Posted by Kate

In the Civil War and both World Wars, a great many injured soldiers survived their initial wound but would ultimately succumb to infection, because the simple antibiotic we know today as penicillin did not yet exist.  Once penicillin became widely available in 1943  (just in time for D-Day) and became a standard course of treatment for infection, mortality rates for wounded soldiers dropped by more than 60%. An entire class of "cillins" is now available, and these "Cillins" are prescribed by physicians and used by millions of consumers with great success, world wide.

Except by people like me. I am allergic to penicillin and the whole "cillin class".

What does my allergy to penicillin have to do with Prevage Total Transforming Anti-Aging Moisturizer? Prevage contains an ingredient that works quite well for most people without unwanted side effects, but just like penicillin, it might not be right for everyone.

The Prevage Body Treatment product works in a completely different way to the other body treatments or "moisturizers" I have tried, because it contains an ingredient used in relatively few product lines called Idebenone (ee-dee-ben-OWN). Some users of the Prevage line (especially the facial treatment) have reported mild to severe reactions ranging from hives, blisters, rash and skin eruptions, and it is likely due to idebenone. These allergic reactions typically developed immediately following the first application, but some allergies appeared months into the continued use of the product.

No such problem for me at the end of week five... only positive results!  Small scars and discolorations are less visible and the small  freckles and "sun spots" on my forearms and hands are a bit lighter in color and smaller in diameter. Those results are not mind blowing, but I haven't been using it long, so I consider it to be a positive result for such a short period of time. I am, however, noticing that my neck and jaw line are much tighter, which was quite a nice surprise.

For more than a month I have applied Prevage every morning and night to my neck, chest, forearms and hands, but I began this only after completing the required 3-day "inner arm spot" test, and having graduated from my fourteen "once per day" applications to twice per day. The package insert is very clear regarding testing for adverse reactions, so be smart and follow directions. Do not skip or rush either of these two important steps, and save your receipt in case you need to return the product due to rash.

The Prevage Body Treatment product is also marketed as an effective treatment for stretch marks and dimpled skin, but I have not used the product on either of those two conditions. What I can say, however, is that "stretched" skin is really quite similar to "wounded skin"....the body repairs itself with cells which are of a different texture, color and smoothness, so if Prevage Body Treatment works on my old scars, I would expect it to work on stretch marks too.  All in all, I would give the Prevage Body Treatment product a thumbs up!

For those of you who like to know the product "how's and whys", the key ingredient is the antioxidant Idebenone. Idebenone falls into the same classification as Kinetin, Coenzyme Q10, lipoic acid, vitamin C, and Vitamin E. The difference however, is that because the cell size of Idebenone is much smaller (60% smaller than Q10) , it pentrates differently and therefore may be potent and in some cases, more effective.  Idebenone's "Environmental Protection Factor (EPF) was tested by PHarma Cosmetix Research, LLC, and was rated highly in a small scale consumer test  for 1) Sunburn Cell Assay, 2) Photochemillluminescence, Primary Oxidative (Protection), Secondary Oxidative (Protection), UVB Irradiated Keratinocytes (Protection). The test was created to determine how well an antioxidant will protect the skin from premature cell death, changes in cell membranes, cytoplasm, mitochondria, and damage to DNA.

The Prevage line is available in an OTC (over the counter) formula containing .5 % Idebenone, and the original prescription version of Prevage (available through Dermatologists) called PrevageMD, contains 1% Idebenone. There is debate regarding any difference in effectiveness (or incidence of rash) between the two strengths. Consult your Dermatologist if you want an expert opinion.

Prevage Body Treatment is also a fantastic moisturizer. I am not wild about the seemingly ever present parabens, but I must admit Prevage feels wonderful going on, likely due to the addition of Shea Butter, Glycerin, and "other" emollients. It smells delightfully fresh and creamy, with a hint of oranges, and while expensive ($135 for a 6.8 oz tube), at the rate I am going, this tube will likely last me for at least 2 months... so just over $2 per day for 2x treatments.

If you have tried the product and have new information to add, please do reply to this post and let us all know how it worked for you.

Other Ingredients:

Purified water (aqua), glycerin, cetyl ricinoleate, isohexadecane, ceresin, glyceryl stearate, water. titanium dioxide (C177891), propylene glycol, styrene acrylates copolymer, hydrolyzed corn starch, ammonium hydroxide, phenoxyethanol, methylparaben, ethyl-paraben, butylparaben, propylparaben, isopropyl lauroyl sarcosinate, sericin, hydroxydecyl ubiquinone (idebenone), sodium PCA, steareth-2, PEG-60 hydrogenated castor oil, PEG-100 stearate, glycosaminoglycans, linoleic acid, linolenic acid, tocopherol, millet (panicum miliaceum) extract, cholesterol, ceramide III, dimethicone, PEG-50 dipolyhydroxystearate, magnesium aluminum silicate, xanthan gum, cetyl hydroxy-ethylcellulose, disodium EDTA, BHT, diazolidinyl urea, methylparaben, propylparaben.