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I have been a Skin Nutrition fan for a number of years and think highly of the Skin Nutrition Cell CPR Facial Serum and the Skin Nutrition Night Cream. Unfortunately, my skin did not feel similarly nourished by the reformulated Skin Nutrition Cell CPR Eye Reconditioning Serum ($100).
The first issue that I had when testing reformulated Cell CPR Eye Reconditioning Serum is that the cream was extremely runny when squirted out from the bottle. So much so that I found it impossible to apply to my eyelids or under-eye without some of the cream dribbling into my eyes themselves. The result was mild to moderate stinging that lasted about 10 minutes. This was resolved to some extent after a quick discussion with Truth In Aging customer service — the ever creative and practical Preksha suggested giving the bottle a firm shake before use.
The shaken cream pumped out in a thicker and much more usable consistency. Unfortunately, even careful application triggered a mild irritation. It was mild enough to put up with, but my test results were inconclusive. While my eye wrinkles did not really get worse, there was certainly no improvement.
In terms of efficacy, I cannot compare it to the original formula, but you can read the review by Truth In Aging community member, Cristina, from 2012. A glance at the ingredients suggests that almost every one of them has been changed. Some for the better — but not all.
The first major active is acetyl tetrapeptide-5, which goes by the name of Eyeseryl. This peptide supposedly has anti-edema properties that are helpful for reducing puffy eye-bags. As this isn’t a major concern of mine, I would probably have preferred the collagen-building Matrixyl 3000 that was in the original formula and absent from the new one. I do, however, like the addition of caprooyl-tetrapeptide-3, a peptide that is marketed as ChroNOline and is supposed to reduce sagging. Plus there is a growth factor, sH-Oligopeptide-1, the “synthetic human” stem cell that is in Medik8 Growth Factor Youth Activating Serum ($160) and Osmotics Blue Copper 5 Prime ($135). Clinical trials by the manufacturer show results on wrinkles after 12 weeks.
While Skin Nutrition Cell CPR Eye Reconditioning Serum wasn’t really for me, if you have puffy — and non-sensitive — eyes, then it could be worth a try.