Free shipping on all domestic orders over $39

Dr Sebagh's anti-aging skincare

February 25, 2012 Reviewed by Marta 6 Comments

Dr Sebagh is Cindy Crawford’s Paris-based derm and the expert inspiration behind her mediocre Meaningful Beauty line (which has been reviewed by Truth In Aging readers, such as Lynne without much enthusiasm (although Diane had a more generous verdict). The good doctor’s personal and much more upscale range, the eponymous "Dr Sebagh" has just launched in Barney’s and so I was curious to see if his formulas would improve when left to his own devices.

If anything, they are worse. Especially considering the steep prices. First, I took a look at Dr Sebagh Serum Repair $140.  The first thing that I was struck by was the claim that it “contains 50% hyaluronic acid”. Oh, is that a fact? Actually, I don’t think so.

I once did some digging into products that claim high percentages of hyaluronic acid (sodium hyaluronate) and even half that amount would be a physical impossibility. Most skincare formularies recommend HA be used at a rate of .01% to 1%. Anything more results in a useless, thick goo. Imagine making Jell-O but only using 1/10th the water and you will get the idea. I had lot of fun making a video to demonstrate this.

More plausibly Serum Repair also has hydrolyzed collagen, glycerin and the peptide known as Matrixyl. However, Dr Sebagh seems to be a bit of a micro-phobe as about half the ingredients – seven to be exact – are preservatives including most parabens known to man, the possible neurotoxin, phenoxyethanol, and two irritants.

Priced audaciously at $350, Dr Sebagh’s newest product is Supreme Night Secret, which is supposed to use “the latest biotech cosmetic ingredients to work with the skin’s natural body clock”.  Most of the first 20-odd ingredients are worthless and the rest are not much to write home about. The exception might be an alga and it is this that seems to be the “biotech” ingredient that works with the body clock. I found a patent application that makes all sorts of claims about its ability to repair cellular structures. The amusing part is that this particular algae euglena gracilis lives and multiplies in the absence of light – hence, its use in night cream I would guess. So if you do fork out $350 for Supreme Night Secret, don’t sleep with the light on as you may render this active ineffective.

In order to buy Supreme Night Secret, you’d have to believe in it as there isn’t much else here apart from perfectly good, but not game-changing, ingredients such as shea butter, wheat germ, rosehip and tribehenin. As far as being an active, I’m not sure I understand what this alga does in skincare. Another cosmetic brand, Cellbone, says it “triggers cell metabolism by stimulating calcium release”. But I haven’t found anything to back this up, despite the myriad studies on this it. One of those studies said that euglena gracilis can synthesize tryptophan, an amino acid that is a natural sedative (its in turkey and explains the Thanksgiving nap). So perhaps Supreme Night Secret at the very least will send you off for a good night’s sleep.

See our FIVE BEST recommendations including Five Best for sagging skin, Five Best with vitamin C and Five Best eye creams

Ingredients in Serum Repair: Aqua (Water) - Hydrolyzed Collagen - Sodium Hyaluronate - Glycerin - Butylene Glycol - Carbomer - Polysorbate 20 - Palmitoyl Pentapeptide-3 - Phenoxyethanol - Methylparaben - Butylparaben - Ethylparaben - Propylparaben- Methylchloroisothiazolinone – Methylisothiazolinone

Ingredients in Supreme Night Secret: Aqua (Water), Cyclopentasiloxane, Glycerin, Dicaprylyl Ether, Peg-12, Euglena Gracilis Extract, Caprylic/Capric Triglyceride, Biosaccharide Gum-4, Cetyl Alcohol, Glyceryl Stearate, Butyrospermum Parkii Butter, Cetearyl Alcohol, Dimethicone, Polymethyl Methacrylate, Silanediol Salicylate, Hexyldecanol, Hydrogenated Palm Kernel Glycerides, Caprylic/Capric/Succinic Triglyceride, Phenoxyethanol, Glyceryl Dibehenate, Magnesium Aluminum Silicate, Rosa Canina Fruit Oil, Polyacrylate-13, Peg-75 Stearate, Aroma (Flavor), Tribehenin, Alpha-Glucan Oligosaccharide, Propanediol, Ceteth-20, Steareth-20, Polyisobutene, Chlorphenesin, Caprylyl Glycol, Sesamum Indicum Oil, Glyceryl Behenate, Safflower Oil / Palm Oil Aminopropanediol Esters, Hydrogenated Palm Glyceride, Bht, Wheat Germ Glycerides, Algin, Geranylgeranylisopropanol, Phoenix Dactylifera (Date) Seed Extract, Polysorbate 20, Tocopheryl Acetate, Rhizobian Gum, Sodium Hyaluronate, Potassium Sorbate, Sodium Methylparaben, Tocopherol, Methylparaben, Propylparaben, Butylparaben, Ethylparaben, Ci 14700 (Red4), Isobutylparaben, Magnesium Nitrate, Citronellol, Benzyl Alcohol, Geraniol.


  • March 16, 2018

    by Muth'ra

    These products are obviously overpriced scams but I have to correct your article. I don't know if you were joking or merely ignorant but you made two silly comments about Euglena gracilis:

    "The amusing part is that this particular algae euglena gracilis lives and multiplies in the absence of light – hence, its use in night cream I would guess. ... don’t sleep with the light on as you may render this active ineffective."


    "One of those studies said that euglena gracilis can synthesize tryptophan, an amino acid that is a natural sedative the very least will send you off for a good night’s sleep."

    Those comments are ridiculous because the ingredient is Euglena Gracilis EXTRACT, not living organism. No living organism can survive in all those chemicals, which include preservatives. Extracts do not "synthesize trytophan," reproduce or react to light. In other words, your conclusions are invalid. That doesn't prove that the creams work, but you certainly haven't disprove it either.

    Muth'ra Gupta, PhD

  • October 22, 2016

    by Mary lou

    Thanks !I was about to spend 1000.00, but when I read the reviews I decidedto spend my money on a more reliable lesser expensive creams.

  • December 10, 2015

    by Michele

    I also bought thee products from a savvy slaeswomen at Heathrow airport in November 2015..and after $1500 spend..... no improvement in my skin...and in fact my skin feels drier now than before..
    If you see Dr Sebaghs videos online...he is all about Botox...
    Complete con!!

  • October 16, 2013

    by Sus

    I bought the super-expensive "Dr Sebagh Supreme Neck Lift (50ml) Neck & Décolleté Cream" at Heathrow from a very good sales-woman, and I have now tried it for 6 weeks, morning and evening, without ANY improvement of the skin of my decollete area..!

    I am very disappointed, as I expected that this very over-priced cream would definitely keep its promise at such a high price, I thought I would at least see a slight improvement ,but NONE WHATSOEVER.
    Buy a cheaper cream, maybe a heavier moisturizer, or even a good anti-wrinkle serum from the pharmacy would be cheaper than this one and still work better. I've tried antiage serums before to my face where I saw a definite improvement of my skin, so I know there are better products out there than this one.


    (Dr Sebagh Supreme Neck Lift (50ml) Neck & Décolleté Cream)

  • February 25, 2012

    by Barbara

    For antiaging and in conduction with face creams, I bought the book,"oxygen Yoga : A Spa Universe" and learned a lot about the power of oxygen and antiaging. My mind feels better, my body is great and my appearance has never looked better. You still need. Great face creams, but the combination is great.

  • February 25, 2012

    by Dennis

    Disgraceful product, disgraceful pricing

Join the discussion! Leave a comment below.

My Comment

Add a comment...

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More