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Osmosis Catalyst for skin renewal

Is a Solution for:
Eyelashes & Brows, Sagging Skin
Reviewed by Marta January 14, 2010 9 Comments
A corrected version of this article follows as we have been informed by a representative for Osmosis that the Catalyst may help stimulate the growth of eyelashes; however, it was not designed for application to eyelashes and is not advertised as a product for eyelash growth.

Osmosis, makers of Replenish (a serum that was one of Truth In Aging's best products of 2009), has just launched an antiaging face serum called Catalyst.

At $160 against Replenish's $38, Catalyst doesn't fall into the keen as mustard price category. Still if it does all it is cracked up to do.... which supposedly includes capillary repair, pigmentation reduction, wrinkle smoothing, sun protection and, last but not least, eyelash growth (though Osmosis does not advertise this benefit).

As always with Osmosis, the ingredients list is mercifully short. The main ingredient is calcium ascorbate. A salt of ascorbic acid, it plays an essential nutrient that plays a pivotal role in the body’s collagen production, tissue repair, synthesis of neurotransmitters and resistance to infection. This ingredient mainly functions as an antioxidant in cosmetic products. It has many anti-aging benefits including building collagen, defending the skin against free-radicals, healing inflammations, reducing the appearance of fine lines & wrinkles and lightening discoloration.

There are a handful of amino acids, including proline. This is an important amino acid that can typically be found in energy drinks. Obviously it works a bit different when applied to the skin. Here, D-proline helps strengthen the cell envelope and skin, and is involved in the body’s production of collagen and cartilage.

Catalyst's claims of sun protection could be met by glucosyl hesperidin. The flavonoid compounds in glucosyl hesperidin are known to provide antioxidant, UV absorbing, and radical scavenging benefits, and are also known to be effective in strengthening collagen structure. Its high solubility is also favorable for use in skin care products.

Eyelash growth may be prompted by keratinocyte growth factor (the main active in Skin Active's eyelash growth product). This is a protein in humans that is encoded by the FGF7 gene. Studies on mice suggest that this gene is responsible for hair development.

I haven't tried this yet, but it looks very tempting (despite the dash of potentially toxic phenoxyethanol).


Water, Calcium Ascorbate, Alchohol Denate, Proline, Glycine, Glycerin, Lysine HCL, Glucosyl Hesperidin, Zinc Gluconate, Citric Acid, Phenoxyethanol, Copper Gluconate, Silica, Clear Purified water, enhanced with the following frequencies: Fibroblast Growth Factor, Keratinocyte Growth Factor, Oxygen, ATP, Antibacterial
  • July 21, 2010

    by Ruby

    I am an esthetician in Portland and have just started carrying this product in the last couple of months. I have been looking all through my literature and have found absolutely nothing that says that it stimulates eyelash growth (maybe I am missing something?).

    I don't know who is charging $180 a bottle. But I charge $120. Someone is marking it waaaay up.

    I haven't carried it that long, but I used it on myself for over a month and really liked the results. I have pretty good skin already, but the main thing I notices the improvement in was my skin's texture and hyperpigmentation (usually nothing works for me).

    Please note though, Catalyst is meant to be mixed with an Osmosis Serum, it is preferable that you don't use it by itself. It does tingle when you put it on, but not that much. I actually think it feels great. You may be using other products that are sensitizing your skin if you are actually experiencing pain from catalyst.

  • June 24, 2010

    by kim

    How do you apply to the eyelashes?

  • May 21, 2010

    by Stephanie

    I just found the companion article- so no need to respond to my question.

  • May 21, 2010

    by Stephanie

    What were your findings re Catalyst? Did it do anything for your eyelashes? Was it more effective than replenish?


  • January 30, 2010

    by marta

    I am going to meet and interview the doctor behind Osmosis in a few weeks and will be a guinea pig (hopefully not a hairy one) by trying the product. More to come.

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