I wonder why it is that most of us obsess over our faces (my husband swears that I have a different cream for every zone from eyes to upper lip to the tip of my nose) to the neglect of other parts of our anatomy that almost always just as visible: the neck and hands. I have someone else's. Someone who is older and probably farms.

I've been trying to make amends with neck stretching exercises, LED sessions and hunting down a potion that will make a visible difference. I had been getting good results with Dr Perricone's neck cream, but with Dermaxime's Rejuvenating Day Cream I may be really on to something. I have been recently getting to know Dermaxime, a South African brand that knows its ingredients (particularly peptides and antioixidant botanicals). I have become a convert to toners thanks to Dermaxime.

The Rejuvenating Day Cream ($92) is thick and creamy enough to feel as though it might penetrate a fairly tough hide. Of course, I could have used the cream that Dermaxime markets especially for the neck. In fact, though, they are very similar and, while Rejuvating Day Cream is well-liked by my neck, I think my face would find it too heavy. There are quite a few thickening agents in this cream and they may be responsible for the unctious texture.

The ingredients (as one might expect from a manufacturer that resides under a blistering African sun) are designed to fight photodamage. One of the most interesting is hexapeptide-10, which also goes under the name of serilsenine and is made a Spanish company called Lipotec. A hexapeptide is a chain of six amino acids that stimulate cell activity by interacting with specific molecules. The result is that collagen is rebuilt and fine lines are supposed to be reduced and pore size reduced.

Also made by Lipotec is tripeptide-1. This is a synthetic peptide that contains glycerine, histidine, and lysine. When it is combined with wheat and soy proteins it becomes something called aldenine and aldenine is all about collagen. When you were four years old, 90% of your collagen was collagen III. At age 50 90% of your collagen has become collagen I. Naturally, we’d all rather have collagen III and Aldenine is supposed to boost production of it by 300% in seven days. It does this by going after a particular type of free radical called ‘reactive carbonyl species’. They have been studied a lot in relation to diabetes, but only recently have come to be associated with skin deterioration. Skin collagen is a favored target of the reactive carbonyl.

Dermaxime has also added in botanical antioxidants in the form of olive extracts, tea and cranberry.

Aqua, titanium dioxide/isohexadecane/triethylhexanoin/aluminum stearate/polyhydroxystearic acid/alumina, caesalpinia spinosa oligosaccharides/caesalpinia spinosa gum/ glycerin, propylene glycol, tocopheryl acetate, cyclopentansiloxane/C30-45 alkyl cetearyl dimethicone crosspolymer, hexapeptide-10, jojoba seed oil, hydrolized wheat protein/hydrolized soy protein/xanthan gum/tripeptide-1, cetearyl olivate/sorbitan olivate, hydrogenated olive oil/ olive fruit oil/ olive oil unsaponifiables, cranberry seed oil, green tea, phenoxyethanol/ethylhexylglycerin, parfum, retinyl palmitate, viola tricolor extract, clary oil, acrylates/10-30 alkyl acrylate crosspolymer, disodium EDTA, sodium hyaluronate, thioctic acid, sodium hydroxide