Free shipping on all domestic orders over $39

Dr. Dennis Gross Skincare C+ Collagen Brighten and Firm Vitamin C Serum Review

is a Solution for:
Age Spots, Dry Skin, Dull Skin, Fine Lines, Hyperpigmentation, Sagging Skin, Uneven Skin, Wrinkles
Dr. Dennis Gross Skincare C+ Collagen Brighten and Firm Vitamin C Serum
March 20, 2017 Reviewed by Marta 2 Comments
TRU Rating
This advanced vitamin C serum energizes skin cells and fuels collagen production for a more youthful-looking complexion


Increases glow, lessens the look of lines and tightens skin


Contains some undesirable ingredients

Dr. Dennis Gross, a dermatologist in New York City, believes he has come up with a new approach to anti-aging skin care by treating what he calls “tired skin.”  There’s much more to this theory than being washed out after a bad night (or a really good night, for that matter), and he is introducing a new line of products with the brand’s proprietary vitamin C technology and a collagen-boosting complex. Is he really on to something new? To find out, I tested the C+ Collagen Brighten and Firm Vitamin C Serum ($78 in the store).

This review is being written after 30 days of testing, but I have to say that after only two weeks I was noting a very different look to my skin. It was the opposite of tired. It was actually glowing. I couldn’t believe how refreshed my skin looked. Two weeks later, lines were minimized and my skin felt firm. I’m actually putting that to the test as I write this by tapping and pinching my lower cheek. Tight as a drum. Dr. G has come up with something that really does move the needle, which leads me to the inevitable pun that with this serum, you can put off the needle.

So, before I run through the ingredients with you, a quick reprise of the tired skin theory. As Dr. Gross puts it, skin has a battery and it runs down. This battery is, in fact, mitochondria. “The powerhouse of the cell” has become the focus of a new frontier in the science of aging. As we get older, the mitochondria in our cells develop genetic mutations that cause them to either degenerate or kick the bucket. With our diminished ability to fix these mutations, the mitochondria die and thus our cells die.

C+ Collagen is the solution, according to Dr. Gross. Vitamin C has long been one of the good doctor’s favorite ingredients, as it is the only antioxidant that also helps collagen production. Indeed, vitamin C is a precursor to collagen and our bodies can’t make collagen without it. One of the vitamin C derivatives used in the formula is 3-O-ethyl ascorbic acid, a stable form that has also been credited with halting the melanin-biosynthesis pathway in skin, hence it can prevent hyperpigmentation.

The collagen aspect of the formula is in the collagen amino acids and carnitine. The amino acids arginine and carnitine form something called creatine, which in turn stimulates the skin to produce more collagen and elastin. The “energy complex” also includes the powerful antioxidants niacinamide, CoQ10 and superoxide dismutase.

Also worth a shout out is turmeric, an antioxidant and skin brightener. There’s also a flavonoid called quercetin, which is abundant in onion leaves and papaya shoots, as well as in guava. The thing about quercetin is that it may be a much more of a powerful antioxidant than was previously thought. Cornell University has a new way of measuring antioxidant potency called cellular antioxidant activity (CAA) that tests the antioxidant activities of a compound inside the cell itself. This is an approach that is deemed to be more accurate. Of all the flavonoids, quercetin had the highest CAA value.

There are the usual suspects in the form of harsh preservatives and denatonium benzoate, a bitter substance used in denatured alcohol. Nonetheless, my skin tolerated this serum perfectly well. Overall, I do think that Dr. Gross has come up with a breakthrough product that I will be keeping as part of my beauty arsenal. I intend to use the bottle until done (another couple of months, I should think) and will be interested to see if I keep my new-found glow while continuing to pass the tap and pinch tests. So far, C+ Collagen Brighten and Firm Vitamin C Serum is highly recommended.

  • December 7, 2017

    by Cindy

    I am actually VERY surprised that this serum won the award for best line smoothing serum. With the amount of denatured alcohol (as read in a previous article referring to bad forms of alcohol) in this product I am left perplexed.......

  • March 20, 2017

    by Melissa

    I recently started using Dr. Dennis Gross's product line. My first venture so far is his Ferulic + Retinol triple correction eye serum. After just a week, I am already seeing a difference in that my eyes don't look as tired. I would love to try his new C+ collagen brighten and firm serum to see if it can help even out the skin on the rest of my face so that it will look as great as my eyes!

Have You Tried Dr. Dennis Gross C+ Collagen Brighten and Firm Vitamin C Serum ?

Write your own review today
Perfect Great Good Didn't Like Hated It Rate Me
TIP: Roll over me

Join the discussion! Leave a comment Dr. Dennis Gross C+ Collagen Brighten and Firm Vitamin C Serum below.

My Comment

Add a comment... Dr. Dennis Gross C+ Collagen Brighten and Firm Vitamin C Serum

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More