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DNA EGF Renewal

Is a Solution for:
Sagging Skin
June 23, 2011 Reviewed by Marta 5 Comments
I recently came across a skincare line called DNA EGF Renewal that claims to pack its anti-aging punches with an epidermal growth factor (EGF) and a repairer of DNA. Beverly Hills cosmetic surgeon, Dr Roland L Moy, is behind DNA EGF Renewal and I have to admit that I suspected it of bandwagoning. After all, plant-derived EGFs – stem cells are all the rage. Apple stem cells are what you might expect to see, but the ones here turned out to be a bit different.

The EGF in DNA EGF Renewal comes from Icelandic barley and sounds intriguing (although there isn’t much information about it anywhere) and, unfortunately as far as I can tell, it isn’t in the DNA Intensive Renewal ($125) that I have just started to try out.

Much depends, therefore, on micrococcus lysate, which is potentially behind this serum’s claims to repair DNA. It is one of those ingredients that is frustratingly hard to pin down.  It is generally accepted to be an enzyme, but I’ve it seen it described as derived from algae, milk flora, or bacteria. I am going with bacteria: micrococcus luteus. Although it can tolerate harshly hot or dry environments that barely sustain life and is supposedly UV resistant, it is much more mundanely found on the human body and one of its party tricks is to make sweat smell, well, sweaty.  To make matters worse micrococcus luteus isolated from human skin secretes an alkaline protease that degrades elastin (source).

On this basis, I was wondering what micrococcus lysate was doing here. And so was relieved to discover that the enzyme seems to be well established as a repairer of DNA and micrococcus luteus extract has been studied in after sun creams where it can reverse UV damage.

Also supposed to contain an enzyme that repairs DNA is arabidopsis thaliana, a tiny flowering plant with a very short lifespan. It has the smallest plant genome, which made it the perfect candidate for the first plant to be sequenced. It is also in ReLuma’s eye cream and the Kardashian sisters’ PerfectSkin line.

A more unusual botanical is salicornia herbacae grown in Korean salt marshes.. It looks fairly impressive as its antioxidant activity has been found to be similar to quercetin and rutin

Peptide-files will be interested to see nonapeptide-1 (Melanostatin-5), a relatively new skin lightening peptide that blocks the hormone which signals the production of melanin, thus preventing and lightening pigmentation.

The ingredient that I’m not so convinced by is musk okra (hibiscus abelmoschus). It is useful for snake bites and the seeds have a strong musk smell, which accounts for ambrette (as it is more widely known) being used by the perfume industry. I wondered if it was doing more than pong here, but this seems unlikely as the oil is mostly crude fiber (source) and in a study that compared the antioxidant activities of different plants, musk okra did not prove itself worthy of a shout out. (For future reference, the frontrunners were oak, maritime pine and cinnamon).

There is definitely enough in DNA Intensive Renewal to ignite my interest and am looking forward to seeing how the trial works out – even though there are a few things that I’d prefer to do without, such as the irritants sodium hydroxide, tetrasodium EDTA and phenoxyethanol.


Water, Glycerin, Trimethylolpropane Tricaprylate/Tricaprate, Isododecane, Isononyl Isononanoate, Micrococcus Lysate, Hibiscus Abelmoschus Seed Extract, Nonapeptide-1, Hexyldecanol, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Batyl Alcohol, Stearic Acid, Arabidopsis Thaliana Extract, Salicornia Herbacae Extract, Nymphaea Alba Flower Extract, Tocopheryl Acetate, Brassica Campestris (Rapeseed) Sterols, Cetylhydroxyproline Palmitamide, Sodium Palmitoyl Proline, Bisabolol, Butylene Glycol, Xanthan Gum, Tetrasodium EDTA, Allantoin, Lecithin, Sodium Hydroxide, Soybean Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dimethicone, Caprylic/Capric Triglyceride, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol
  • May 25, 2017

    by Kay

    I was very excited for this, but honestly I don't think it did anything. It was hydrating, at best, but a complete waste of a hundred-some dollars.

  • September 30, 2011

    by Howard

    I honestly wondered about this if other pruducts uwithin thihis line something about .9 I am wondering if this is already in you your skin ...what benefit would this have

  • June 30, 2011

    by Sheree

    Thanks Marta!
    I've looked at the LED light systems, I just really wondered if they worked. Heck, I've bought everything else under the sun, guess that will be my next purchase!
    Thanks so much for your reply, it's truly appreciated.

  • June 30, 2011

    by Marta

    Hi Sheree
    I know what you mean about bending forward. Although good face creams can help in making skin a little firmer, the things that made a difference for me were microcurrent and LED treatments. I haven't found a good way to do microcurrent at home (it requires some expertise and the right kind of machine). I have it done at a salon once a month. My at home use of LED light really does make a difference. I would really urge you to start there. The Sirius Aurora is affordable and regular use plumps and firms. You can read more about my salon treatments here: And for more on LED at home:

  • June 29, 2011

    by Sheree

    I was just about to post on your facebook page...I am so trying to find something that helps with sagging skin. Seems like every one writes about wrinkles and all of the anti aging creams and serums seem to be targeting wrinkles, which I have very few of. But I swear...when I bend over it feels like my skin is falling off my face!! Anyway, right now I'm about done with my first jar of Juice Beauty's stem cellular repair moisturizer. I have another so I can continue usage. I'm going to give it two months to see if it helps any with sagging...:/

    I'll look forward to your review of the DNA EGF Renewal!

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