Three of the best anti-aging serums


Looking for a supercharged serum that tackles fine lines and wrinkles, dark spots and dullness? Type “anti-aging serum” into your search engine and the resulting list seems endless. Searching for that perfect product often turns out to be a total waste of (face)time — and, worse, money. That’s where Truth In Aging reviewers come in. Our community slathers through serums to determine the ones that deliver visible results, consistently, so you don’t have to. We recently polled our members to determine which serums outshine (without leaving shine) the rest. Packed with plumping peptides, powerful antioxidants and advanced technologies like growth factors, this star-studded list is seriously impressive.

The community has spoken... Scroll through the list of best anti-aging serums, according to Truth In Aging reviewers.  

Your Best Face Restore Night Treatment Serum ($130 in the shop)

Packed with line-smoothing peptides and brightening agents, this serum restores the look of youthful skin while you sleep.

Reviewer’s take: “Your Best Face Restore is my favorite serum because it works just as the name says — it restores. When I continuously use this product my skin looks amazing. It evens out my skin tone, brightens my complexion and provides just enough hydration. I love that my skin looks and feels refreshed and healthy when I wake up.”                        

ClarityRx Get Fit Peptide Serum ($105.75 in the shop)   

Using a powerful combination of six age-reversing peptides, this no-frills formula radically reduces wrinkles while improving skin texture and tone.

Reviewer’s take:  “Other products and makeup layer over it easily without pilling. The best part is that my wrinkles and little mouth lines are seriously less noticeable!”

AQ Skin Solutions Eye Serum ($99; coming back to the shop soon)                                                 

Powered by growth factor technology and Matrixyl 3000, this eye treatment activates the skin’s natural regeneration capabilities to help minimize crow’s feet, dark circles and sagging eyelids.

Reviewer’s take: “AQ’s serum for the eye area is my favorite. It has a nice texture that wears well under makeup. I think it has made my eyes younger looking, plus it does great things for my lashes. Many people guess my age to be nearly two decades younger!”

Deciem NIOD Copper Amino Isolate Serum 1% ($60 in the shop)             

This champ contains a high concentration of pure copper tripeptide-1, which is known to assist in wrinkle reduction and collagen formation.

Reviewer’s take: “Copper Amino Isolate 1% turns my 42-year-old, rough-like-leather skin to soft and smooth overnight. I'm on my third bottle and have continued to see results, including the fading of acne scars and firming all around.”

MitoQ Moisturizing Anti-Aging Serum ($119; coming back to the shop soon)

The innovative anti-aging formula supports healthy skin cell function by directly targeting the cell’s mitochondria, resulting in less lines and renewed radiance.

Reviewer’s take: “The MitoQ serum remains my go-to and favorite. It offers light hydration and makes my skin smooth and glowing.”            

Sciote Omni Phyto-Cell Serum ($130 in the shop)

In addition to restoring phyto stem cells, Sciote uses Matrixyl 3000 to tighten and lift and a blend of amino acids to hydrate and strengthen the skin matrix.

Reviewer’s take: “It plumps the face, fills in fine lines and gives skin a nice glow.”    

E'shee Clinical Esthetic Elixir of Life KI Therapy Serum ($189 in the shop)

E’shee combines growth factors (FGF 1 peptide) and Far Infrared Ceramic Powder (cFIR) in this cult-fave formula to firm, smooth, reduce redness and restore vitality.

Reviewer’s take: “I love the way it hydrates without blocking pores and the natural glow it gives my skin.”

Medik8 Firewall ($145; coming back to the shop soon)

The dual-chamber pump, which maximizes the potency of the product, houses powerful anti-agers and antioxidants, including as copper peptides, Matrixyl 3000, Lipochroman-6 and niacinamide.

Reviewer’s take: “I adore Medik8 Firewall for the dual performance perspective. I am able to combat the aging process from different aspects.”                                                  

ExPürtise Effective Anti-Aging Eye Serum ($65 in the shop)

A generous dose of peptides relax wrinkles over time while sodium hyaluronate hydrates and vitamin K lessens the look of dark circles on the spot.

Reviewer’s take: “This is really making a difference on my eyelids — they are noticeably tighter!”

ReLuma Skin Illuminating Anti-Aging Serum ($145 in the shop)                

This five-star serum boasts a blend of 387 human growth factors, along with matrix proteins, to reduce inflammation, diminish wrinkles, tighten skin and restore luminosity.

Reviewer’s take: “ReLuma is hands down my favorite for treating my eleven lines, lip lines and the crinkles around my eyes.”  

ExPürtise Effective Anti-Aging Face Serum ($120 in the shop)                                                   

Matrixyl 3000, Matrixyl Synthe'6, apple stem cells and epidermal growth factors restore collagen and elastin fibroblasts for a smoother and more lifted appearance.

Reviewer’s take: “Effective Anti-Aging Face serum is a winner in my book, because it is gentle yet delivers real results.”