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Five Best with Ceramides

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August 7, 2013 Reviewed by Marta 5 Comments

This post has been updated: Five Best with Ceramides 2014

Ceramides are the glue that holds our skin surface cells together. There are different ceramide types (conveniently numbered – i.e., ceramide-3) and six are commonly found in skin. All four layers of the epidermis contain ceramides, and they play an important role by creating a barrier that reduces infection and helps to retain the skin’s moisture. Reduction in the amount of ceramides may result in dry skin, dermatitis, or wrinkles.

Phytoceramides are the plant-derived equivalent of ceramides, a lipid that keeps your skin hydrated and plump. Supplements with phytocermides are mostly obtained from wheat. In oral supplement form, they got some attention from Dr. Oz, although there’s no research to back them up. Ceramide in topical skincare, on the other hand, does have a good scientific pedigree and has been shown to improve moisture, skin barrier repair and resistance to aging. (Read more on phytoceramides and ceramide). Here are my Five Best with ceramides.

  • Osmotics Anti-Radical Age Defense

    Osmotics Anti-Radical Age Defense ($111). This classic from Osmotics stands the test of time. It is great for wrinkles, broken veins and skin tone. As well as ceramide (a favorite Osmotics ingredient), this anti-aging treatment attacks free radicals that damage skin cells in three different ways, with carnosine and aldenine. Aldenine is also an exciting ingredient. A combination of soy, wheat and tripeptide 1, it boosts the production of collagen III (type we had when we were children), and protects the cells from photodamage. It’s supposedly able to boost collagen production by 300% in just seven days. Anti-Radical Age Defense is a wrinkle repairer and mender of broken veins.

  • Skinfinite Platimum 1% Retinol

    Skinfinite Platimum 1% Retinol ($63 in the shop). Yes, this has ceramide, but it also has a 1% retinol. It is one of the few retinol creams that get my vote. It doesn’t seem to irritate and there are good results within two months. Skinfinite chose ceramide 2, which enhances the expression of a special enzyme that is anti-inflammatory. Another active here is beta glucan, known to enhance the immune system. Skin is hydrated with shea butter and sodium hyaluronate, so unlike many retinols, Skinfinite Platinum is not drying.

  • Snowberry Rich Nourishing Day Cream

    Snowberry Rich Nourishing Day Cream ($96) is what it says it is, a rich and nourishing day cream that is absolutely jam packed with antioxidants, peptides and, of course, ceramide-3. Actually, ceramide features in many of Snowberry’s organic and natural products. There are plenty of peptides and botanicals. I like the inclusion of mycosoprin extract that protects the skin from UVA and environmental pollutants and superoxide dismutase that assists with the production of collagen, elastins, fibronectins, keratinocytes and hyaluronic acids. Snowberry says Rich Nourishing Day Cream boosts moisture by 39.64%.

  • Mad Hippie Exfoliating Serum

    Mad Hippie Exfoliating Serum ($35). Although the moniker is "exfoliating," this serum is an all-rounder. It exfoliates with lactic and glycolic acids, brightens with a botanical complex called Gigawhite, and rebuilds and repairs with the peptide Matrixyl 3000, apple stem cell, vitamin B in the form of niacinamide, and ceramide-3. Specifically, ceramide-3 protects the skin from trans‐epidermal water loss.

  • Skin Nutrition Cell CPR

    Skin Nutrition Cell CPR ($170&). This has got it all, including ceramide. Skin Nutrition's philosophy is that skin cells are complex things made up of phospholipids, proteins (enzymes, oligopeptides, amino acids, growth factors), oligosaccharides, oxygen, vitamins and minerals. And so, therefore is Cell CPR with a whopping 70 or so ingredients. Cell CPR has been a favorite of mine for more than three years now.

  • December 1, 2017

    by Christina

    My cousin and I both have rosacea. We both use Peter Thomas Roth Rose Stem cream and have been extremely happy with it. It has cermides. We both also use rosehip seed oil in addition to it, which is known to heal the skin.

    I've tried Cerave products and have been happy with them as well, although I prefer to use their facial sunscreen (also has ceramides in it) and their hydrating cleanser. Their skin care products for the face just didn't do what I wanted for wrinkles, but it you are not worried about wrinkle correcion or evening your skin tone, their products will work fine.

  • February 12, 2015

    by mari

    cerave cream (not the lotions) is the only thing I can use during the day that does not sting, irritate, and that moisturizes my skin. I just do not like all the chemical sounding ingredients. I've been looking for something less chemical but not full of actives that irritate me during the day (vit c, retinols, AHAs, crazy sounding extracts, essential oils etc) but no luck! I can do those at night only sense I've got a UV/electrosensitive disorder and these things react in skin when exposed to any UV light - within minutes my skin is inflammed. At night, no problems. So frustrating. I hope I find something one day.

  • April 29, 2014

    by Shirley

    I just went to and bought the active ingredient... a whole whopping bottle for way cheaper then mixed it into cream base such as acqueous lotion. Way more economical.

    As a person with eczema for the last 30 years of my life and living with flaky skin all the time I say it is quite effective.

  • September 12, 2013

    by Joe

    I thought I read somewhere in TIA about it being iffy about taking oral phytoceramides. So, since they're not terribly expensive and I've wasted more money on less I thought I'd give it a shot. I've seen a difference in my skin in 6 weeks, mostly however "color"- not like tan but naturally colorful skin--- it's the only difference in skin care. Now the only other thing I think I should disclose is that I have congestive heart failure and have to take diuretic pills during the day. I heard phytoceramides help keep moisture in skin thought I'd try it. Five people who haven't seen me in months said your color is back (and I
    Never go in the sun. Just thought I'd share this (I also take multis and extra biotin but have been taking these for years).

  • August 13, 2013

    by Cam

    What are your thoughts on Cerave lotion? It's inexpensive and seems to have helped my skin, soothing it and reducing my rosacea symptoms.

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