It was my review of KaplanMD Perfecting Serum that made me realize that it has been a year since we last did a round up of products with Matrixyl 3000. This combination of two peptides (palmitoyl oligopeptide and palmitoyl tetrapepide-3 – sometimes called tetrapeptide-5) specifically stimulates collagen synthesis and skin repair (here’s more than you ever wanted to know on Matrixyl 3000). Frustratingly, there is still no independent research on its results. But although Matrixyl 3000 shares potion space with many other potent antiagers these days, it still remains a formulator’s favorite and is one of the most searched terms on Truth In Aging.

In fact, Your Best Face Correct ($150 in the TIA shop) is a case in point – it has recently been reformulated but Matrixyl 3000 survives. Another eye cream, but better suited to those on a budget is Dermaradiant Ageless Eyes ($29). A new favorite is Cellbone Hyper Peptides and a perennial cosmetic friend is Calvin Klein’s antiaging foundation.

Your Best Face Correct ($150). This is still my hands down favorite eye cream and I am pleased to be converting my friends one by one. I was glad to hear from one of them that Correct eliminated her dark under eye circles for the first time in her life. In addition, it is a great firmer and smoother. Say goodbye to crepe. The formula has recently been updated and, as well as Matrixyl 3000, it now includes some of the latest heavy hitters known to cosmeceuticals such as teprenone, lipochroman-6 and Syn-Tacks.

KaplanMD Perfecting Serum. It took me a few weeks to realize that my skin was really liking this serum. I find it extremely hydrating and my skin feels comfortable and it has a great glow. This has a whopping 50% sodium hyaluronate. The ten actives include Dr Kaplan’s signature black cohosh, which along with grape and soy, is supposed to counteract to depletion of estrogen that women experience as they age and is one of the three causes of skin aging identified by Dr K. As well as Matrixyl 3000, one of my favorites here is carnosine, which can also be found in many products by Osmotics. Carnosine is a natural amino-acid that is a potent anti-oxidant, it helps to chelate ionic metals (flush toxins from the body), it has immune boosting properties. The thing I find exciting is that Australian researchers claim it can extend the HayFlick Limit.

Cellbone Hyper-Peptides ($76). With this my skin became tighter and forehead lines more indistinct. Along with Matrixyl 3000 there are the neuropeptides, Argireline and SNAP-8. Gotu kola (centella asiatica), idebenone and bilberry are providing the antioxidant role. Then there are several alpha hydroxy acids – cane and maple sugars and citrus fruit extracts.

DermaRadiant Ageless Eyes ($38) is well-priced eye cream given the quality of the ingredients. In addition to the Matrixyl 3000, there hesperidin methyl chalcone, which promises to send your bags packing. There is also biotin, which is vitamin B7. I like the inclusion of montmorillonite, a mineral clay whose forte is to detoxify resulting in a clearer complexion. Amongst the botanicals, there is centella asiatica. This is also called gotu kola and it is a wound healer as well as an anti-inflammatory. Europhrasia officianalis is also known as eyebright – need I say more. Rosa canina is a good source of vitamin C.

Calvin Klein Infinite Matt Oil-free Foundation ($32). Its good to find a foundation that gives more than a nod to antiaging. This one has matrixyl 3000 and green tea. There is also gotu kola (centella asiatica), a plant grown throughout Asia that, because of its skin healing properties, was traditionally used to treat leprosy. Its abilities as a wound healer and rebuilder of type 1 collagen are documented in Aesthetic Plastic Surgery.

See all our 2013 FIVE BEST recommendations including Five Best for sagging skin, Five Best with vitamin C and Five Best eye creams