Deciem NIOD Copper Amino Isolate Serum 1%

Our Rating: 4 stars

Reviewed by Marta on April 4, 2016


As members of the Truth In Aging community well know, one of my favorite ingredients is copper peptides. This ingredient is a powerful booster of collagen and restorer of hair with a long and rich research history going back to the 1970s. So Deciem’s NIOD Copper Amino Isolate Serum 1% ($60 in the shop) had me at hello.

The copper used here is a tripeptide, meaning that it has been combined with three amino acids. I was able to mentally reference the fact that in my Truth Vitality Advanced Complex for hair, the key active is copper with five amino acids. What makes NIOD’s face serum neat is that it packages the copper tripeptide-1 part of the formula separately and you mix it with what they call an activator, a copper salt from two more amino acids.

The 1% that Deciem boasts about is actually worth the hubris, as research has been conducted at 0.68% and produced results on inflammation. Talking of hubris, it is claimed that this serum will make you younger looking in only five days. I am not so sure I can concur with that, but after a month of testing it, I am convinced that it should be part of my regimen.

I didn't particularly notice wrinkle reduction as a result of my test. That may come later. But where NIOD seemed to really be helping was with firming, especially my lower cheeks and sides of my mouth going to the chin. This is where sagging tends to begin for me and I believe that the copper peptides (along with ultrasound and LED) made a difference.

NIOD Copper Amino Isolate Serum 1% really is a serum and does not for one minute pose as a moisturizer or even as a serum that can be used on its own. My slightly oily skin can often wear a serum without the need to layer a moisturizer, but not in this case. Despite the low-molecular version of sodium hyaluronate, this serum is very drying without an additional moisturizer.

One reason for this may be that it includes myristoyl nonapeptide-3, a peptide that is said to mimic retinol and exfoliate the skin in order to encourage cell turnover. There’s not much research on this ingredient that I can find. I was intrigued to see some decapeptides and an oligopeptide and discovered that along with wheat protein they are marketed as an ingredient called Renaissance Powder. The manufacturer promises it will regenerate the skin and minimize scars.

There are a couple of potential toxins amongst the preservatives and solvent that could be irritating. I had no adverse reactions. Overall, I would heartily recommend this to anyone wanting to introduce collagen-boosting copper into their skincare routine.