Syn-tacks may be the new anti-wrinkle peptide to give Matrixyl 3000 a run for its money. According the company that makes Syn-tacks, it stimulates a broad spectrum of things responsible for youthful skin - laminin V, collagen types IV, VII and XVII and integrin - all at once. It is relatively new on the cosmetic scene and can be found in not much more than a handful of leading edge products. Like Matrixyl 3000, Syn-tacks is made from two synthetic peptides, so look out for palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine and palmitoyl dipeptide-6 diaminohydroxybutyrate. I've rounded up a few potions with Syn-tacks that look promising. Do write in with any good finds that I've missed.

Arcona Peptide Firming Complex Regenerate AM/P ($72). This product by Arcona looks as if it could pack a powerful punch. Rarely have I seen so many peptides in one bottle. In addition to Syn-Tacks, there is Syn-Coll, a tripeptide and thymulen 4, a peptide that is supposed to boost the immune defenses. There is also epidermal growth factor and, for good measure, some pea extract. Arcona goes out of its way to avoid unpleasant things such as parabens so there doesn't seem to be anything to dislike.

M Lab Anti-aging Blemish Control ($175). M Lab's products always make me feel a little dizzy. In Anti-aging Blemish Control there is an ingredients list as long as your arm (I counted over 70) and our friend Syn-tacks is in there somewhere. The question I have with M Lab is whether so many goodies can be crammed into one bottle without minimizing the concentrations to the point where they can barely be effective. The M Lab philosophy is the ingredients are synergistic and combine together to do their magic. I remain a little skeptical, but we did have a positive reader review of an M Lab product.

The other problem with there being so much stuff is that it is easy to overlook the ingredients that I'd rather not come into too much contact with: sodium benzoate (which kills off DNA and is carcinogenic if it gets mixed up with vitamin C; plus chlorphenesin and phenoxyethanol (irritants and much worse if ingested).

Canyon Ranch Age Transforming Concentrate Serum ($150). The upmarket spa that is Canyon Ranch launched its anti-aging cosmetic line a few months ago. Its signature ingredient is niacin (vitamin B) that is time-released. But I was interested to see that Transforming Concentrate focuses on Syn-tacks and ceramides. Although Canyon Ranch's formulator isn't quite is manic as the one over at M Lab, there is a bit of a everything but the kitchen sink vibe going on here too. Still, there are plenty of good botanicals in the mix.

RTOV Intensive Facial Lift Stimulator ($48). As well as Syn-tacks, RTOV has added in a handful of other peptides. One of them, trylagen, is all about collagen. It stimulates collagen synthesis and it "organizes" the collagen, by which is meant that it uniforms their diameter and spaces them
regularly to make the skin more supple. This potion also has
pseudoalteromonas ferment extract. This is a strain of bacteria from the Antarctic and researchers in Barcelona say that it is exceptionally good at retaining moisture. The usual suspects in the preservative department, but otherwise this looks interesting.

Isomers Stem Genesis ($75). I must say that I am beginning to feel rather remiss for not having got better acquainted with Isomers. They make simple, intelligent products. The latest is Stem Genesis and this may be the one that I should get to know. Using a technology that was invented to cultivate apple stem cells, the ingredient called malus domestica fruit cell culture, is supposed to reduce the appearance of wrinkles in four weeks. There are a couple of vitamin Cs, tiger nut (for skin elasticity), an alga and the anti-radical tripeptide 10. Oh, and there's Syn-tacks

Ingredients in Arcona Peptide Complex

Aqua, Pisum Sativum (Pea) Extract, Hydrolyzed Myrtus Communis Leaf Extract, Dextran Complex, Acetyl
Tetrapeptide 2 (Thymulen 4 Pentapeptide), Palmitoyl Tripeptide 5 (SYN-Coll Tripeptide), Diamino Butyloylhydroxyehreonine (Syn-tacks Peptide),
Epidermal Growth Factor, Palmityol Dipeptide, L-Sodium Hyaluronate, Diaminohydroxytbutyrate, Mica.

Ingredients in M Lab Blemish Control

Aqua (Water), Montmorillonite, Glycerin, Argania Spinosa Kernel Extract, Pentylene Glycol, PPG-14 Butyl Ether, C12-15 Alkyl Ethylhexanoate, Butylene Glycol, PEG-40 Stearate, Cetearyl Alcohol, Sesamum Indicum (Sesame) Seed Extract, Serenoa Serrulata Fruit Extract, Squalane, Oligopeptide-10, Magnesium Aluminum Silicate, Caprylyl
Glycol, Cholesterol, Salicylic Acid, Xanthan Gum, PEG-60 Almond Glycerides, Chlorphenesin, Oleanolic Acid, Ceteth-10 Phosphate, Palmaria Palmata Extract, Dicetyl Phosphate, Nordihydroguaiaretic Acid, Vaccinium Myrtillus Fruit/Leaf Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Acer Saccharum (Sugar Maple) Extract, Saccharum Officinarum (Sugar Cane) Extract, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Carbomer, Citrus Aurantium Dulcis (Orange) Fruit Extract ,Citrus Medica Limonum (Lemon) Fruit Extract, 1,2-Hexanediol, Hydrolyzed Algin, Algae Extract, Artemisia Vulgaris Extract, Dimethylacrylamide / Acrylic Acid/Polystyrene Ethyl
Methacrylate Copolymer, Potassium Sorbate, Chlorella Vulgaris Extract, Sea Water (Maris Aqua), Urea, Sodium PCA, Disodium EDTA, Ubiquinone, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Hydroxypinacolone Retinoate, Retinyl Palmitate, Epilobium Fleischeri Extract, Phenoxyethanol, Polyquaternium-51, Trehalose, Sodium Benzoate, Boswellia Serrata Extract, Oryza Sativa (Rice) Bran Extract, Mel Extract, Methylisothiazolinone, Butylphenyl Methylpropional, Sodium Hyaluronate, Triacetin, Tropolone, Linalool, Alpha-Isomethyl Ionone, Amyl Cinnamal, Hexyl Cinnamal, Aspalathus Linearis Leaf Extract, Camellia Oleifera Leaf Extract, Citronellol, Limonene, Benzyl
Salicylate, Hydroxycitronellal, Geraniol,Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Fragrance (Parfum).

Ingredients in Canyon Ranch Age Transforming

Water (Aqua/Eau) ,Cyclopentasiloxane, Myristyl Nicotinate, Butylene Glycol, Glycerin, PPG-3 Benzyl Ether Myristate, PEG-40 Stearate, Soybean (Glycine Soja) Extract, Ethylene/Acrylic Acid Copolymer, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Dimethicone, Glyceryl Polymethacrylate, Silica, Isohexadecane,
Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Palmitoyl Dipeptide-6 Diaminohydroxybutyrate, Palmitoyl Oligopeptide, Ceramide 2, Hydrogenated Lecithin, Lycium Chinense Fruit Extract, Vaccinium, Angustifolium (Blueberry) Fruit Extract, Arctostaphylos Uva Ursi Leaf Extract, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sodium Hyaluronate, Lecithin, Hydrolyzed Wheat Gluten, Ceratonia Siliqua (Locust Bean) Gum, Aloe Barbadensis Leaf Juice, Triticum Vulgare (Wheat) Germ Extract, Saccharomyces Cerevisiae Extract, Cola Nitida
Seed Extract, Paullinia Cupana Seed Extract, Ilex Paraguariensis Leaf Extract, Panthenol, Caffeine, Octyldodecanol, Tocopheryl Acetate, Retinyl Palmitate, Arachidyl Propionate, Ethyl Linoleate, Ethyl Linolenate, Polysorbate 80, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Fragrance (Parfum), Aminomethyl Propanol, Chlorphenesin,
Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, 1,2-Hexanediol, Tropolone, Potassium Sorbate Benzyl Benzoate, Limonene, Hexyl Cinnamal, Butylphenyl Methylpropional Linalool.

Ingredients in RTOV

Aqua (Water), Argireline® (Acetyl Hexapeptide-8), Cetearyl Olivate (and) Sorbitan Olivate,C12-15 Alkyl Benzoate, Cetyl alcohol, Propylene Glycol USP, Trylagen™ PCB (Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Xanthan Gum, Carbomer, Triethanolamine, Phenoxyethanol, Butylene Glycol, Caprylyl Glycol),  Allantoin, Blackberry Seed Oil, Glycerin, Green Tea (Camellia Sinensis Leaf Extract), L-Ascorbic Acid (Vitamin C),Tocopheryl Acetate (Vitamin E), Syn®-Taks (Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate), Germall® Plus (Propylene Glycol (and) Diazolidinyl Urea (and) Iodopropynyl Butylcarbamate), Rosemary Oleoresin, Triethanolamine hanalomine.

Ingredients in Isomers Stem Genesis

Aqua/Water, Malus Domestica Fruit Cell Culture, Xanthan Gum, Glycerin, Lecithin, Tripeptide-10 Citrulline, Cyperus
Esculentus Tuber Extract, Erythritol, Homarine HCl, Acetyl Tetrapeptide-9, Ascorbyl Glucoside, Pamitoyl Dipeptide-5, Diaminobutyloyl Hydroxythreonine, Palmitoyl Dipeptide-6 Diaminohydroxybutyrate, Sodium Hyaluronate (LMW), Sodium Hyaluronate (HMW), Magnesium Ascorbyl Phosphate, Phenoxyethanol, Tropolone,
Carbomer, Triethanolamine.