Jan Marini's products are never dull, usually work and always push the boundaries of new discoveries in the lab. Sometimes this results in controversy (as with Age Intervention Eyelash Conditioner). Her latest product, on sale for the first time this week, is an acne cream for aging skin called Transitions and it looks as if it will live up to Marini's reputation.

Acne treatment and anti-aging are hard to combine because  acne treatments such as benzoyle peroxide are very drying. Age Intervention Transitions Face Lotion has two ingredients for treating acne: a 1.0% concentration salicylic acid, which is a beta hydroxy acid that sloughs off skin and prevents pores from clogging; and spironolactone, which is used to treat acne and hair loss.  Usually it is taken orally (and there are some trials on rats that suggest it could be carcinogenic). Topical spironolactone has mixed reviews from acne sufferers - some say it works fabulously well, others seem to get side effects of pimples and cysts.

In a cream that thinks of everything, there are an anti-inflammatory ingredient, an antiseptic and arnica. On the anti-aging front, there are anti-oxidants such as green tea, vitamin E and omegas 6 and 3.

Most interesting of all is the use of something called creatine. When creatine naturally occurs in the body, it sends energy to muscles and nerve cells. It is believed that it encourages production of human growth hormone. Usually it is taken orally by bodybuilders. I am not sure what its purpose is in Jan Marini's Transitions, but I predict that we will see creatine cropping up in other products.