Truth In Aging's Five Best are updated whenever we come across new, high performing products. As always, the criteria are: we've seen the evidence with our own eyes; the ingredients come with compelling evidence that they work; they do as little evil as possible.

Powerful new products can topple previous Five Bests and two have been ousted from February's Five Best Serums: Boots No 7 Restore & Renew (I developed an allergy to it, as did a couple of other people who wrote in to Truth In Aging) and Zelens Radical Defense Serum (it did nothing for me, the new formulation no longer contains the powerful fullerenes anti-oxidant and it has Arguirline, which I regard as pointless).  You can see the full February Five Best Serums by clicking here.

Osmotics Anti-Radical Age Defense. This is a veritable new and notable. I am using this where I need a more intense wrinkle repair and I am already noticing results. The long term effects could be very good if the two most interesting active ingredients live up to expectations. They are carnosine, which is supposed to extend the Hayflick Limit, and aldenine, which boosts production of collagen III. It also has CoQ10 and dimethylmethoxy chromanol, another anti-oxidant with a good pedigree. You can find out more about these ingredients by following the links at the end of this post.

Image Skincare's Ageless Total Anti-Aging Serum. I am on my second bottle. Supple and healthy skin seems to be the result and its doing wonders for my neck. It contains two key things: acids (glycolic and lactic) and the matrixyl peptide that is a very good anti-oxidant. Plus there's lots of plant extracts and soothing arnica. Because of the acids, I give myself a couple of days off each week.

Tracie Martyn Firming Serum. On my Image Skincare days off, I switch to Tracie Martyn or Remergent (see below). This has been a staple for many years now. It is nourishing and soothing, as well as being full of anti-oxidants.

Mychelle Supreme Polypeptide Cream. This one of the better matrixyl 3000 (a potent anti-oxidant) creams out there. Not only is it packed full of good things and does no evil, several people have told me they are getting great results from it.

Remergent DNA Repair Formula Age Retaliator Serum. This made it to Five Best for the first time in February.The key ingredient is an enzyme extracted from plankton that
is supposed to repair DNA. Otherwise the ingredients are pretty similar to Image Skincare
- plant extracts and AHAs, but with a different anti-oxidant, ergothioneine. I am still in two minds about it and am not sure it is doing much for me. It may also be responsible for the odd breakout. I'll give it more time, but I fear it might not make it to the next update.