Free shipping on all orders over $39

Medik8 Growth Factor 1.0 oz

Medik8 Growth Factor- reviewed and recommended

Reviewed by Marta June 22, 2013 29 Comments


Synthetically produced EGF noticeably alleviates wrinkles


Phenoxyethanol and Yellow 5 are possible irritants
The peptides in this serum really deliver anti-aging results

One of the more intriguing stem cell extracts is the peptide sh-Oligopeptide-1. It is  in a serum that I have been testing and have been impressed by, Medik8 Growth Factor Youth Activating Serum (1oz/$160). Initially it rang a bell as it has the same name as the barley-derived epidermal growth factor used in BioEffect, the serum from Iceland and one of our Five Best with Plant Stem Cells. But it turns out it is a little different.

Thanks to some clarification from Medik8, I now understand that Medik8's EGF is bioidentical to human EGF, but synthetically produced - hence, the pre-fix SH (synthetic human) rather than RH (recombitant human). Medik8 claims that its EGF is more potent than barley-derived ones - based on personal use, I would agree with that - and it is triple filtered for extra purity.

There are several things to like about Medik8 Growth Factor. It has a pared back formula that has no solvents, alcohols or other ingredients that could negatively impact the growth factor. The price for a 1oz bottle is very good compared to BioEffect. The serum is light, absorbs easily and does not leave a sticky residue. And, oh yes, it works. I found that it has a good effect on wrinkles – even those forehead ones - and a very noticeable lifting and tightening.

There isn’t any independent research that I have found on this active and its results. However, my experience with it has been positive with an effect on wrinkles. It must be said that I gave my test six weeks and although I felt my skin was smoother within a couple of weeks, as with most growth factors, I found that the serum came into its own after a month or so.

The handful of accompanying actives are all useful. There is antioxidant rosemary, panthenol (vitamin B) and hydrating hyaluronic acid. The only thing not to like is the preservative phenoxyethanol, which may be a neurotoxin and irritant. Note that the coloring Blue 1 is deemed safe for use in the EU and by the FDA. Yellow 5 (C1 19140) is a tartrazine and although it is commonly and legally used, it can cause allergic reactions in some people.

I first came across Medik8 a few years ago with a product called Firewall and as this European brand didn’t have much presence in the US, it went off my radar. I am pleased to have been reunited with it and look forward to trying some more of Medik8 products as well as hearing more from our reviewer Noel on progress with the Firma Derma neck serum.

Ingredients: Water, Rosemary extract, Panthenol, Hyaluronic Acid, Hydroxypropyl Methylcellulose, sh-Oligopeptide-1, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Sodium Citrate, Lecthin, Blue 1 (CI 42090), Yellow 5 (CI 19140)

  • July 5, 2015

    by Regina

    For this price, at least they could make a product that's USDA Organic. And free of synthetics. Also, it's unclear if they use animal ingredients (toxic production), or animal testing. I'll just stick to my coconut oil for now...

  • May 10, 2015

    by Polina

    Hi, I've been looking for a good serum to improve my skin but am not sure if this will work for me since it's got citric acid. My skin is very sensitive and allergic to Vitamin C. But I still decided to try it out and ordered a travel size. We'll see how it'll do. ;)

  • September 10, 2014

    by julie

    I have been trying a few different serums and exfoliators over the past few months and this product was one. I had a sample which I used for about 10 days. When I ran out I did not buy a full size because of the cost . ( I have a kid in college and the budget to show it!) Well, within a few days I noticed a difference in my skin - it did not look as pretty, smooth, radiant- and now I have to break it to the husband that I need a full size bottle of this.

  • July 19, 2013

    by Marta

    Hi Shalini

    It isn't an issue of age, but of wrinkles. Growth factors and some peptides need something to repair - eg a wrinkle (different peptides do different things: If you don't have wrinkles then you won't see any results and will be disappointed. If you are looking for something preventative, choose a product with antioxidants. See our post on products with the most powerful antioxidants:

    Try looking at our suggested regimen for 30-somethings:
    Or if you do feel that you are seeing signs of aging then there is the 40-something regimen:

  • July 19, 2013

    by Shalini

    Hi Marta. I am 35 with acne prone combo skin. I have been a retinol user for a while and recently switched to a peptide regime (Arcona firming serum). I have been eyeing the Medik8 growth factor for sometime. However, I was wanting to understand the difference between growth factors and peptide serums?
    Is it that growth factors are recommended for 40+ only?
    How are the two different in terms of promoting collagen?
    I understand peptides are more preventive than reparative.
    Please advise if I could include a growth factor along with a peptide serum.
    Thank you!

Join the discussion! Leave a comment below.

My Comment

Add a comment...

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More