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Origins Plantscription Anti-aging Serum

Is a Solution for:
Sagging Skin
July 15, 2011 Reviewed by Marta 8 Comments
As I look at Origins Plantscription Anti-aging Serum ($55) I feel a little overwhelmed by more than 50 ingredients and a little disappointed that the third most dominant is a silicone. Most of the formula is, however, made up of plant extracts, of which the leading role goes to the extract from the bark of a tree called anogeissus latifolia.

According to Origins, anogeissus latifolia is nothing short of miraculous when it comes to eliminating wrinkles and restoring “bounce” to sagging skin. I looked into it and the tree, known as dhaora in India, contains large amounts of tannin and is used for tanning leather. In West Africa, the bark is used to treat skin disorders.

There is a fair bit of research into the components of anogeissus, mostly because it has proved to be a really good anti-bacterial that stops the spread of infectious skin diseases. Useful, but that doesn’t make it an anti-ager. The bark contains nearly no flavonoids (the typical plant-based antioxidants) but is rich in derivatives of ellagic acid. These derivatives are good antioxidants acting as scavengers of free radicals and as protectors of DNA from injury by alkylating agents. What’s more they are anti-inflammatory and research has shown that the ellagic acid derivatives inhibit enzymes that degrade collagen.

So it looks as if Origins might be on to something.  But they aren’t the only ones, Givenchy uses anogeissus, as does Jurlique. This might be why Origins has gone further by claiming that, working the University of Strasbourg, they discovered that anogeissus bark increases the skin’s fibrillin – hence the anti-sagging. I haven’t been able to find a published version of this research.

Many of the other botanicals in Origins Plantscription are oils and I do find the texture of this serum a little oily. Plus there is lavender oil in a relatively high concentration as well as a separate listing for linalool, lavender’s potentially carcinogenic component. Amongst the extracts there is hibiscus abelmoschus, which is mostly used for its musky smell and sapindus mukurossi, typically used to make soap. There seems to be some evidence that guava is antioxidant, but there isn’t a whole lot of research on it. Nor is there for sigesbeckia orientalis (St Paul’s wort). One of the most convincing is polygonum cuspidatum (Japanese knotweed) contains antioxidant resveratrol.

The only peptide here, the expression line controlling acetyl hexapeptide-8 seems a little of tokenistic throw-in way down towards the end of the ingredients list, along with sodium hyaluronate.

Origins promises that in four weeks Plantscriptions will visibly repair the four signs of aging. We shall see. I’ll report back in a month or so.


Water/aqua/eue, butylene glycol, dimethicone, glycerin, jojoba esters, anogeissus leiocarpus bark extract, rosa damascena flower oil, lavandula angustifolia (lavender) oil, pelargonium graveolens flower oil, illicium verum (anise) oil, citrus aurantium bergamia (bergamot oil), carthamus tinctorius (safflower) seed oil, myristica fragrans (nutmeg) kernel oil, citrus aurantium dulcis (orange) oil, citrus nobilis (mandarin orange) peel oil, citrus medica limonum (lemon) peel oil, litsea cubeba fruit oil, hibiscus abelmoschus extract, geraniol, linalool, cintronellol, limogene, sigesbeckia orientalis extract, prunus amygdalus dulcis (sweet almond) seed extract, mangifera indica (mango) leaf extract, psidium guajava (guava) fruit extract, polygonum cuspidatum root extract, centaurium erythraea (centuary) extract, sapindus mukurossi fruit extract, micrococcus lysate, rosmarinus officinalis (rosemary) extract, cucumis sativus (cucumber) fruit extract, pyrus malus (apple) fruit extract, scutellaria baicalensis root extract, salicyclic acid, phytosphingosine, glycyrrhetinic acid, sodium hyaluronate, phospholipids, acetyl hexapeptide-8, caesalpinia spinosa gum, methyl trimethicone, zinc pca, caffeine, ammonium acryloyldimethyltaurate/vp copolymer, arginine, caprylyl glycol, tetrahexyldecyl ascorbate, polysilicone-11, hexylene glycol, dicaprylyl carbonate, tromethamine, tocopheryl acetate, carbomer, silica, phenoxyethanol
  • September 24, 2016

    by Robin

    After 36 hours using this serum I broke out in a horrible rash and hives on my neck and face. Just started a 5 day steroid pack from Dr as I am disfigured from the swelling and redness.

  • January 20, 2015

    by Klara

    After second time using this product I also got some sort of alergic reaction
    My face is covered in rash and it does not seems to go away!! Will not use this product again

  • May 9, 2014

    by Ann Baker

    I broke out in hives after using this product, so I'm taking the ingredients to the allergist with me to determine which one I am allergic to. I am guessing it's one of the essential oils. Although I have had similar cosmetic allergic reactions in the past, interestingly, it's always the more expensive "department store" cosmetics and not the cheap everyday drugstore brands. I'm not sure why this is, but needless to say I will not be using this product anymore and encourage anyone with allergies or sensitive skin to do a patch test before using.

  • February 3, 2014

    by Christine

    Hi again,

    I just realized I made a few typos in my original comment. Darn small Kindle...hard to see what I have typed without my reading glasses.

    I meant to say Anogeissus Leiocarpus Bark Extract.

    I would really appreciate your input, as I stated in my last comment at your earliest convenience.


  • February 3, 2014

    by Christine

    HI Marta,
    I have been doing a bit of research on Anogiusses and the link to it having the capability to cause fibrillin production in the skin. I recently came across a patent that was approved on September 27, 2012 by 2 inventors, Declorq and Daly that show this Origins product fulfills all criteria for a successful anti-aging product. Also, I did find the Strasbourg I information you had not located at the time this article was written. I will enclose the link at the end of this comment. I would be very appreciative to hear your input as I have read mostly all positive reviews elsewhere and am myself interested in this product as well as their new lifting cream. Thanks!

    Here is the link:

  • January 12, 2012

    by Heather

    I finished my bottle today and had no results.

  • August 27, 2011

    by Marta

    Hi Susan, I completely agree with every word. It is very pleasant to use but proved to be pointless. I gave up on it after about seven weeks.

  • August 27, 2011

    by Susan

    This product was pleasant to use. It was almost odorless, non-greasy, and easily absorbed into the skin. Alas, I used the whole
    bottle and did not see any difference in the
    crepiness or discolorations on my neck.

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