truactiv tritoxin

Reviewed by Marta on November 9, 2015


When you buy a TruActivs product, your money certainly isn’t going into the packaging. The company boasts that it has its own privately-owned lab and that they invest in ensuring that their products have a high concentration of actives rather than fancy marketing or components. TruActivs TriToxin ($220), which I have been testing for about six weeks, is plastic, utilitarian and proud of it. So does the focus on ingredients pay off?

The short answer is yes, TriToxin, has done a good job of softening crow’s feet and forehead lines. I decided to focus on these areas since I have been neglecting them of late and really thought I was beginning to see a worsening. TriToxin has certainly reversed this and I have been slowly but surely seen cumulative effects over a month and a half.

The formula takes some novel approaches and with three types of venom — bee, snail and “snake” — is not for the faint hearted. There’s a lot going on in this serum, including growth factors, copper and grape stem cells, but I’ll start by discussing snail venom since that was a new one for me.

I didn’t even know snails had venom. I don’t think the garden variety do, we are talking one genus of snail, cone snails (sea snails), which is worth Googling as it is a flamboyantly patterned creature. It recently got the attention of medical science when it was discovered that it’s venom could be used as a powerful painkiller. Cone snail venom is packed with peptides (as much as 100 different peptides in every snail) and in small amounts these neurotoxins prevent muscle contractions.

Bee venom is better known to me as an anti-aging active. Apitoxin acts as a strong anti-inflammatory and antiseptic. One researcher claimed that apitoxin "deserves no less attention of the medical profession than antibiotics of fungal and bacterial origin." It’s 18 active compounds include peptides and hyaluronidase.

The third venom is Syn-Ake isn’t really a snake venom, but a combination of neuropetides that mimic the peptide in vipers called Waglerin-1 to relax muscles and minimize — at least in theory — expression lines. 

It is worth noting that you shouldn’t feel anything with these actives. There is no stinging sensation from bee venom and there is no hint that the facial muscle movement is even slightly impaired. Nor are there any adverse effects from one of the other bee-related actives, royal jelly. This is secreted by honeybees to feed and nurture queen bees. It contains amino acids, fatty acids, antioxidants, proteins, minerals and vitamins (including B1, B2, B5 and B6). Its high water content in addition to its fatty acid content make it an effective moisturizer. Its silicon content can bolster collagen production, supporting skin renewal and firming skin. Royal jelly also contains high amounts of antioxidants, which help combat free radical damage.

Although TruActivs makes a big deal of the venomous sting in TriToxin’s tail, there is a roster of other heavy hitters here. A very welcome inclusion is sH-oligopeptide-1, an epidermal growth factor. There are two forms of plant stem cells, grape and alpine rose. Pseudoalteromonas ferment extract is a peptide sourced from a bacteria that can boost collagen, according to research. Also worth a call out are zinc and copper gluonate.

This unscented cream is definitely active intense. There are few if any fillers and the usual suspects in the preservative department. With visible results in six weeks, TriToxin is my kind of poison. There is just one consideration, however, and that is that there is a price to be paid for such a star-studded cast. I’d really like to know if others would find TriToxin worth a $220 price tag and so we’ll be putting one up for a “Test with Marta” soon!