Reviewed by Ageless Jen

After being selected as a product tester for Hyalogics' Episilk FRS serum ($34 for 1 oz) I was quite optimistic about the results I would undoubtedly experience.  With the key ingredients being hyaluronic acid, Argireline, aloe vera juice & even echinacea, I eagerly anticipated seeing the anti-wrinkling benefits of Argireline on my crows eyes & dimple line. The dimple on my cheek, which always used to earn compliments, has started extending itself into a line, down my face & under my chin!

Since aloe vera contains peptides, vitamins & minerals & is well known as a treatment for burns, I figured I would see the added benefit of some redness reduction, caused by a few broken blood vessels on one of my cheeks.  Same goes with the echinacea, which I have frequently used as an immune support, oral supplement, when feeling less than healthy, with great results.

The first week I used it, happened to coincide with a ski trip to Colorado, where the elevation was significantly higher (6,000-8,000 ft) than normal for me...and drier.  Needless to say, I saw NO changes in the wrinkles after that week, but I gave it the benefit of the doubt, based on the environmental changes I described.  I did notice that my skin didn't get as dry & flaky as it normally does after several days of skiing, which I attributed to the added moisture from the hyaluronate acid & aloe vera juice.

It has now been 4 weeks, and, alas, my crows eyes are just as "deep" as when I started & the dimple still has a line attached, like the rock chip on a window shield that has started to morph into a crack.

I decided to do some additional research on Argireline (acetyl hexapeptide-8), an anti-wrinkle peptide, trademarked by the biotech company, Lipotec. According to the company brochure, Argireline is effective against the development of skin wrinkling, which is accomplished by attenuating muscle contraction (sort of like Botox).  The problem in my case, is that the cat is already out of the bag, so prevention can only go so far at this point.  The studies summarized in the brochure, used either a 5 or 10% solution of this peptide, with impressive results.  I have no idea what percentage of Argireline solution is in this serum, but, based on the reduction of wrinkle depth I did NOT experience, my guess is that it's less than what was studied.

An additional observation I made after week 3 of using the FRS Serum, is that it started flaking where it was applied, which is particularly annoying when trying to apply makeup.

I decided to stop using the serum after 4 weeks, although I still have half a bottle left. I'm going to give it to my sister to try.  If her results differ from mine, I will certainly provide her feedback. As for me, I will continue my search for the perfect serum!


Water, Argireline, Glycerin, Hyaluronic Acid, Polysorbate 20, Xanthan Gum, Triethanolamine, Aloe Vera Juice, Lactoperoxidase, Glucose Oxidase, Glucose, Wheat Extract, Asian Ginseng, Echinacea.