My grandfather told me to always be thankful when something good happened, but to be aware that not everything is as it seems… all the time. Well, that’s what I feel about Planet Skincare’s Wrinkle Defence Moisturiser With Syn-ake (about $100). When I was asked to review Planet Skincare’s Wrinkle Defence, I didn’t know what it was, hadn’t heard of it before, but I’m game for just about anything. Then when I found out that its main ingredient, Syn-ake, is a synthetic substance, which mimics part of a polypeptide found in the venom of the Temple Viper, I started to rethink my commitment rapidly. So I investigated a little bit more, and I wasn’t exactly thrilled by what I was finding out.

The product is touted as an anti-aging moisturizer and its main ingredient, Syn-ake (dipeptide diaminobutyroyl benzylamide diacetate) is a muscle-relaxing peptide that mimics the activity of Waglerin 1, a peptide that is found in the venom of the Temple Viper. Anyway, Syn-ake is said to inhibit the neuromuscular communication that blocks the message the brain sends to the facial muscles, thereby reducing or restricting, depends on what side of the line you’re on, facial mobility so that wrinkles do not continue to form. Sounded kinda paralytic to me, but I said I would try it….

It has been compared to Botox, but unlike Botox which takes affect almost immediately, Planet Skincare’s Wrinkle Defence has an accumulative effect with results seen sometimes after 10 to 15 days. Well, that wasn’t the case for me. Moving on, wrinkles are said to be visibly reduced, and the skin is supposedly left healthy and glowing with renewed hydration. Okay, I thought, I’m in need of that. Additionally, Planet Skincare claims that the product visibly reduces wrinkles by 52% and has an 82% smoothing effect on the skin; overall, reducing fine lines and wrinkles dramatically within 28 days. Papa also said, if it sounds too good to be true....

So I incorporated the Wrinkle Defence into my daily regimen, and the first thing I noticed was that the smell is absolutely wonderful. It is quite pleasant and appealing to the senses, and it grows on you each time you apply it. Secondly, it moisturizes quite well and does not require a lot of product to do so. And I didn’t notice that it inhibited any movement of my face while applying it day or night. I followed the directions and used it twice daily on my face and neck and slithered it – er, slathered it on where I really needed it as I wanted to see some quick results (along my darlin’ laugh lines and a little crinkle I’ve noticed beginning to form just under my chin). I also used it with my LED red light three times a week as an added impetus for those little darlings as well.

Things went along well until the third weekend when I awoke one Saturday and was aghast that my face looked like it had aged on me overnight. I didn’t know why, and I played back the events of the night before and realized that I had used an over-the-counter product (Clean and Clear) for a slight breakout that had erupted from having some fine cheek hair removed, and the results floored me! And I was very afraid. The good news is that by that afternoon, all was well again, and I bravely washed my face a third time and again used the Wrinkle Defence to moisturize it and nothing happened. So I’m really unsure if there was just something in the product I used that reacted with the Syn-ake, causing it to tighten and pull my face – and not in a good way. By the next day, my face was absolutely glorious. I was so confused, and I wasn’t liking this confusion at all because despite the radiant aftermath I didn’t understand why the reaction happened and reading all the conflicting opinions online didn’t help. This was the only negative occurrence I experienced and I haven’t used the two products together again.

It’s been over 30 days now and I have to tell you, I am impressed, but I’m not kick-assed impressed, because I can’t honestly say it’s actually done what it says it will do within the 28-day timespan. My fine lines have not been reduced by 52% because if they had, they’d be gone, but they have been reduced. Nor can I fully attribute that Wrinkle Defence alone has helped with my facial smoothness (a little mini microdermabrasion and my LED were also in the mix). Perhaps I’m a hard sell at this point; I’ve tried so many of these products before and raved about them initially only to have them fall flat on me later, so I’m being cautious.

Suffice it to say, I do like what I’m seeing, and I’m cautiously optimistic that it is a good product despite its origin. I don’t know how I feel about using it long-term because of the Syn-ake, and for the price, I’m not ready to jump on the boat just yet. My laugh lines have decreased and the area under my chin does feel slightly firmer but I’m hesitant to say “go for it.” For me, the real results are still pending as I finish using it up, there’s still a nice amount of the product left that I plan on finishing it to see what happens. If it continues to do what I’m seeing, then I will slowly be won over by this little wrinkle-inhibiting product, but the jury is still out on whether I want to stay Syn-akey with it.

The product is free of parabens that can dry or irritate the skin, allergy tested, not tested on animals; and men and women of any age or skin type can use Planet Skincare.

Ingredients: Aqua, Rosa Damascena (rose) flower water, Dicaprylyl carbonate, Glycerine, Squalane, Myristyl mystrate, Steareth-21, butylene Glycolcety Alchohol, Dimethicone, Mangifera Indica (Mango) Butter, Passion incarnata (Passion) seed oil, Steareth-2, Stearyl alchohol, Stearic acid, Tocopheryl acetate, Panthenol, Sodium polyacrylate, Cycopentasiloxane, Phenoxyethanol, Dipeptide Diaminobutyroyl benzylamide diacetate (Syn-ake), fragrance (parfum), Simmonasia chinsis (jojoba) oil, Calendula officinalis (calendula) oil, Helianthus annu (sunflower) oil, Ethylhexylglycerin, Allantoin, Xamtham gum, 2-Bromo-2-Nitropropane-1, 2-Diolhexyl cinnamal, Linalool, Butylphenyl methylpropional, Citronellol, Alpha-Isomethyl ionone, Limonene