Avon claims that 82% of women who tried Avon Anew Clinical Derma-Full 3X in a trial, and responded, said they thought their cheeks looked more full and youthful. I shall not be joining them. I have been testing this curious-looking potion for a scant four weeks and, although I try to give a final verdict after at least a month, I can't really bring myself to keep on using it. Before, I tell you a bit more about my experience with Clinical Derma-Full 3X, I should mention that we offered a second bottle to a reader to test and her feedback, when we get it, may well be more positive (you can go to our reader review here).

In the meantime, I had a relatively violent reaction to Derma-Full within two days of using it. A rash of large zits appeared where I had applied it (the right chin, nasolabial area). Now, as my esthetician would say, it is not really fair to judge something by whether I react to it since sensitive skin is my middle name. Other people may take to this product just fine. However, in my case, I was forced to stop using it for a few days until everything subsided. Since then, my reaction has been less spectacular: redness and a bit lumpy under the skin (thankfully, no eruptions). It does sting though for a good half hour after application.

My primary quibble is that it hasn't worked for me at all. What is supposed to happen is that skin plumps up and I was hoping to see an improvement to my nasolabial area (which is only just beginning to haunt me, so its not as if the product faces a Herculean task). And Clinical Derma-Full X3 had some promise: Avon claims it has the same HA facial filler as that injected by dermatologists, although it is listed in the ingredients as plain old sodium hyaluronate. As well as HA, Avon has added in Matrixyl, a powerful antioxidant peptide. Still, sodium hyaluronate is a very standard cosmetic ingredient and, in my case, the results were pretty standard too. 

Thiodipropionic acid is an antioxidant, although it is primarily used for preserving food and I couldn’t find any evidence of its role in skin care. I did, however, find some references to tests conducted on rabbits that demonstrated skin irritation, so this may have been the ingredient that caused my reaction.

The reason why I used Avon Derma-Full on one side of my cheek only is because I wanted to try out Nutra-Lift Rejuventating Therapy. It also has Matrixyl, but in the form of its more powerful sibling Matrixyl 3000, as well as copper peptide and liposomes. Nutra-Lift, by contrast, has succeeded in slightly filling in the fine lines on my chin and of the nasolabial. So, I'll be sticking with Nutra-Lift for the time being.

Ingredients in Avon Derma-Full 3X

Water, glycerin, cyclopentasiloxane, propylene glycol, glycolic acid, thiodipropionic acid, trioxaundecanedioic acid, ethylhexyl salicylate, sodium hyaluronate, phytol, fennel extract, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, PEG/PPG-18/18 dimethicone, dimethicone crosspolymer, butylene glycol, carbomer, ammonium hydroxide, caprylyl glycol, polysorbate 20, fragrance, phenoxyethanol, disodium EDTA, Mica/CI 77019, titanium dioxide/CI 77891, blue 1/CI 42090, Red 4/CI 14700.