Skin Nutrition, the maker of Cell CPR ($170) says “if our skin came with a manufacturer’s maintenance elixir, Cell-CPR™ is what it would have come with!” After four and half weeks of testing, I'd have to say that my skin agrees with this bold claim. I have been using it  over Cellbone's Hyper Peptide and although I am conscious that this powerful peptide combo could be overkill, my skin has never looked better: plump, glowing and a little less wrinkled.

Skin Nutrition's philosophy is that skin cells are complex things made up of phospholipids, proteins (enzymes, oligopeptides, amino acids), oligosaccharides, oxygen, vitamins and minerals. And so, therefore, is Cell CPR with a whopping 70 or so ingredients.

As I mentioned in earlier post on Cell CPR, Skin Nutrition has introduced me to some new peptides. Hexanoyl dipeptide-3 (which is lecithin and norleucine Acetate) activates skin cell regeneration by stimulating the natural desquamation process of the skin, leading to a gentle peeling. Rh-oligopeptide-1 (Egf) is a recombitant human epidermal growth factor. I have seen it in hair growth products and, apparently, it also repairs wrinkles and wounds. More familiar to me is another wound healer, copper tripeptide (also known as copper GHK).

Since I gave a call out to vitex agnus castus extract in that first post, along with uva ursi, I'll focus here on another couple of worthy botanicals. Mitraxarpus scaber is a low growing weed that was recently discovered to have a compound that is a form of hydroquinone and, therefore, its role here is to act as skin whitener. Phaeodactylum tricornutum is a type of alga that is anti-inflammatory.

One of the most fascinating ingredients is adenosine triphosphate (ATP), an ingredient that is also in DermaSilk. It is the main energy source for the majority of cellular – and muscular – functions. This includes the synthesis of DNA. Living things use ATP like a battery – storing and using energy when needed and, it seems, in complex ways (a sprinter will use ATP very differently from a marathon runner). The ATP molecule is composed of three components.  At the center is a sugar molecule, ribose (the same sugar that forms the basis of DNA).  There is a base (a group consisting of linked rings of carbon and nitrogen atoms); in this case the base is adenine. The third is a string of phosphate groups. These phosphates are the key to the activity of ATP. Research on the effects on skin is new, but very promising.

I was given a bottle of Cell CPR for this review, so the real litmus test is whether I would buy a replacement for $170. The answer is yes. It is a comfortable, lightweight cream that, quite simply, works. It is worth adding that Niall wrote in to say that he is a big fan of Skin Nutrition's much cheaper Environmental Protection Serum.

Ingredients

Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Dipropylene Glycol, Cyclopentasiloxane, Lecithin, Hydrogenated Lecithin, Vitex Agnus Castus Extract, Stearic Acid, Cetyl Alcohol, Phytosphingosine, Malus Domestica Fruit Cell Culture, Ascorbyl Tetraisopalmitate, Tetrahexyldecyl Ascorbate, Tocopherol, Tocopheryl Acetate, Steareth-21, Panthenol, Retinyl Palmitate, Cyclodextrin, Hexanoyl Dipeptide-3, Norleucine Acetate, Centella Asiatica Extract, Lycium Barbarum Fruit Extract, Rh-oligopeptide-1 (Egf), Rh-polypeptide-1 (Bfgf), Copper Tripeptide-1, Dimethicone/Vinyl Dimethicone Crosspolymer, Peg-12 Dimethicone Crosspolymer, Sodium Polyacrylate, Carbomer, Xanthan Gum, Isohexadecane, Polysorbate 60, Butylene Glycol, Arctostaphylos Uva Ursi Leaf Extract, Mitracarpus Scaber Extract, Superoxide Dismutase (Sod), Saccharomyces Ferment Lysate Filtrate, Sodium Hyaluronate, Hydrolyzed Vegetable Protein, Adenosine Triphosphate (Atp), Yeast Polysaccharides, Acetyl Tyrosine, Proline, Oleyl Alcohol, Dioscorea Villosa (Wild Yam) Root Extract, Glycine Soja (Soybean) Sterols, Perfluorodecalin, Ceramide 3, Rhodochrosite Extract, Hematite Extract, Phaeodactylum Tricornutum Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Sodium Pca, Trehalose, Allantoin, Peg-32, Hydroxyethylcellulose, Olea Europaea (Olive) Fruit Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Steareth-2, Peg-30 Dipolyhydroxystearate, Alcohol,Disodium Edta, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol.