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Telomeres were recently popularized - and legitimized - by a Nobel Prize winning team of scientists. Research on telomeres and aging has led to an ingredient called teprenone (sometimes marketed under the name of Renovage) cropping up in anti-aging potions and lotions.
So how do telomeres work? If DNA is broken there are two options after the cell cycle is stopped: Repair or death. If cells divided without telomeres, they would lose the end of their chromosomes, and the necessary information it contains. They are often described as being like the tips on the ends of shoelaces that stop them unraveling. Telomeres shorten every time a cell divides. When they become very short, they trigger cell crisis and cell death. As we know, cells can only replicate a limited number of times – a phenomena called the Hayflick Limit. There’s more on telomeres in an article posted last August.
In cosmetics, the objective not to lengthen the teleomeres, stabilize them so that at least they won’t shorten. Maintaining telomere length extends, we are told, the Hayflick Limit by one third. Renovage (made by the people behind Matrixyl) aims to do just that.
We have rounded up products that contain teprenone, ranging from cleansers to eye creams and body lotion. Some we have already covered on Truth In Aging, such as Skinn Wrinkle Night Balm, Jack Black's Protein Booster, YBF's new Boost. and Babor. There are also some new finds as well. Click on the images for details.
Ingredients In Jack Black Protein Booster Serum: Water, Glycerin, Sodium Polystyrene Sulfonate, Caprylic/Capric Triglyceride, 1, Sorghum Bicolor Stalk Juice, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Teprenone, Dipeptide Diaminobutyroyl, Linum Usitatissimum (Linseed) Seed Oil*, Camellia Sinensis (Green Tea) Leaf Extract*, Plantago Lanceolata Leaf Extract**, Sodium Hyaluronate (L), Taurine, Tocopherol (D-alpha), Retinyl Palmitate, Ascorbyl Palmitate (L), Simmondsia Chinensis (Jojoba) Seed Oil*, Aloe Barbadensis Leaf Juice*, Pelargonium Graveolens (Geranium) Flower Oil, Anthemis Nobilis (Chamomile) Flower Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Cocos Nucifera (Coconut) Oil*, Zea Mays (Corn) Oil, Glycine Soja (Soybean) Oil, Citric Acid, Hamamelis Virginiana (Witch Hazel) Water, Xanthan Gum, Potassium Sorbate, Butylene Glycol, Carbomer, Polysorbate 20, Benzylamide Diacetate, Caprylyl Glycol, Phenoxyethanol. *Certified Organic.
Ingredients in Skinn Wrinkle Night Balm (dry-normal): olea europaea (olive butter), butyrospermum parkii (shea butter), prunus amygdalus dulcis (sweet almond butter), glycine soja (soybean) sterols, santalum album (sandalwood) wood extract, phellodendron amurense bark extract, hordeum distichon (barley) extract, caprylic/capric triglyceride and teprenone (Renovage™), bisabolol, dioscorea villosa (wild yam) root extract, C12-15 alkyl benzoate and tribehenin and ceramide 2 and PEG-10 rapeseed sterol and palmitoyl oligopeptide (Dermaxyl™), caprylic/capric triglyceride and spilanthes acmella flower extract (Gatuline Intense™), phaseolus lunatus (green bean) extract, solanum lycopersicum (tomato) extract, lavandula spica (lavender) flower oil, superoxide dismutase, thioctic acid, linoleic acid, tetrahexyldecyl ascorbate, morinda citrifolia (noni) seed oil, tocopherol acetate (vitamin E)
Ingredients in Dermasilk: Aqua, glycerin, butylene glycol, caprylic/capric triglyceride, ethylhexyl palmitate, cetearyl alcohol, cyclopentasiloxane, dimethicone, glycol stearate, stearyl alcohol, mannitol, Butyrospermum parkii (shea butter), steareth-2, ascorbyl phosphate, tocopherol, retinol, Panicum miliaceum (millet) seed extract, hydrolyzed vegetable protein, Chlorella vulgaris extract, Avena strigosa seed extract, Phaeodactylum tricornutum extract, Waltheria indica leaf extract, Crithmum maritimum extract, ferulic acid, teprenone, adenosine triphosphate, sodium chondroitin sulfate, lecithin, cetearyl glucoside, steareth-21, guar hydroxypropyltrimonium chloride, xanthan gum, pentylene glycol, hydrogenated vegetable oil, polysorbate 20, dextrin, sodium gluconate, citric acid, sodium citrate, alcohol, phenoxyethanol, caprylyl glycol, tannic acid
Ingredients in Babor: Water (aqua), Prunus Amygdalus Dulcis (Sweet Almond) Oil, Aloe Barbadensis Leaf Juice, Caprylic/Capruc Triglyceride, Butylene Glycol, Polyglyceryl-6 Stearate, Squalane, Sorbitol, Ethylhexyl Isononanoate, Panthenol, Phenoxyethanol, Dimethicone, Cetearyl Alcohol, Fragrance (Parfum), Xanthan Gum, Ethylhexyglycerin, Carbomer, Teprenone, Potassium Sorbate, Alcohol, Triticum Vulgare (Wheat) Protein, Sodium Cetearyl Sulfate, Biosaccharide gum-1, Butylphenol methylpropional, Disodium EDTA, Hydoxylisohexyl 3-cyclohexene Carboxaldehyde, Avena Sativa (Oat), Kernel Protein, Linalool, Limonene, Pantolactone, Geranniol, Ascorbyl Palmitate, Citric Acid, ethylparaben, Ascorbic Acid, Sodium Benzoate, Butylparaben, Ethylparaben, Isobutylparaben, Propylparaben, Orange 4 (CI 15510).
Ingredients in CSI Telomer: Purified water, squalane, hyaluronic acid, caprillic/capric triglyceride, teprenone, polyacrylate 13, polyisobutene, polysorbate 20, xylitylglucoside, anhydroxylitol, xylitol, phenoxyethanol and ethylhexylglycerin.
Ingredients in Isomers Renovage for Body: Aqua/Water, Cetearyl Olivate, Sorbitan Olivate, Caprylic/Capric Triglyceride, Teprenone, Ilex Paraguariensis (Leaf) extract , Butylene Glycol, Coffea Arabica (Coffee Seed) Bean Extract, PEG-60 Almond Glycerides, Glycerin, Cetyl Hydroxyethylcellulose, Coco-Glucoside, Caprylyl Glycol, Alcohol, Glaucine, Cetyl Palmitate, Sorbitan Palmitate, Glycerin, Oryza Sativa (Rice) Extract, Caffeine, Phenoxyethanol, Tropolone.
Ingredients in Medik8 Red Alert Cleanse: Aqua, Cocamidopropyl Betaine, Sodium Cocoamphoacetate, Coco Glucoside, Decyl Glucoside, Glycerin (Veg), Caprylic/ Capric Triglyceride, Teprenone, Phytonadione, Citrus Aurantium Dulcis (Sweet Orange) Oil, Sucrose, Acacia Farnesiana Gum, Potassium Sorbate, Sodium Benzoate, Benzyl Alcohol, Quillaia Saponaria, Yucca Vera, Citric Acid, Limonene, Linalool, Citral