and forth between the two. I shall do a side by side test for a few weeks and see if I can form a strong opinion.

  • December 31, 2010

    by Stephanie

    Are you still using this product? Would you buy another bottle? I'd love to hear how this compares to Skin Nutrition CPR and Replenish....


Have You Tried Chella Master Protocol 7 Cellular Defense Serum?

Write your own review today
Perfect Great Good Didn't Like Hated It Rate Me
TIP: Roll over me

Join the discussion! Leave a comment Chella Master Protocol 7 Cellular Defense Serum below.

My Comment

Add a comment... Chella Master Protocol 7 Cellular Defense Serum

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More