What is it? Osmotics Lipofill is a serum that increases facial volume by increasing the natural renewal of subcutaneous fat to plump and fill troubled areas while restoring firmness and tone.

For people with: Loss of volume on hands, neck, face and the labial nasals.

Recommended use: After cleansing, apply to targeted areas and allow serum to absorb for a few minutes. May be used on face, neck and hands. Use twice daily.

TIA recommends for people in: 50s+

Highlights: Marta saw an improvement in her skin; it was plumper and a small groove at the corner of her mouth diminished. To test if the effects were temporary, Marta stopped using Lipofill for a week. She was pleased that they did seem to last. She now uses it regularly with Baby Quasar, the at-home LED device.


Sarah said, I’ve been trying this cream twice a day now for the past 3 days and haven’t noticed any difference in the appearance of my nasal lines. I will keep trying as I desperately need something to work before I turn into Pinocchio.”

Ingredients we love: Sodium hyaluronate and saccharide isomerate are responsible for plumping. Saccharide isomerate works as a moisture regulator by binding to the free amino groups of lysine in the keratin of the outer layer of the epidermis. Some effective antiagers include artemisia abrotanum, known as wormwood, which contains four flavenols with spasmolytic activities. Spasmolytic is a type of muscle relaxer and so could be playing a role here as a kind of natural Botox. Another ingredient, which is at the forefront of the product, is rye seed. Rye seed is rich in arabinoxlyans and the extract is said to act as an internal tensor, boosting the skin’s abilities to firm and lift. Collagen boosting peptide power is provided by Matrixyl (palmitoyl oligopeptide) and tripeptide 1.

Ingredients we don’t: n/a

Retail Price: $85

More in TIA:

Osmotics Lipofill plumps marionette lines

Lips, jaw line and marionette lines

Marionette line solutions without fillers

Osmotics Lipofill for loss of volume

Bottom line: We recommend Osmotics Lipofill as an effective plumper and volumizer that seems to have more than just short term effects. And it is one of a few products that can get rid of pesky puppet and/or marionette lines!


Purified water, caprylic/capric triglyceride, rye seed extract, butylene glycol, artemisia abrotanum extract, isohexadecane, BIS-PEG/PPG-14/14 Dimethicone, ethylene/propylene/styrene copolymer, cyclopentasiloxane, sodium hyaluronate, xanthan gum, tripeptide-1, saccharide isomerate, ethylhexyl palmitate, tribehenin, sorbitan isostearate, palmitoyl oligopeptide, oat kernel, squalane, stearic acid, glycerol stearate, cetyl alcohol, dimethicone, PEG-100 stearate, tocopheryl acetate (vitamin E), ascorbic acid (vitamin C), carbomer, disodium EDTA, diazolidinyl urea, iodopropynyl butylcarbamate, tromethamine.

Please add your comments, questions and share your experience in the comments section