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Pure Skin Cellular Night Cream with EGF- reviewed and recommended

Is a Solution for:
Sagging Skin, Face Care for Men
August 12, 2010 Reviewed by Mark 5 Comments
Since night is the time our bodies heal and replenish as we sleep, it also is an opportune time for application of skin products to reap their benefits. For me the problem has always been that many products designed for night application were just too thick and heavy for my skin.  So I’ve long ago skipped the creams and usually opted for lighter serums in their place.  Granted, I still am sold on the way serums work with my skin, but the lure of a night cream with an interesting ingredient was too much for me to resist trying.

Although I’ve heard of Epidermal Growth Factor (EGF), Pure Skin Night Cream is the first product containing it that I’ve had the opportunity to try.  The Pure Skin website describes EGF as a “polypeptide growth factor which stimulates proliferation of a wide range of epidermal and epithelial cells.  This growth factor contains 53 amino acid residues which can work to remodel the skin without the irritation of retinoids or low pH acids.”  Other key active ingredients listed are SYN-COLL and hyaluronic acid. Also listed are several botanical extracts including arnica montana, elder flower, ivy, marshmallow flower, and black willow bark, known for their various soothing, anti-inflammatory, and astringent properties, to name a few.

I was pleased with the consistency as it was more like a lotion than a cream, and found it to absorb well without leaving the skin feeling greasy like some night creams can.  The immediate results I noticed was waking up to moisturized (not greasy), well hydrated skin that remained so throughout the day.  As my use progressed I have also noticed my skin tone is plumped up a bit and firmer with fine lines becoming slightly less noticeable and (although not bad to begin with), even my neck seems to have benefited and appears to have better tone. This also has a light cucumber fragrance, which I did not find objectionable.  With continued use, I have seen improvement in my skin and would recommend this product.  Additionally, a little bit goes a long way which is always a bonus – used nightly on the face and entire neck for about a month, the 1.7 oz ($65) screw top jar is still half full. (I excluded the forehead and nose, as these are my problem areas that might get clogged pores or break out.)


Thermal water, sunflower seed oil, hyaluronic acid, octyl palmitate, glycery stearate, peg-100 stearate, stearic acid, dimethicone, palmitoyl tripeptide-3, cetyl alcohol, cetearyl alcohol, ceteareth 20, propylene glycol, triethanolamine, epidermal growth factor, EDTA, imidazolidinyl urea, methylpropylparaben, vitamin E, pellitory extract, ivy extract, arnica extract, elder flower extract, marshmallow extract, black willow bark extract, fragrance.
  • May 5, 2013

    by Veno DosSantos

    EGF was discovered in the saliva of rats, it contains 53 Amino acids, which is required for cell growth and rejuvenation.
    The Cubans have been very successful in Re-arranging the DNA structure to allow cells to grow in an Organized fashion.
    In Cuba the drug Heberprot-p was developed to combat Diabetic Foot Ulcers, and the reduction of Amputations. (In Venezuela, after introduction of the drug, prevented 18000 Amputations).
    How it will be administered in Faxial cream.... Is the Big Question...
    But I have NO DOUBT, that it will be the future for Skin Growth, and cell rejuvenation.

  • August 12, 2010

    by Mark

    Valerie - I applaud you for starting early - I really do believe it pays off.

  • August 12, 2010

    by Valerie

    Thank you Junko for the link.


  • August 12, 2010

    by Junko

    Hi Valerie,
    TIA has a few articles about DMAE so here's a start and it contains links for more reading: Maybe too Marta can additionally comment with current thoughts...I'll be interested too in what she has to say about both these ingredients.

  • August 12, 2010

    by Valerie


    Like some glycolic peels might be harmful to young skins, I wanted to to know at what age is it ok to use Epidermal Growth Factor (EGF)?

    I am 25 years old with no signs of aging but beside using suncreen I wanted to start prevention (Eg.Collagen buildup with peptides, moisturizing,...).

    what exactly does Epidermal Growth Factor (EGF)do for the skin?

    Could you do a post on Epidermal Growth Factor (EGF)and DMAE? What are the pros and cons? Also at what age they might be beneficials to the skin?

    Thank you

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