Thanks to Lori, I was recently introduced to Cosmedix Affirm. What intrigued me most was that Cosmedix Affirm was remarkably similar to Sircuit Skin’s Addict. The only substantial difference is the price: $78 for Cosmedix and $115 for Sircuit, although both can be found considerably discounted online. The formula that they more or less share looked well worth trying out and so I bought one. Guess which. Well, actually, I could have gone for a third product, Bio-Nutrient Firming Serum ($75). That one is exactly the same as Sircuit Skin’s Addict. So we have not product twins but triplets. And then I found a partial list for Bare Skin Care’s Anti-aging Serum ($24). Snap!

So what’s so good about this formula that everyone wants to put their brand name on it? One of the key actives is peumus boldus extract. This tree, native to Chile, is a well-known antioxidant and free radical scavenger. It is also called diacetyl boldine and is marketed under the name of Lumiskin as a skin brightener/lightener that inhibits the body’s melanin production.  Another scavenger is spin trap, a molecule that stops free radicals from spinning out of control and causing damage to cells (it is a favorite of the Your Best Face line).

Fullersomes is another heavy hitter. Aka fullerenes, these are more effective nutrient carriers than lipsomes and nanosomes (thanks to being up to 10 million times smaller). However, there’s been some controversy about fullerenes in cosmetics as some believe they actually cause radical damage.

There are plenty of independent studies on aminoguanidine. It seems that it inhibits the cross-linking of proteins that cause signs of aging such as break down of elastin. One researcher concluded that “aminoguanidine improves wound heating, restores growth factor TGF-β1 expression, and preserves collagen ultra structure”. Another useful ingredient is a skin hydrator, cassia angustifolia. The polysaccharides (galactomannan) from this botanical mimic hyaluronic acid.

Now, the Cosmedix Affirm that I bought has a few differences. In addition to the many shared ingredients such as the ones I have just mentioned, it has included catalase. This enzyme is super useful in that it is the catalyst that turns hydrogen peroxide into water and oxygen, which is naturally occurring but builds up over time. Catalase isn’t something I come across all that often, but it is also used in Osmosis Replenish.

All the products have green tea although Cosmedix lists its as epigallocatechin gallate, which is the major polyphenolic compound in green tea responsible for its healing and protective powers. Cosmedix has, however, struck out alone with thioredoxin, a kind of antioxidant protein that has a role in cell-to-cell communication. A less welcome initiative on Cosmedix’s part was to leave out L-carnosine, an anti-glycation agent.

I’ll be testing Cosmedix Affirm over the coming month (and, by extension, its little brothers and sisters).

In the meantime, be sure that you are not paying double for the exact same product, see our post on product twins.

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Ingredients in Cosmedix Affirm

Hamamelis Virginiana (Witch Hazel) Water, Glycine Soja (Soybean) Protein, Aqua (Water), Peumus Boldus (D-boldine) Leaf Extract, Glycerin, Catalase, Cassia Angustifolia Seed Polysaccharide, Epigallocatechin Gallate (EGCG), D-alpha-tocopherol, Silicone, Heavy Water (Deuterium Oxide), Vitis Vinifera (Grape) Seed Extract, Resveratrol, Whey Protein, Thioredoxin, Xanthan Gum, Vaccinium Angustifolium (Blueberry) Fruit Extract, Glutathione (L), Superoxide Dismutase, D-beta-glucosamine, Aminoguanidine, Spin Trap (PBN), Fullersomes, Citrus Reticulata Leaf Oil, Santalum Album (Sandalwood) Oil, Benzyl Alcohol

Ingredients in Sircuit Skin Addict:

Witch Hazel (Hamamelis Virginiana) Extract, Glycine Soja, Distilled Water, D-Boldine, (Peumus Boldus) Extract, Vegetable Glycerin, Cassia Beta-Glycan (Cassia Angustifolia) Extract, Green Tea (Camellia Sinensis) Extract, Vitamin E (D-Alpha-Tocopherol), Silicone, (Deuterium Oxide) Heavy Water/D20, Grape Seed (Vitis Vinifera) Extract, Whey Protein, Xanthan Gum, L-Glutathione, L-Super-Oxide Dismu-Tase, D-Beta Glucosamine, L-Carnosine, Resveratrol/Polydatin, L-Asca-Ridole, Spin Trap, Fullersomes, Amino-L-Ascs-Ridole, Spin Trap, Fullersomes, Amino-Guanidine, Sandalwood (Santalum Album) Essential Oil, Grapefruit (Citrus Grandis) Essential Oil.

Ingredients in Bio-Nutrient

Hamamelis Virginiana (Witch Hazel) Extract, Glycine Soja, Aqua (Distilled Water), Peumus Boldus (D-Boldine) Extract, Vegetable Glycerin, Cassia Angustifolia (Cassia Betaglycan) Extract, Camellia Sinensis (Green Tea) Extract, D-Alpha-Tocopherol (Vitamin E), Silicone, Deuterium Oxide (Heavy Water/D2O), Vitis Vinifera (Grapeseed) Extract, Whey Protein, Xanthan Gum, L-Glutathione, L-Superoxide Dismutase, D-Beta-Glucosamine, L-Carnosine, Resveratrol/Polydatin, L-Ascaridole, Phenyl Butyl Nitrone (Spin Trap), Fullersomes, Amino-Guanidine, Santalum Album (Sandalwood) Oil, Citrus Grandis (Grapefruit) Oil