Reviewed by Cindy

After reading about Retrospect products on the Truth in Aging site, I was anxious to try Retrospect C4-7 Intensive Serum ($90) on my 63-year-old skin, which has lately started to sag noticeably (hopefully only to me), and my neck has aged dramatically in the past six months. I’m hoping to stop both processes in their tracks and improve them both at the same time.

The literature from Retrospect states, “The Replicine Functional Keratin activates specialized cells in the skin so that they produce collagens 4 and 7 (C4-7) at the point in the skin where wrinkles form. Replicine causes the skin to produce the right collagen in the right place to rebuild skin structure and reverse wrinkle formation. The cell’s master antioxidant, glutathione, is uniquely boosted by application of Replicine Functional Keratin providing the skin with its own protection against oxidative stress.”

Wow. It certainly sounds like the perfect antidote to aging skin.

A .5 oz. bottle of Retrospect C4-7 Intensive Serum arrived November 7. It was nicely packaged (maybe a bit extravagantly) in a pretty red plastic cube with a pump that doesn’t dispense too much.

There was no noticeable fragrance, and the consistency was smooth and creamy...  not heavy. At the first application, I could feel my skin tighten almost immediately, not as overwhelming as a mask, but it was noticeable.

The instructions state: “After priming skin with Protein Surge Gel Cleanser, apply C4-7 Intensive Serum morning and night to face and neck to reduce fine lines and wrinkles. Follow with Day Shield or Night Renewal.”

Not having the other Retrospect products, I hoped the serum’s success didn’t rely on their interaction to work effectively.

On the morning of Day 3, I (think) I saw a slight diminishing of the lines around my eyes and mouth. It could have been my imagination, but encouraged, I kept a close eye on any suspected improvement.

At the end of the first week, I could see a noticeable difference in the lines on my face; the texture of my skin was smoother, and the tone seemed more even.

On Day 13, the pump stopped working, and after dismantling the pretty red container, I was very disappointed to see that it was empty. I was only able to extract enough for two more applications.

I don’t feel that two weeks is adequate time to evaluate or fully appreciate this product. If it does activate the skin to produce collagens 4 and 7 (C4-7), this process would take more than a couple of weeks. Based on the improved appearance of my skin, I can only assume the serum would provide long-term benefits... but based on the $90 price tag, I would be reluctant to invest that much without more dramatic results.

In terms of the ingredients, Retrospect C4-7 Intensive Serum does not contain parabens, sulfates, synthetic colors or fragrances, GMOs, phthalates, Triclosan or mineral oils.

Ingredients: Water, Oxidised Keratin, Keratin, Hydrolyzed Keratin, Ethylhexyl Olivate, Tocopherol, Butyrospermum Parkii (Shea) Butter, Calendula Officinalis Extract, Retinyl Palmitate, Cyclopentasiloxane, Dimethicone Crosspolymer, Carbomer, Phenoxyethanol, Tetrasodium EDTA, Ethylhexylglycerin, Sodium Hydroxide, Lactic Acid