Update June 2010: we are no longer recommending this or selling it as we found it is the exact same formula as a cheaper version by CSI (click for more on this and other product twins).

I have been testing and very much like Revive DNA Rejuvenation Cream. It is an anti-ager that packs a high moisturizing punch and I have used it to good effect on crow's feet and as a quencher for the thirsty skin on my neck. The star of Revive's show is teprenone, arguably the new 'it' ingredient especially since it became associated to Nobel Prize winning research on telomeres.

First, a quick telomeres 101. If DNA is broken there are two options after the cell cycle is stopped: repair or death. If cells divided without telomeres, they would lose the end of their chromosomes, and the necessary information it contains. They are often described as being like the tips on the ends of shoelaces that stop them unraveling. Telomeres shorten every time a cell divides. When they become very short, they trigger cell crisis and cell death. As we know, cells can only replicate a limited number of times – a phenomena called the Hayflick Limit. There’s more on telomeres in an article posted last August.

Teprenone, also marketed as Renovage, promises to stabilize telomeres so that they won’t shorten any further than they already have. In addition to Revive, you'll find teprenone/Renovage in Your Best Face's Boost and Osmotics Renovage eye cream.

The refreshingly short ingredients list in Revive includes xylitylglucoside anhydroxylitol xylitol, which might sound like a song from Mary Poppins but is in fact a sugar found in wheat and olives that helps skin retain moisture and boosts the skin’s natural hyaluronic acid. It improves the barrier function of the skin, increasing ceramide synthesis. This ingredient isn't all that common, but you will find it in Hydrapeptide's Lash growth product. Revive also has a Middle Eastern plant called astragalus. Topically, it can also be used to treat wounds and burns. According to the University of Maryland, it is an antioxidant and anti-inflammatory.

It must be noted that there are a few fillers; polyacrylate is a film former, polyisobutene is a thermoplastic, and polysorbate 20 is an emulsifier that can cause skin irritation. Whilst eshewing parabens, Revive uses the preservative phenoxyethanol, a known allergan.

Revive is made by PureRadiance, a newish company that also makes Infuse, a hair thickener. Behind PureRadiance is Dr Al Sears, an odd character to say the least and I must admit that I can't work him out. He appears all over the internet with hair that varies from buzz cut to lion's mane apparently decrying sensible things such as exercise and sunscreen. Underneath the image of a tacky pedlar of supplements such as CQ10 (the PureRadiance website thankfully seems to be in the hands of entirely different marketing team), Dr Sears is rather intriguing. He actually does promote exercise, its just that it looks a lot like interval training and I don't disagree with him that chemical sunscreens are potentially harmful. On the other hand, he is selling a pill that is supposed to give you sun protection. Anyway, I shall look into Dr Sears...More to come.

Ingredients in Revive

Purified Water, Squalane, Hyaluronic Acid, Caprylic/Capric Triglyceride (natural thickening agent derived from coconut), Teprenone, Polyacrylate 13, Polyisobutene, Polysorbate 20, Xylitylglucoside, Anhydroxylitol, Xylitol, Astragalus, Phenoxyethanol, Ethylhexylglycerin.