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Reviewed and recommended: ReLuma Skin Illuminating Anti-Aging Serum

Reviewed by Marta September 15, 2008 42 Comments


Growth factors have a positive impact on lines and skin tone


The airless pump can be eratic
One of the best anti-aging serums we've come across

I'll get straight to the point: ReLuma Skin Illuminating Anti-aging Serum ($145/0.5oz in the shop) works. In fact, I would go so far as to say this is one of the best anti-aging potions that I have come across. It is about a month since I bought and started to try out ReLuma and it has had a significant impact on overall skin tone, plumpness and diminished wrinkles. And - an important plus for me - no allergic reactions or even the slightest sensitivity.

As we age, the critical proteins for healthy skin start to decline. These proteins and growth factors can be isolated as PDGF, VEGF, FGF, IGF3 and TGF-B. Of these, TGF-B is thought to be the most important because its signals are recognized by the majority of cells. TGF-B expression is also induced during wound healing and studies show that it can increase collagen and fibronectin. Meanwhile, PDGF "increases the rate of cellularity and granulation in tissue formation through increased fibroblast function".

Although PDGF, VEGF, FGF, IGF3 and TGF-B all do their own thing, it is the combination of them that is supposed to get results. For example, in order for TGF-b to stimulate fibroblast cell growth, the presence of PDGF is required. In all, ReLuma has nine different human cytokines in the human fibroblast conditioned media.

So where do they come from? The progenitor cells of the human fibroblast are taken from newborn baby foreskins. These are doubtless from babies whose parents volunteered to have them circumcised and no harm was done (I can't help thinking that there is a nice little sideline for rabbis here). Conditioned media is, in fact, the solution (sugars, amino acids and such) that is put in the petri dish in which the cells are grown. The cells secrete stuff or release it when they die and these proteins are then gathered up and put to use ReLuma.

Back to ReLuma. A couple of tiny caveats: the airless pump is a bit erratic (but then that is all too common) and the serum feels a bit tacky for about 10-15 minutes after application (this seems to wear off and this is not in the slightest one of those shiny/greasy numbers). The two preservatives are potential allergans (the iodopropynyl butylcarbamate was accused of such in a Danish study) and DMDM hydantoin can irritate those of sensitive skin. That would be me, but I am happy to report that I have had absolutely no adverse reactions to ReLuma.

I was so pleased with ReLuma's results for me that I contacted Invitra over the weekend to see if I could spread the love. They responded promptly and generously and I'll shortly be receiving a handful of samples for readers to (honestly) review. Please leave a comment to persuade us that you are deserving and honest.

ReLuma was reviewed again in 2011.

Ingredients in ReLuma Skin Illuminating Anti-Aging Serum

Human Fibroblast Conditioned Media, deionized water, gycerin, sodium PCA, allantoin, panthenol, cellulose gum, DMDM hydantoin, iodopropynyl butylcarbamate.

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  • February 8, 2012

    by dawn

    Used this for years husband a doc. Amazing results. Especially in conjunction with my regular skin care regime. I take skin care VERY seriously. like my hubby says"Nothing is as good as natural." Therefore he strongly stresses to his patients, and myself that maintenance is everything. No exaggeration my skin looks as good as it did if not better than when I was a teen. Only downside..EXPENSIVE. (Even though we hardly mark it up). Therefore we only sell it to skin care fanatics like myself who take allot of pride in their appearance. FYI, although expensive it is not nearly as expensive as a face-lift, or worse, a botched face-lift. I just noticed that free samples are available online at various sites. Try it. You won't be disappointed, or respond to my post and I will happily send u pics of me at 17 and me now. Without revealing my age i will tell u i have a son who is currently matriculating an Ivy League University. Oh one more thing. I am in no way affiliated with the company that manufactures it. I wish I was so I could get a major discount. LOL. Take good care of yourself, and treat yourself gently. Dawn

  • June 27, 2011

    by NoeyD77

    Although I am really against skin care products that cost that much since I truly believe there is no justifiable reason for such exorbitant cost, I am DYING to try any of Reluma's products. I RARELY, if ever listen to the recs of aestheticians since my experience with them has been that they are motivated by sales of lines they carry, HOWEVER Marta ALWAYS backs her claims up with such serious SERIOUS science, I'm actually beginning to think she may be a lab-coat wearing biochemist who has discovered the fountain of you and refuses to share LOL LOL that I am now really wanting to give either Reluma or YBF a shot, but sadly its just simply out of my budget :)

  • June 27, 2011

    by Marta

    Hi Stephi, GFs are not peptides. They are not the same thing at all. You can read more about peptides and growth factors in these posts:
    Despite your protestations of not being motivated by hate, I couldn't help but notice that you are writing from the same IP address that has been actively posting online against ReLuma. What is your agenda exactly?

  • June 27, 2011

    by Stephi

    Everyone know GFs (peptides) are sensitive to light, that is why TNS, neocutis, revive and AQ skin solutions (all GF products) don't have clear bottles because of this fact. On the other hand Reluma uses the same clear containers for all of its products. Doesn't that strikes you as weird. I know you are promoting this product because you are making money, but there are better products out there made by honest people with legitimate science. this post won't last here.. stay away from Reluma and invitrx..I say this with sincerity and not hate.

  • February 24, 2011

    by Julie Kay

    No, no, no. I wasn't chosen! HAHA! Not for Reluma (here). But revisiting this thread brought back memories. And what I use all has its basis in my knowledge base learned here at TIA. I think my 7th decade is going to be brilliant. ~jk

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