Free shipping on all orders over $39

Five Best over the counter anti-wrinkle retinol creams

Solution for:

Fine Lines, Wrinkles
Reviewed by Marta March 9, 2013 15 Comments

This post has been updated. See Five Best with Retinol 2014.

Retinol, it must be said, is very good at reducing fine lines and giving the complexion a boost. So good, in fact, that it is easy to get addicted. Beware, retinol is a heavy-duty exfoliator and overuse may irritate the skin and even thin it.

What Is Retinol? Why Do Anti-Wrinkle Retinol Creams Work?

Retinoids are highly active and produce relatively quick skin changes but the speed and intensity of the changes is dependent on the form and dose, as well as an individual’s tolerance. Our Five Best over-the-counter anti-wrinkle retinol buys have been tested by me and members of the Truth In Aging community and have been selected because, along with retinol, they are packed with other great anti-aging ingredients.

  • Omosis Correct

    Omosis Correct ($56). An excellent and effective product that fades wrinkles and smooths the skin whilst being relatively gentle. The secret is that niacinamide backs up the action of trans retinal. Plus there are anti-aging heavy hitters such as copper peptides and epidermal growth factor that repair wrinkles, as well as R-Lipoic acid. A great anti-wrinkle retinol product at any price and very good value at less than 50 bucks.

  • PSF Retinol Nite Repair

    PSF Retinol Nite Repair ($46). A good product at a good price. It packs its punch with a 1% concentration of pharmaceutical grade retinol. Alpha lipoic acid is an interesting additional ingredient that is supposed to prevent vitamin C and E deficiency. Counteracting the irritant effects of retinol are aloe, neem oil and willow bark, which has salicin (similar to aspirin) in it. Unfortunately, I am less keen on the butylated hydroxytoluene (BHT), a preservative that has been banned as a food additive in Japan and Europe.

  • Skinfinite Platinum PM Cream 1% Retinol

    Skinfinite Platinum PM Cream 1% Retinol ($79 in the shop). Truth In Aging reviewer, Mark, said: I didn’t experience any redness, irritation or flaking (as I did initially with retin-A, even with cautious use) and I do attribute that to gradual use, and most likely the improvement in the delivery system of the product.  It left my skin smooth and even toned. Interestingly, instead of drying my skin out, it actually hydrated it thanks to several moisturizing ingredients such as shea butter, almond oil, beta-glucan(D), and ceramide-2”. Skinfinite says its retinol is entrapped in molecular microsponges that enhances skin penetration in a time-release delivery system. Another reviewer, found this anti-wrinkle retinol cream too strong to use more than once a week.

  • Arcona Vitamin A Complex Repair

    Arcona Vitamin A Complex Repair ($68). Arcona put two retinoids in their Complex Repair (PM). Retinol, the alcohol form of vitamin A, is the third ingredient, and retinyl palmitate is further down at 10th position. For anyone who likes retinoids, this is a great one to try because the overall formulation is so clean, lightweight and you won’t have to wait too long to see some changes. Truth In Aging reviewer, Jaysie, said she “was quickly aware of a tightening effect, but also a smoothing effect. For anyone who likes retinoids, this is a great one to try because the overall formulation is so clean, lightweight and you won’t have to wait too long to see some changes."

  • Prana Reverse A

    Prana Reverse A ($48 in the shop). An excellent retinol that does a great job of bringing down sun damaged skin. If you have stubborn areas of aging skin or hyperpigmentation and want a relatively effective over the counter anti-wrinkle retinol cream, then Prana Reverse A is worth trying out. Reverse A gets my vote for its natural ingredients and slew of anti-agers. Alpha lipoic acid is an antioxidant and produces energy in cells and I especially like l-Carnosine, which flushes toxins from the body and may extend the Hayflick Limit (the number of times cells reproduce themselves). NaPCA crops up in a few of Prana’s products and sounds a little like hyaluronic acid (which is also here) in that it Na-PCA it pulls water out of the air to moisturize the skin.  With botanical sage, horsetail and chamomile, Reverse A also has calming effects and may help with broken capillaries. The vitamin A is rounded out with Vitamin B5, E and C.

  • July 18, 2014

    by dee

    I have been reading about Revitol over on and it sounds good. Has anyone had any experience with this product? Apparantly, it is better than Botox. Sounds too good to be true. That's why I am looking for some "human" experience of this product.

    I get so fed up with fake reviews/

  • May 22, 2011

    by Kim Y.

    Dr. Oz says to use help me cream by philosophy, $45 for 1.05 oz at amazon. Looks to have some great reviews, so I took a chance and bought a kit from (also came w/free gift and I looked up promo codes to get 15% off + free shipping! Waiting to get it so we'll see!

  • May 28, 2009

    by Evelyn Andreoli

    I have just found this cream on the Internet and I am interested in it. I have not heard of it before and was checking up on Dermapril-SP, Prevage and Dermitage Products. I had a CO2 Lazer Treatment done and I am looking for a product that will suit my skin. I have used Dermitage for a short time before the treatment and it was nice. I have also used Stridi Vectrin for about 3 years. I am now using the bleaching cream and MD Mositerizer until the Dr. Chang says I can start using something else.

    Some say that the product Prevage with Idebenone is the best and others say that Dermapril-SP with Matrixyl 3000 and Argatensyl is the best. Now MyChelle Supreme says no to Matrixy; 3000.

    The regiment that is said is best is:

    Anti=Aging Products (antioxidant, Retinoid, MMP Inhibitor)
    Sunscreen Daily (UVA &UVB)

    So now what do I buy is the trick.??

  • April 10, 2009

    by Christine

    Hi, Marta,

    Have you tried Pantaxyl yet?

  • March 26, 2009

    by marta

    Victorial Principal's line uses Argireline. This peptide is supposed to reduce facial muscle movement and the production of expression lines. Nothing wrong with it, but its not outstanding. The rest of the ingredients aren't listed.

    Sorry, but I'm not qualified to make recommendations linked to surgical recovery. That's between you and your surgeon

Join the discussion! Leave a comment below.

My Comment

Add a comment...

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More