Free shipping on all domestic orders over $39

Skin Nutrition Cell CPR- reviewed and recommended

November 10, 2009 Reviewed by Marta 14 Comments

Skin Nutrition, the maker of Cell CPR ($170) says “if our skin came with a manufacturer’s maintenance elixir, Cell-CPR™ is what it would have come with!” After four and half weeks of testing, I'd have to say that my skin agrees with this bold claim. I have been using it  over Cellbone's Hyper Peptide and although I am conscious that this powerful peptide combo could be overkill, my skin has never looked better: plump, glowing and a little less wrinkled.

Skin Nutrition's philosophy is that skin cells are complex things made up of phospholipids, proteins (enzymes, oligopeptides, amino acids), oligosaccharides, oxygen, vitamins and minerals. And so, therefore, is Cell CPR with a whopping 70 or so ingredients.

As I mentioned in earlier post on Cell CPR, Skin Nutrition has introduced me to some new peptides. Hexanoyl dipeptide-3 (which is lecithin and norleucine Acetate) activates skin cell regeneration by stimulating the natural desquamation process of the skin, leading to a gentle peeling. Rh-oligopeptide-1 (Egf) is a recombitant human epidermal growth factor. I have seen it in hair growth products and, apparently, it also repairs wrinkles and wounds. More familiar to me is another wound healer, copper tripeptide (also known as copper GHK).

Since I gave a call out to vitex agnus castus extract in that first post, along with uva ursi, I'll focus here on another couple of worthy botanicals. Mitraxarpus scaber is a low growing weed that was recently discovered to have a compound that is a form of hydroquinone and, therefore, its role here is to act as skin whitener. Phaeodactylum tricornutum is a type of alga that is anti-inflammatory.

One of the most fascinating ingredients is adenosine triphosphate (ATP), an ingredient that is also in DermaSilk. It is the main energy source for the majority of cellular – and muscular – functions. This includes the synthesis of DNA. Living things use ATP like a battery – storing and using energy when needed and, it seems, in complex ways (a sprinter will use ATP very differently from a marathon runner). The ATP molecule is composed of three components.  At the center is a sugar molecule, ribose (the same sugar that forms the basis of DNA).  There is a base (a group consisting of linked rings of carbon and nitrogen atoms); in this case the base is adenine. The third is a string of phosphate groups. These phosphates are the key to the activity of ATP. Research on the effects on skin is new, but very promising.

I was given a bottle of Cell CPR for this review, so the real litmus test is whether I would buy a replacement for $170. The answer is yes. It is a comfortable, lightweight cream that, quite simply, works. It is worth adding that Niall wrote in to say that he is a big fan of Skin Nutrition's much cheaper Environmental Protection Serum.


Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cyclopentasiloxane, Lecithin, Hydrogenated Lecithin, Vitex Agnus Castus Extract, Stearic Acid, Cetyl Alcohol, Phytosphingosine, Malus Domestica Fruit Cell Culture, Ascorbyl Tetraisopalmitate, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Steareth-21, Panthenol, Retinyl Palmitate, Cyclodextrin, Hexanoyl Dipeptide-3, Norleucine Acetate, Centella Asiatica Extract, Lycium Barbarum Fruit Extract, Rh-oligopeptide-1 (Egf), Rh-polypeptide-1 (Bfgf), Copper Tripeptide-1, Dimethicone/Vinyl Dimethicone Crosspolymer, Peg-12 Dimethicone Crosspolymer, Sodium Polyacrylate, Carbomer, Xanthan Gum, Isohexadecane, Polysorbate 60, Butylene Glycol, Arctostaphylos Uva Ursi Leaf Extract, Mitracarpus Scaber Extract, Superoxide Dismutase (Sod), Saccharomyces Ferment Lysate Filtrate, Sodium Hyaluronate, Hydrolyzed Vegetable Protein, Adenosine Triphosphate (Atp), Yeast Polysaccharides, Acetyl Tyrosine, Proline, Oleyl Alcohol, Dioscorea Villosa (Wild Yam) Root Extract, Glycine Soja (Soybean) Sterols, Perfluorodecalin, Ceramide 3, Rhodochrosite Extract, Hematite Extract, Phaeodactylum Tricornutum Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Sodium Pca, Trehalose, Allantoin, Peg-32, Hydroxyethylcellulose, Olea Europaea (Olive) Fruit Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Steareth-2, Peg-30 Dipolyhydroxystearate, Alcohol,Disodium Edta, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol.

  • November 25, 2014

    by Lois

    My comment is, wow what a job, or pleasure you have. I am really thrilled to read
    your comments and views on items. How did you arrive in this position? Do they need the comments of a 67 year old women, who is trying to look at least 55. I would dearly love to try some of these products without paying full price until I see if they work. You would think it would be in the companies best interest to have reliable women of all ages to try their products. If you know of anything it sure would be nice to be considered. But then, I guess you hear that all the time. I really enjoyed your comments. Thanks

  • December 12, 2011

    by Marta

    Hi Clara, here's some skincare ideas for 30-somethings

  • December 11, 2011

    by Clara Elena

    i found this website and your reviews very informative, i am pretty sure many costumers appreciate the fact that we can learn deeper about the ingredients and the function of them.
    i am in the mid 30s would you please recommend me a face product that preserves and also enhance the youth of my skin, and that boost radiance and work as anti-wrinkle as well. thanks

  • June 4, 2011

    by RichardC

    Thank you all for your honest and sincere replies. I have repurchased boost and still have a half jar of prep lying around. As for the peels and IPL, I went to the dermatologist awhile ago but found that their treatments were rather harsh and I worry about the Hayflick limit but will check out the IPL. Thanks guys!

  • May 31, 2011

    by Mark

    RichardC - a visit to a dermatologist may yield options for your issues with pigmentation and light wrinkles on your forehead such as a light peel or IPL (Intense Pulsed Light)treatment. Prices can vary widely by area, but some are very affordable. You could then maintain the results you achieve with these great products.

  • May 30, 2011

    by Marta

    I think used with Prep, you might find that Boost is enough. But if you are starting to see fine lines, then Control could be used to target them. I think I am violently agreeing with Darrell :)

  • May 30, 2011

    by RichardC

    Thank you very much for the feedback. I have very notable pigmentation on the forehead due to over exposure from the sun in the past. The top of my eyelids are a bit loose/ baggy as well. Furthermore, I couldn't use laa vie celeste's day cream as it was too oily. And because of the sun and acne, my forehead is definitely much more aged with light wrinkles all over now. I've been using the cosmetic skin solutions vit. C and correct there, on the eye area and the smile lines but nothing outside the eye area seems to have improved. Once again, I really appreciate the feedback. I loved boost as it didn't break me out but felt I needed something heavier hitting.

  • May 29, 2011

    by Darrell

    Hi there -- I just happened to take a peek at this post and glad I did (my ears were burning)...

    Control is also very preventative, but as Marta hinted you might enjoy a wider variety of benefits for your age and skin type through some other types of products.

    For sun damage and combination skin in the 20's, I would suggest Prep and Boost. Prep really helps set the stage to help prevent and turn around damage (you'll find peptides and antioxidants as are included in Control and brighteners as are found in Restore).

    You could by all means pair Prep and Restore together, but especially in your 20's and with combination skin, I think you'd experience broader benefits with a Prep/Boost combo.

    I hope this helps! I wouldn't "toss out" your Control; as you could still use it in targeted areas such as the furrow of the brow, crows feet and corners of the mouth.

    Thanks much!

  • May 29, 2011

    by Marta

    Hi Richard, as a rule I wouldn't recommend either for a 20 year old. They both contain ingredients that act like wound repairers. If you haven't got anything to repair - eg wrinkles - then you could be disappointed. Can you be a bit more specific about what you mean about sun damage? Perhaps some exfoliation would help - Your Best Face Prep or La Vie Celeste's glycolic gel mask with a good antioxidant moisturizer. Or YBF's Restore, which has skin brightening ingredients. Actually, perhaps Darrell from YBF should weigh in here.

  • May 29, 2011

    by RichardC

    Hi Marta, having used both Cell CPR and ybf Control, which would you recommend for a sun damaged, combination 20's year old? Their price points are so similar but their ingredient profiles aren't.

  • May 14, 2010

    by marta

    Megan, I asked Skin Nutrition about this and they wrote back: "the percentage of Bergamot oil in the Cell-CPR is very small, so it definitely will not have an effect in causing sun sensitivity".

  • May 14, 2010

    by marta

    Hi Megan
    You are right the bergamot (and several other essential oils) can increase photosensivity. However, it appears after about 60 other ingredients, so I imagine the amount is miniscule. I will contact Skin Nutrition though for clarification.

  • May 13, 2010

    by Megan

    This product contains bergamot oil. I am worried about the use of bergamot in skincare, it increases photosensitivity.

  • November 10, 2009

    by Olivier

    Cellbone is really an amazing company. I am obsessed with all their products.
    SkinNutrition also makes a cream for the lip. It's very light and fluid but it's amazing. I put it under a heavier lip balm and it does wonders.
    SkinNutrition also has a body mask which smell amazing(essential oil). I use it before every photoshoot.

Join the discussion! Leave a comment below.

My Comment

Add a comment...

-or- Cancel Comment
* Required Fields
truth in aging's five best

Truth In Aging's Five Best

The very best to choose from for your skin concerns.

Read More

truth in aging videos

Truth In Aging Videos

Helpful how-tos and reviews from Marta and friends.

Watch Now

meet our contributors

Meet Our Contributors

The TIA community consists of our trusted reviewers.

Meet Them

be inspired

Be Inspired

Inspiring thoughts and women who are aging gracefully.

Read More