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Five Best products with Matrixyl 3000- 2010

March 29, 2010 Reviewed by Marta 5 Comments

It was my review of KaplanMD Perfecting Serum that made me realize that it has been a year since we last did a round up of products with Matrixyl 3000. This combination of two peptides (palmitoyl oligopeptide and palmitoyl tetrapepide-3 – sometimes called tetrapeptide-5) specifically stimulates collagen synthesis and skin repair (here’s more than you ever wanted to know on Matrixyl 3000). Frustratingly, there is still no independent research on its results. But although Matrixyl 3000 shares potion space with many other potent antiagers these days, it still remains a formulator’s favorite and is one of the most searched terms on Truth In Aging.

In fact, Your Best Face Correct ($150 in the TIA shop) is a case in point – it has recently been reformulated but Matrixyl 3000 survives. Another eye cream, but better suited to those on a budget is Dermaradiant Ageless Eyes ($29). A new favorite is Cellbone Hyper Peptides and a perennial cosmetic friend is Calvin Klein’s antiaging foundation.

Your Best Face Correct ($150). This is still my hands down favorite eye cream and I am pleased to be converting my friends one by one. I was glad to hear from one of them that Correct eliminated her dark under eye circles for the first time in her life. In addition, it is a great firmer and smoother. Say goodbye to crepe. The formula has recently been updated and, as well as Matrixyl 3000, it now includes some of the latest heavy hitters known to cosmeceuticals such as teprenone, lipochroman-6 and Syn-Tacks.

KaplanMD Perfecting Serum. It took me a few weeks to realize that my skin was really liking this serum. I find it extremely hydrating and my skin feels comfortable and it has a great glow. This has a whopping 50% sodium hyaluronate. The ten actives include Dr Kaplan’s signature black cohosh, which along with grape and soy, is supposed to counteract to depletion of estrogen that women experience as they age and is one of the three causes of skin aging identified by Dr K. As well as Matrixyl 3000, one of my favorites here is carnosine, which can also be found in many products by Osmotics. Carnosine is a natural amino-acid that is a potent anti-oxidant, it helps to chelate ionic metals (flush toxins from the body), it has immune boosting properties. The thing I find exciting is that Australian researchers claim it can extend the HayFlick Limit.

Cellbone Hyper-Peptides ($76). With this my skin became tighter and forehead lines more indistinct. Along with Matrixyl 3000 there are the neuropeptides, Argireline and SNAP-8. Gotu kola (centella asiatica), idebenone and bilberry are providing the antioxidant role. Then there are several alpha hydroxy acids – cane and maple sugars and citrus fruit extracts.

DermaRadiant Ageless Eyes ($38) is well-priced eye cream given the quality of the ingredients. In addition to the Matrixyl 3000, there hesperidin methyl chalcone, which promises to send your bags packing. There is also biotin, which is vitamin B7. I like the inclusion of montmorillonite, a mineral clay whose forte is to detoxify resulting in a clearer complexion. Amongst the botanicals, there is centella asiatica. This is also called gotu kola and it is a wound healer as well as an anti-inflammatory. Europhrasia officianalis is also known as eyebright – need I say more. Rosa canina is a good source of vitamin C.

Calvin Klein Infinite Matt Oil-free Foundation ($32). Its good to find a foundation that gives more than a nod to antiaging. This one has matrixyl 3000 and green tea. There is also gotu kola (centella asiatica), a plant grown throughout Asia that, because of its skin healing properties, was traditionally used to treat leprosy. Its abilities as a wound healer and rebuilder of type 1 collagen are documented in Aesthetic Plastic Surgery.

See all our 2013 FIVE BEST recommendations including Five Best for sagging skin, Five Best with vitamin C and Five Best eye creams

  • June 11, 2013

    by Marta

    Hi SusanG, Cell-CPR does not have M3000. But plenty of other peptides: Hexanoyl dipeptide-3 (which is lecithin and norleucine Acetate) activates skin cell regeneration by stimulating the natural desquamation process of the skin, leading to a gentle peeling. Rh-oligopeptide-1 (Egf) is a recombitant human epidermal growth factor. And copper tripeptide (also known as copper GHK).

    One of the most fascinating ingredients is adenosine triphosphate (ATP), an ingredient that is also in DermaSilk. It is the main energy source for the majority of cellular – and muscular – functions. This includes the synthesis of DNA. The full review is here.

    How are you getting on with it? Let us know

  • June 11, 2013

    by SusanG

    Marta, does Skin Nutrition Cell-CPR have the Matrixyl 3000 in it? If not, isn’t there some other powerful peptide(s) in it? (I recently purchased the Cell-CPR upon seeing it recommended by TIA). Thanks much, Susan

  • October 2, 2010

    by Lauretta

    Hi, Are you familiar with the BabyFace brand? It's out of Newport Beach, CA and the prices are unbelievably cheap. Lots of items with peptides, etc. I just wonder if it's too good to be true.

  • June 25, 2010

    by Alice Serna

    I recently started using a products from Diamond Lifestyle corporation's Multi-Active Concentrate that contains 5% of Matrixyl 3000 and the firming eye serum which contains 3% of Matrixyl and 5% of Eyeliss. These products are awesome. Immediate lessening of wrinkles and eyebags are seen after application!!!! Very affordable too.


  • June 6, 2010

    by Kerence

    I have been using DermaRadiant Ageless Eyes and love it so much! The service that the company provides is really impressive too; they sent my DermaRadiant Ageless Eyes down to Oz with speed and also sent a full size face cream as an unmentioned bonus. Needless to say I was very happy!
    Before I was using Cosmedix eye believe liquid crystal serum at more than 4 times the price and less impressive results.
    DermaRadiant Ageless Eyes is a light cream that instantly makes your eyes look better. I really enjoy putting it on!

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