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Nioxin for hair growth- tested and rejected

Is a Solution for:
Thinning Hair & Shedding
October 19, 2009 Reviewed by Marta 10 Comments
For the past five or six weeks, I have been testing Nioxin Intensive Therapy Follicle Booster ($20) in a side by side comparison with Folligen Cream ($17.99) - Folligen on my right temple, Nioxin on the left. Nioxin provided results very quickly, two weeks into my test, Nioxin has produced noticeable new hair growth. But the hairs were the merest wisps and a month later they still are. I've seen newborns with a more impressive thatch.

In my experience, Folligen takes at least a month before anything happens, but when hair starts to grow it is proper, thick hair. Furthermore, I used the Nioxin every day and the Folligen only about three times a week. Folligen also works on eyelashes and eyebrows, so all in all is much better value.

Nioxin relies on two ingredients phospholipids and saw palmetto. There is research to back up phospholipids as meriting a role in the hair regrowth department. Fairly recently, scientists discovered that phospholipids play an important role in cellular regulation. A Japanese study shows that phosphatidic acid has an “intensive” effect on hair growth by targeting the epithelial cells and epidermal keratinocytes. Furthermore, it induces the anagen (growth) phase of the hair cycle, perhaps by having a protective action on transforming-growth-factor-beta1-induced apoptosis.

Although saw palmetto is commonly used for hair regrowth, no one is sure how it works and there isn’t any convincing research, but it’s believed that it may block an enzyme (5-alpha-reductase) from allowing the hormone testosterone from being converted to another hormone, dihydrotestosterone.

Folligen’s active ingredient is copper peptides. Copper is a wound healer and its ability to assist in hair growth was discovered when it was noticed that the hair follicles around treated wounds were exceptionally large. It seems to work on the follicle in two ways: increasing follicle cell proliferation increased follicle size; and copper also decreases programmed follicle cell death, which results in smaller follicles.

Over the coming weeks, I'll be testing Osmotics FNS. I already like the FNS shampoo and conditioner and I'm eager to see how the growth serum turns out.

Ingredients in Folligen Cream

Purified water, copper peptides (hydrolyzed soy protein and copper chloride), squalane, glyceryl stearate, PEG-100 stearate, ethylhexyl palmitate, stearic acid, cetyl alcohol, cupric chloride, propylene glycol (and) diazolidinyl urea (and) methylparaben (and) propylparaben, allantoin, tocophersolan (Vitamin E), menthol, lavandula augustifolia (lavender) oil, fragrance, mixed (alpha, beta, gamma, delta) tocopherols.

Ingredients in Nioxin

Water (Aqua), Phospholipids, Hydrolyzed Algin, Saccharomyces Lysate Extract, Propylene Glycol, Ginkgo Biloba, Humulus Lupulus, Panax Ginseng, Serenoa Serrulata, Silybum Maranium, Wheat Amino Acids, Soy Amino Acids, Ethoxydiglycol, Coenzyme A, Coenzyme B5, Coenzyme B6, Coenzyme B12, Coenzyme Biotin, Coenzyme Folate, Coenzyme Nicotinate, Coenzyme Q6-10, Coenzyme R, Coenzyme Riboflavin, Coenzyme Thiamine, Panthenol, PEG-12 Dimethicone, Acetamide MEA, Tocopheryl Nicotinate, Hydrolyzed Keratin, Saccharomyces/Silicon Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Zinc Ferment, Mentha Piperita, Rosmarinus Officinalis, Swertia Japonica, Polysorbate-60, Polysorbate-80, Diazolidinyl Urea, Methylparaben, Propylparaben, Triethanolamine, Sodium Acrylates/C10-30 Alkyl Acrylates Crosspolymer, Methyl Nicotinate, Parfum (Fragrance).
  • January 4, 2015

    by Hema

    I'm very grateful to the Nixon hair loss treatment as my aunt has gained her hair back in much better position. I'm also going to try this hair loss products ad I have thinning hair specially at the front part of my head and, its has taken my confidence away. I have very complex medical history which includes - kidney transplant, daibetes, stroke and I'm on heavy medication daily. But after looking at my auntie's hair result I also like to give a try with hope of having a good and positive results. I like to give feed back after the use.Thanks

  • December 5, 2012

    by Julia

    Nizoral shampoo with the active ingredient ketaconazole is supposed to help keep hair from falling out due to DHT. Ketaconazole,also
    is believed to speed up hair growth.Hair forums on the internet are filled with women who have been using this for a while and swear by it.Some also use miconazole nitrate,which is the active ingredient in yeast infection creams.

    My personal experience with Nizoral,is that my hair is thicker with use and grows faster then normal.
    Nioxin is good for helping thing hair appear thicker,but I don't know if it really helps with hair growth.

  • March 27, 2011

    by angela

    is nioxin or folligen compatible with keratin treatment

  • January 1, 2010

    by Bill

    "produced noticeable new hair growth" ... Hi, I'm sorry to point this out but Nioxin doesn't advertise for new hair growth; the point of it is to provide a better scalp environment (among other things) for the current hair to thrive, thus giving a fuller-looking head of hair. If the scalp and hair are healthier then hair you already have will also stay in the scalp for longer and not drop out until the maximum time in to the life cycle of a hair.
    I've seen friends use various products to try and help and Nioxin has produced beneficial results for all of them as an overall effect, and quickly. More drastic products that actually target hair growth can work in some ways but not so consistently or reliably. Also, several of the more medicated ones produce some nasty side effects in some people.
    It's all down to preference at the end of the day, but thought I should add what Nioxin is actually advertised for doing; which is something I and many others have found it does very well.

  • November 22, 2009

    by marta

    Alison you signed up on October 23. You were sent an email at the time and you are required to answer it so confirm that you want to subscribe.

  • November 20, 2009

    by alison garcia

    please sign me up for your newsletter for "all things hair.



  • October 28, 2009

    by Jaysie

    Marta - Thanks for your reply. I opted for the serum because when I tried Skin Bio creams a few years ago, they were too rich and clogged my pores which are rather small. The actives in the serum are the about the same as the Folligen Cream. Maybe my follicles have changed with age - :/

  • October 25, 2009

    by marta


    My hair is growing completely normally and I haven't heard of your issue before. But I am not using Skin Biology Copper Serum. I am using Folligen Cream (same company but their hair line).

  • October 24, 2009

    by Jaysie

    I've been using Skin Bio's Copper Serum to regrow some sparse areas on my eyebrows. Yes, I've had new hairs sprout, but they don't want to lay down. Marta, is your new temple hair from the Folligen growing in a normal direction or has it grown in standing straight up? This has become a weird dilemma for me.

  • October 21, 2009

    by 2GM


    So which one would you recommend for thinning hair to boost hair regrowth?
    Nioxin starter kit or Folligen Cream.
    Please advise.

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