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Reviewed and Recommended: Skin2Skin Care Anti-Wrinkle Night Recovery

Is a Solution for:
Sagging Skin
January 27, 2009 Reviewed by admin 8 Comments
Finding a skin care line that combines a relatively clean slate of organic ingredients with an effective set of clinically-proven anti-aging components can be a daunting challenge. I accepted this challenge head-on and emerged victorious with my discovery of Skin2Skin Care, a line of 100% natural, non-toxic products formulated for mature skin. After testing the Anti-Wrinkle Night Recovery for a full month, I am very content with the condition of my skin, even in the dead of a New York winter (a feat in itself).

I can not only feel but smell the freshness of this cream, which reminds me of a soft pretzel. My skin relishes its rich texture at night, and when I resurface the next morning, it appears well-hydrated, soft, and smooth. The Anti-Wrinkle Night Recovery boasts three key active ingredients: dermaxyl (palmitoyl oligopeptide), eukarion 134 (superoxide dismutase), and nordihydroguaiaretic acid.

Dermaxyl is a patent-pending synthetic complex derived from advanced peptide technology. Clinically proven to reduce the appearance of wrinkles over time, dermaxyl works by encouraging healthy cell renewal and repairing age-related skin damage. Topical application of dermaxyl has been shown to boost ceramide activity, thus rehydrating and strengthening the skin. Its recommended use level is 2%, the exact concentration in Skin2Skin Care's Anti-Wrinkle Night Cream.

Eukarion 134 is an antioxidant complex that helps to prevent photodamage and protect cells against tissue injury caused by oxygen ions, free radicals, and peroxides. According to a 2004 in vitro trial, Eukarion 134 shields primary human keratinocytes against oxidative stress and increases cell survival after UVB radiation. Unlike most antioxidants, which gradually lose their protective power after attacking and disabling a single free-radical molecule, eukarion 134 has the special ability to recycle itself after each free-radical encounter, thus continuing to combat damage that leads to aging for a longer period of time.

Nordihydroguaiaretic acid is a bioactive component of the long-lived Mexican desert plant, Larrea Divaricata, (aka creosote bush or chaparral) widely used by Native Americans as a sunscreen and as a treatment for blood poisoning and hepatic diseases. Recent studies of nordihydroguaiaretic acid have revealed biological properties as a free-radical scavenger and a protective agent against keratosis caused by exposure to UV rays. A potent antioxidant, nordihydroguaiaretic acid has demonstrated significant anti-inflammatory and anti-cancer properties for skin. A 2006 study found that this compound suppresses growth in breast cancer cells by inhibiting the function of key receptors.

Each of these unique anti-aging ingredients is supplemented by vitamins A, C, and E, as well as a staggering inventory of organic extracts. And not a paraben in sight. The cream's clear basis in natural ingredients and high concentration of effective anti-aging elements extends to other products in Skin2Skin Care's line as well. Skin2Skin Care has generously offered Truth in Aging readers a coupon code (Firstbuy) to receive 20% off their first purchase.

Even better, newsletter readers will have an exclusive chance to win three full-sized samples of Skin2Skin Care's Anti-Wrinkle Night Recovery ($92) this Wednesday.


Purified Water, Glycerine (Vegetable Oil), Palmitoyl Oligopeptide, Superoxide Dismutase, Caprylic/Capric Triglycerides (Coconut Oil), Cetyl Alcohol (Coconut Oil), Sesamum Indicum (Sesame) Seed Oil, Shea Butter (Butyrospermum Parkii) Fruit, Cetyl Palmitate (Palm Oil), Ceteareth-20 (Palm Oil), Cyclopentasiloxane (Silicone), Dimethicone and Dimethiconol (Silicone), Sodium Carbomer, Disodium EDTA, Nordihydroguaiaretic Acid, Retinyl Palmitate (Vitamin A), Ascorbyl Palmitate (Vitamin C), Tocopheryl Acetate (Vitamin E) ), Steareth-21 (Palm Oil), Ethylene Glycol Monostearate (Coconut Oil), Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid (Grain).

Certified Organic Extracts of:

Punica Granatum (Pomegranate), Rubus Fruticosus (Blackberry/Loganberry) Leaf, Daucus Carota Sativa (Carrot) Root, Camellia Sinensis (White Tea), Camellia Oleifera Leaf (Green Tea), Symphytum Officinale (Comfrey) Leaf, Lonicera Caprifolium (Honeysuckle) Flower, Zingiber Officinale (Ginger) Root, Equisetum Arvense (Horsetail), Rosa Canina (Rose Hips) Seed, Malva Sylvestris (Mallow), Borago Officinalis (Borage) Seed Oil, Sambucus nigra (Elderflower), Aloe Barbadensis (Aloe Vera) Leaf Juice, Trifolium pratense (Red Clover), Althaea Offinalis (Marshmallow) Root, Chamomilla Recutita (Matricaria) , Macrocystis Pyrifera (Sea Kelp), Panax (Ginseng) Root, Ilex paraguariensis (Yerba Mate), Fucus Vesiculosus (Bladderwrack), Malva silvestris (Blue Malva Mallow), Porphyra Yezoensis (Nori), Ginkgo ( Ginkgo Biloba ), Humulus Lupulus (Hops), Citrus Grandis

  • September 9, 2015

    by Marta

    That's a good question Kimberly. We don't often do updates. But you are making me think that we should - somehow. I've raised your comment with Elisa, our editor and community manager, and we'll have a think about the best way to go about it. Perhaps we'll just ask reviewers to hop on and leave a comment after 6 months and tell us if anything changed and/or they ever bought the product. Any suggestions gratefully received.

  • September 8, 2015

    by Kimberly

    If the product review page has no new link notes for updated reviews, can we assume that the reviewed product hasn't been updated by original poster for continued efficacy or noting whether it remains a part of their skin care regimen or even if the formula perhaps hasn't been updated? I realize reveiwers test a lot of products so it's understandable if it's not still used. Nevertheless was curious as to whether previous reviewed products are ever revisited especially if or when formulas are enhanced. Thank you.

  • June 20, 2012

    by Susanna Schreiner


    I loved your review on the night creme and was wondering if you are still using the Skin 2Skin Anti-wrinkle Night Recovery? Do you continue to like it and see the benefits? I have been having problems finding a night creme that is chemical free and organic with the anti-aging benefits. Many contain C13-14 Isoparrafin, which I like to stay away from as well. I really need the anti-aging benefits now that I am 43. Have you found something better or do you still prefer this one?

    Thank you!

  • January 28, 2009

    by copley

    Hi Kira-
    Eukarion-134 catalytically mimics the activity of superoxide dismutase (which is #4 on the ingredients list), an enzyme used by the body to protect tissue against toxic compounds (known as reactive oxygen species).

  • January 27, 2009

    by Julie Kay

    This potion looks yummy! ~jk

  • January 27, 2009

    by Kira

    Niall - sorry I accidentally misprinted your name:-)

  • January 27, 2009

    by Kira

    Thnx for your review! Can't seem to find Eukarion 134 in ingredient list, can you help?

    This forum you mention is where I read about Eukarion 134, but could't try it bcs I refuse to use anything from the Clinique brand. Great to see that there is a better formulation out there!

  • January 27, 2009

    by Niall

    I was really intrigued by the (to me) new antioxidant Eukarion 134. I found a nice info page on how it works, with links other info. Sounds like a very interesting substance indeed.

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