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ClarityRX Get Fit Serum Review

is a Solution for:
Crow's Feet, Fine Lines, Lip Lines, Wrinkles
clarity rx get fit serum
May 9, 2016 Reviewed by Marta 12 Comments
TRU Rating
This paired down serum is a game changer!


Diminishes lines and wrinkles



In a recent Truth In Aging team meeting, we were discussing the new product pipeline and I remarked that Clarity RX Get Fit was a game changer. I don’t often use this term to describe the latest serum I am testing and everyone was more than a little surprised. As I came to write this review I had to sanity check myself, can Clarity RX really be called a game changer? Yes, it can.

Clarity RX Get Fit Multi-peptide Healthy Skin Serum ($105.75 in the shop) is very much a Truth In Aging kind of product. It has six peptides, hyaluronic acid, seaweed and a couple of preservatives. That’s it. Basically, this is all about the heavy hitters with nothing extraneous. Indeed, Clarity RX promises that its products have “no extenders, fillers, [or] bulk ingredients.” Get Fit is a worthy example.

So what makes it a game changer? Well, I am astonished by the effect on wrinkles. As I often do when I start testing, I hone in one area so that I can isolate use of the product and get a good sense of whether it works on its own. The area I chose was my crow’s feet. I have been concerned that they were getting deeper and some cross-hatching was becoming noticeable. Clarity RX Get Fit has within 30 days actually diminished them.

I started to believe that results were tangible, although subtle, after about nine or ten days and I expanded my test to include my upper lip area and from lower lip to chin. I am seeing results there as well — some of the little grooves around my lips are definitely smaller. I also started to use the serum twice a day and, lo, accelerated the results.

Get Fit is a game changer in another sense, in that it has changed my thinking on a class of peptides known as neuropeptides. I have been a little skeptical about these since they arrived in anti-aging skincare as an ingredient called Argireline. These peptides are supposed to work on our neurotransmitters to inhibit the muscle movement that cause expression lines. To be brief, I wondered whether this peptide really worked since muscles do not become immobile in the way they do after a Botox injection. And if they did, wouldn’t the unused muscles atrophy? (You can read the longer version of these thoughts in my article Will Argireline Make My Skin Sag). And anyway, products with Argireline never seemed to yield much in the way of results

More recently, this class of peptides has become populated with new versions that little-by-little have begun to convince me as they work by different mechanisms. For example, Argireline works by blocking the release of acetylcholine. Whereas Syn-ake doesn’t block acetylcholine from its release, but from its uptake by the receptors. Syn-ake is deemed to be much more effective at reducing the frequency of muscle contractions.

Given the different mechanisms, it makes sense for a formula to hedge its bets and have, in the case of Get Fit, four available: Argireline, Syn-ake, pentapeptide-18 and SNAP-8. The two other peptides in the formula are collagen-boosting ones known as Matrixyl 3000.

There is no doubt that I will keep on using Clarity RX Get Fit Multi-peptide Healthy Skin Serum. I am interested to see if the results continue. I am also curious about the rest of this brand’s line. I certainly like their philosophy, which in their own words is about being responsibly sourced, safe and healthy, plant-based, results–driven, concentrated formulas, pharmaceutical grade ingredients. Game over.

  • January 2, 2018

    by Marta

    Hi Aigerim, I think ClarityRX Get Fit would be a good choice to prevent expression lines. I can't comment on severe acne as this is considered a medical condition and you should consult a qualified dermatologist.

  • January 2, 2018

    by Aigerim

    I also have a severe acne on my jaw line, can I use vitamin A serum?

  • January 2, 2018

    by Aigerim

    Hello Marta! i am 25 years old but I have some fine lines on my nose, forehead and eye area, also crows fit.
    Can i use ClarityRX Get Fit Serum? in general, could you please advise me what products from your shop would be best for me?
    Thank you so much for your job. I am so thrilled to find your site.

  • March 29, 2017

    by cathy l mcclung

    (5 out of 5)

    I've been using Clarity Rx for 2 months in the AM only, followed by my moisturizer. I absolutely LOVE this serum, maybe my favorite facial product ever. I see the most improvement in my overall firmness. It almost seems to have smoothed out some nastiness at my jawline. My skin looks and feels a bit more taut. I stopped using it for 4 days and I could swear that I saw a difference. Once I started using it again, my jawline looked better. I might see a slight improvement in my fine lines, but that's not as evident as the seemingly improved elasticity, which is quite impressive. I will definitely continue using this serum, and plan to order before I run out!

  • June 16, 2016

    by Jessica A Alexander

    (5 out of 5)

    Marta, I want to thank you for recommending ClarityRX Get Fit Serum for my implacable forehead expression lines. I'm a HUGE fan of the Truth Vitality Lux AND of MitoQ. But, using these two products along with MANY other great TIA products have been fantastic for decreasing my "eleven", neck, crows feet, under-eye & nasolabial lines, I was STILL not making as much progress on my forehead expression lines.

    You suggested adding ClarityRX Get Fit Serum to the Truth Vitality Lux and MitoQ as the 'heavy hitters' for treating my nearly 20-year old problem. I saw improvement in my DEEP forehead lines in THREE DAYS--using it both a.m. and p.m. T'he QUANTITY of the product for the price ($105 for 1.7 ml) AND it's amazing effects make this a TIA stand-out! No discernible scent, good slip (it's a light gel), FOUR 'neuropeptides' + 2 collagen-boosting peptides--all definitely make this a product that is solving my problem VERY QUICKLY. It's ONE 'con' is the preservative phenoxyethanol.

    I've noticed that several readers question the order in which to layer great skin care products. Marta, your answers to my questions about this topic helped me too!! I wash/tone my face w/ AHA/glycolic acid products, use your Truth Vitality Lux (red LED), spray a bit of Sevani's Rose Tonique or Complexion Corrector on, and then apply the ClarityRX Get Fit Serum FIRST. I'm an ardent user of Vitamin C on my eyes, neck, & face (& B for skin/neck) in both a.m. and p.m. But, I apply my vitamins AFTER the Clarity RX. Depending on whether it's morning or evening, I add the additional products I'm going to use (usually either YBF's Defend in the a.m. or Restore in the p.m.) and finish up with MitoQ--face/forehead, neck, even my eyes (I DO use different a.m. & p.m. eye creams too--but I add MitoQ over my other eye creams).

    This product has been an ABSOLUTE GAME-CHANGER FOR ME!! I NEVER thought I'd see a decrease in my DEEP forehead expression lines. I cannot wait to see how ClarityRX Get Fit Serum performs after more than a few days!! THANK YOU Marta for bringing this fantastic product to TIA AND for personally answering my questions about which product might 'fix' my problem. Lastly, I'm appreciative of your time explaining to me how to best utilize the ClarityRX Get Fit Serum with your other 'heavy hitters' !!

  • June 15, 2016

    by Dianne Lisle-Hammond

    (4 out of 5)

    Already seeing a bit softer lines with this new serum. I will continue to use it. I just ordered another as a matter of fact! Try it!

  • May 24, 2016

    by Marta

    Hi Mary, yes you can. There's no reason why you could layer it over a vitamin C serum.

  • May 23, 2016

    by mary

    i just got the serum and wondering, if i could layer it over my marie veronique vitamin c serum?

  • May 17, 2016

    by Marta

    Hi Tracey, I have rosacea-prone, sensitive skin and had had no issues using this product.

  • May 17, 2016

    by Tracey

    Is this ok to try on rosacea type sensitive skin?

  • May 10, 2016

    by Marta

    Hi Ha, this isn't an eye serum, it is for the face. I used it on my crow's feet, which are periorbital lines. I wouldn't use it on the lids. I did not need a moisturizer on the crow's feet area, but on the lip lines I did.

  • May 10, 2016

    by hA

    Can I use this as an eye serum only? Do you recommend moisturizing after?

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