Sephora is offering a limited edition set of the Clarisonic Brush and Kinerase C8 Intensive Treatment ($338). This is a great marketing idea before the holidays and Kinerase has got to be an improvement over the nasty cleansing lotions that Clarisonic packages with its otherwise wonderful brush, which I use almost every day to lift debris and close pores.

There's no great mystery to Kinerase products. They are all based on kinetin, a plant hormone (or cytokinin) that regulates cell growth. In Kinerase products kinetin usually appears in its synthetic version, N6-Furfuryladenine. There is one seemingly independent, 48-week clinical study, conducted in 1996 at the University of California at Irvine (until it becomes clear that it was conducted under the direction of Gerald D. Weinstein, M.D., who happens to be on the advisory board of Senetec, the company that originally made kinetin).

Kinetin isn't the only proprietary ingredient here. Acetyl octapeptide-3 is SNAP-8, a muscle contraction inhibitor that is made by Kinerase and is being marketed as the second generation of Argireline, against which it is said to be 30% more effective. According to studies (albeit published by Kinerase and not seemingly backed by any independent researchers), it can reduce the depth and appearance of wrinkles by 34.9% (Source).

A nice addition is a stable, non-irritating, but potent form of vitamin C, tetrahexyldecyl ascorbate. Otherwise there are useful, but not exceptional additions of green tea and vitamins A, B and E. As always with the Kinerase products, a lot is riding on kinetin.

Ingredients in Kinerase C8 Intensive Treatment:

Purified Water, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Caprylic/Capric Triglyceride, Stearic Acid, Kinetin, Acetyl Octapeptide-3, Camellia Sinensis Leaf (Green Tea) Extract, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Panthenol, Sodium Carboxymethyl Beta Glucan, Citrus Aurantium Dulcis (Orange) Peel Oil, Retinyl Palmitate, PEG-100 Stearate, Glyceryl Stearate, Cetyl Alcohol, Tromethamine, PPG-12/SMDI Copolymer, Carbomer, Disodum EDTA, Diazolidinyl Urea, Iodopropynyl Butylcarbamate.