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Nerium AD Night Cream

Nerium AD Night Cream Review

Reviewed by Marta February 6, 2013 99 Comments


Not much but at least there is quinoa


The active ingredient is a poisonous plant
Ineffective and caused skin breakouts

Nerium AD Night Cream ($110) is a curious product that after a month of testing I find to be ultimately unpleasant, ineffective and puzzling.

The active ingredient is the poisonous leaf of the oleander plant. It is so poisonous that, as I wrote at the beginning of October, just one leaf can kill a child. It is listed as the second ingredient in Nerium AD Night Cream. I have lived to tell the tale, but my skin did break out when I applied Nerium AD. I had more false starts than a learner driver with this cream as I had to repeatedly stop using it in order to let my skin calm down.

Indeed, skin irritation from contact with oleander has been documented and “allergies are possible” (source). Several people commented on my Nerium oleander article with reports of their own allergic reactions. To be fair, my reactions seemed to stop after about two and half weeks. Perhaps my skin got used to it.

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Nonetheless, I never was won over by Nerium. I don’t like the smell (compost) or the thick, almost clay-like texture. It did absolutely nothing for my skin, no fading of wrinkles nor improvement of the complexion.  As mentioned in the previous article, I haven’t found any independent information confirming that nerium oleander works for skin anti-aging.

The texture of Nerium Night Cream leads me to one of the puzzling aspects of the formula as set out by the ingredients list on the bottle and the package. There is no base listed – typically this would be water or oil. The first ingredients are the proprietary blend of nerium oleander followed by something called “proprietary protein,” which includes collagen. Only then comes rice bran oil.

The rest of the formula is fairly lack luster (apart from quinoa). The third so-called “proprietary blend” amusingly includes phenylpropanol, which is routinely prescribed for incontinent dogs. Here it is part of a complex used for stabilizing cosmetics.

For some recommended alternatives, see Five Best Anti-aging Serums, Five Best with Growth Factors, Five Best for sagging skin.

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  • February 19, 2016

    by Beth

    I have been using it for almost a month. Both sides of the nose pieces on my eyeglasses turned green.

  • April 9, 2015

    by Shannon

    I love these products!! Mariana, you can only get the products from a representative. Most of us are just working individuals who have fallen in love with the products and want to share with others. I researched the products a TON before I got involved. And, I think many people are very misinformed about what it is all about and how that compares to other skin care products that are on the market. But, that's ok. It takes time for people to accept new things!! Of course I would be willing to send you a sample, but if you have someone you know who is a rep you should probably contact them!! :) Hope you have an amazing day!

  • April 8, 2015

    by mariana

    Hey, I would love to test this Nerium AD, it is possible that you could send a test tube

  • February 10, 2015

    by Gillian

    I started researching this product, having just met a rep. When I heard the word oleander, an alert went off in my head and I had to hold my tongue. I make and sell creams and lotions on a small scale, and I can tell you that there is something wrong with the label as presented here: the ingredients must be in descending order by weight. In a cream, you would expect water or a water substitute to be the first ingredient, but I don't see this, unless it is the Aloe Vera. Proteins are usually added at about 1% of the product, so their listing high up is problematic. I would expect to see emulsifiers and thickeners in the 2 - 5 % range, but they are listed lower down. Oils should be up to about 10- 15% in total, and yet they are low down too. This label clearly is not complaint in the order of the ingredients.

    My big question is, knowing the toxicity of oleander, was this extract ever approved for topical use by the FDA? I'll have to check around to see what I can find.

    I've read elsewhere that the percentage of the active ingredient oleander extract is actually less than 1%, but since the company is very secretive about their formula, that is conjecture. If that is the case, it is far more likely that the miraculous results are because of the Aloe Vera.

  • February 2, 2015

    by Christine

    I have been approached to carry this product in my store more than 3 times and each time I explain to people that it will NEVER make it to my shelf.

    Here's some great links that might help you make the decision about whether you'd want it on your skin. I especially caution people who have young children; the plant is toxic. Check out the link provided proving that. Money is a great motivator....but it shouldn't be the reason to peddle a product whose supposed "testing" remains unpublished.

    The first is about the ingredient Phenylpropanol

    This one is an actual published medical article relating to the plant:

    Those are just 2 sites about 2 ingredients. Don't even get me started on proprietary blends and parfum!

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