Reviewed by Dennis on August 28, 2013


It is easy for me to know when I really like a new product while testing it. First, I start to worry about running out and I will start rationing it. Second I start trying to convince myself that it's worth it to actually purchase, no matter the price. Sadly I have had neither of those feelings with the Senté Dermal Repair Cream ($169.95) I am testing.

Senté is a "science based" beauty line. Their flagship product is their Dermal Repair Cream and their signature ingredient is Glycoproteins. I was happy to see the short list of ingredients on their website when I was first asked to test the Dermal Repair Cream. I had never heard of glycoproteins in skin care so I was very interested. Glycoproteins are proteins that contain a carbohydrate attached to a protein. I have come upon many claims of its legitimacy when they come to skin care:  cellular repair, increased energy level of skin cells by enhancing the production of energy-rich adenosine and increased hydration and elasticity.

Senté claims this ingredient to be a "breakthrough" further saying their glycoproteins "are 'biologically active,' attaching to the surface of cells and allowing growth factors and other molecules to regenerate the skin."

I have been using Senté Dermal Repair Cream for over a month, and though I think it is an okay moisturizer I have not experienced any ground breaking results nor any of the claims listed on their website such as "profound hydration." I understand the need to talk up your product, but come on.

When my package of Senté Dermal Repair Cream arrived the first thing I noticed was that the ingredients on the box did not match those on the website and that really turned me off. However, to be fair the website only lists key ingredients, the top being glycoproteins.

Glycoproteins is not actually spelled out on the box. I wrote Senté asking for clarification and they were kind enough to get right back to me, "Heparan Sulfate (HS), the active ingredient in Senté Dermal Repair Cream, is a Glycoprotein. Many people are not familiar with HS but are familiar with Glycoproteins, so we use that name as an umbrella term. Other examples of Glycoproteins are Hyaluronic acid, Dermatan Sulfate & Chrondroitan Sulfate, all which are not present in our product."

Strange since hyaluronic acid is listed as an ingredient on both the site and the product, but this might just be a matter of confusion.

The cream itself is white and fragrance free, but there is a scent which is very pleasant and dissipates before you even finish rubbing it in. I found the cream does not have a lot of slip and I thought it dried out too quickly, before I could spread it completely over my face. I had to use about five pumps to cover my face and neck. It does leave a nice finish. No greasy feeling or shiny appearance. There is retinyl palmitate so it's recommended to only use at night.

The dispenser itself is very well designed and I had no problems using it.

Perhaps Senté's Dermal Repair Cream needs more time to come into its own. And although I was happy to test and think that Heparan Sulfate is an interesting ingredient and the rest of the ingredients here are fine with no real nasties, the same can be said for a lot of moisturizers at a much lower price point. I do not see myself mourning or repurchasing the Senté it once it's finished, unless after writing this, I see some profound, groundbreaking results.