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Vespro Regeniskin Regeneration Cream- reviewed and recommended

October 15, 2012 Reviewed by JulieKay 15 Comments

A couple months ago, Junko asked me in comments to my Challenged by Hands article what I was using as my current hand regimen; if I’d found anything new that was working better than what I’d found before. We discovered we were both using the same product- ZO Skin Health’s Oraser Day and Night Hand Care. We also agreed that although there was some improvement in both our hands; I could say (after using it for more than 3 months) the improvements had leveled off, and if I stopped dutiful application even for a couple days, immediate crepeness washed over the backs of my hands as predictably as a high tide. To date, however, ZO Skin for Hands is the best hand treatment I’ve found, and I’m still using it.

After Junko’s inquiry, I was motivated to do some research and went to Google, “What is the best hand cream?” This led to a majority of biased marketing lists which lent little to my research needs. One list, however, pointed out a list compiled of creams all containing EGFs, HGF or Human Growth Factors. Knowing some of Marta’s favorites are based on human growth factors as well as other luxurious potions I’ve read about, my first reaction was: “too expensive,” but also knowing (trusting) Marta knows her stuff, I began reading through the list. Expensive proved mostly true, at least for my budget- especially for a potion I would be purchasing for test purposes, until I got to a product called Regeniskin.

I purchased Regeniskin that same day, and it arrived within a week. The jar is an “old game” open to the air, no bells or whistles, jar. I paid $29.95 for 50ml/1.7oz, however, I just put in a reorder, and the cost now has gone up to $39.95. There is a discount if you buy 3 or more jars.

I’ve used Regeniskin for approximately 2 months at least twice a day. The texture is light, the fragrance slightly lemony, a small dab on the back of each hand is absorbed completely in seconds and leaves your skin feeling slightly taut. I immediately apply day or night ZO Skin Oraser or even Amala rejuvenating hand cream.  I think any cream or lotion you like would suffice on top of Regeniskin.

Before I began using Regeniskin, the skin of my hands was incredibly thin and creped. Incredibly! When it began to thicken I was too nervous to believe it could be true, but as the weeks compiled, I’ve had to admit it is true. Before using Regeniskin, the skin of my hands wouldn’t hold moisture from lotions; now when I’m done applying Regeniskin plus hand lotion, my hands feel like butter. As an illustration I’d say my hands look a decade younger; I’m not exaggerating.

I love the results I’m getting from Regeniskin on my hands, and I recommend this cream. I’m curious how it would do on the face and neck. As I’ve purchased my second jar, I may venture upwards.

Ingredients: Deionized water, bioferm complex (jopboa, saponaria yucca, rosemary, chamolime, comfrey, arnica, juniper, horsetail, protein growth factor, glyceryl monostearate, stearic acid, octyl salicylte, aloe vera, almond oil, caprylic/capric triglyceride, methylparaben, propylparaben, sweet orange oil.

  • May 25, 2013

    by Terri

    Hi Carol.
    I'm not a TIA rep just a person who turns to TIA for honest opinions and truth about products and/or ingredients and happened to see you inquiry while browsing. Reginskin is not a product carried in the TIA shop but that does not mean it is not a good product. As you've seen from what you've read several people have experienced great results. You can copy and paste the following link to order from a company called VesPro. Hope this helps.

  • May 25, 2013

    by Marta

    Hi Carol, we don't sell this particular cream. But you can buy it from Vespro.

  • May 25, 2013

    by carol


    I have tried every way I can think of to order this product from TIA but cannot get to it. Can you help?

  • December 13, 2011

    by Julie Kay

    Amanda- glad you like it. I keep my jar of Regeniskin next to my bedside. I use it nightly on my hands (with a good hand lotion). If in the mood, my arms and legs get a good lather; as well as my forehead. I'm also liable to put a dab where marionette lines develop if I feel like it and (yes, Junko) on my neck. It all depends on "if I feel like it." The heavy hitters for my face and neck still reside in the bathroom. ~jk

  • December 13, 2011

    by Amanda

    I've been really pleased with Regeniskin too. It's the only thing I've found that makes my hands look well-moisturized, and there may have been some fading of sun spots although I couldn't swear to it (no before photos either, alas). Thanks for reconfirming my positive opinion. I do a quick google every now and then to make sure no one's discovered some horrible side effect after several years' use. Growth factors sound kind of intimidating!

  • December 1, 2011

    by Jaysie

    Julie - I went to the VesPro web site and saw that they list many other growth factors besides the protein GF that's in the BioFerm Complex. For anyone else who is curious, their ingredient disclosure looks like this:

    "RegeniskinTM formula, for the first time ever, combines these top ingredients: The biological activity of these growth factors is verified by University of Kansas studies.

    Active Ingredients
    stabilized Epidermal Growth Factors (EGF)
    stabilized Platelet derived Growth Factor(PDGF)
    stabilized Transforming Growth Factors (TGF)
    stabilized Fibroblast Growth Factors (FGF)

    Other Natural Ingredients Protein Growth Factor, Bio-Ferm Herbal Complex (includes Jojoba, Saponaria, Yucca, Rosemary, Chamomile, Comfrey, Arnica, Juniper and Horsetail), Glyceryl Monostearate, Stearic Acid, Octyl Salicylate (sunscreen), Aloe Vera, Almond Oil, Caprylic/Capric Triglyceride, Deionized Water, Methylparaben, Propylparaben, Sweet Orange Oil (natural Fragrance)."

    They also caution anyone who has a skin sensitivity to dairy products. I wonder if all the growth factors are from cow's milk. From that leap, can you tell I'm not a scientist? :)

  • December 1, 2011

    by Julie Kay

    Jaysie, don't slap me upside the head, but I haven't a clue. The website has it all listed with semi impressive hoopla. I went with it for the other nasty ingredients it didn't include. It acts like a serum in consistency; needs a moisturizer to top it off. I have grown quite fond of Regeniskin. ~jk

  • December 1, 2011

    by Jaysie

    Hi Julie - Sounds like a hand cream I should try! The growth factor in the ingredient list has a pretty generic description. Do you happen to know the source of the growth factor...animal? plant?

  • November 22, 2011

    by Marta

    I've been using this on my hands as well. I haven't had quite the dramatic results that Julie has, but I do find it helpful. Moisturizer with it is a must though, as I find it too lightweight and not especially hydrating. But is it good for the price - yes, indeed.

  • October 18, 2011

    by Penny Grace

    I've been searching for something for my poor "veiny" and wrinkled" hands for a long long time. This sounds very promising. I can't wait to hear what your take is on this, Marta.


  • October 16, 2011

    by JulieK

    Junko- EXACTLY! Manufacturers just don't seem to get that the hands need the "big guns" (maybe bigger) as well the face and neck do. Most hand creams lack the "get-go" cosmetic actives needed for really aging hands. I'm sure, as I did, that's why you snapped up Zo, as it has Matrixyl 3000. Yet alone, even Zo wasn't enough for what aging hands need. They're demanding, but look how we often treat them!

    Dennis- I know, I know- I so wish I'd taken a before in this case. I've taken befores before, only to believe (in the after) it was a waste of vanity.

    Marta- I was hoping you'd give this your nod. I'm eager to hear how you get on.

    Peace ~jk

  • October 15, 2011

    by Junko

    Julie * Looks like a wonderful find! To me, handcreams often do not have enough repair actives in them to do anything other than moisturize. More is needed which is why I also bought ZO. I am fascinated/obsessed with EGF's and you've found an economical one. I hope you'll try it on your neck and face too!

  • October 15, 2011

    by Dennis

    Awesome Julie! but where are the before and afters? ;)

  • October 15, 2011

    by Jen E

    Sounds like a great product...maybe TIA shop worthy! I'm currently testing the Heaven Bee Venom Mask & have been including the back of my hands in the testing areas...and I am liking it! My hands appear less veiny now, if that makes sense?

  • October 15, 2011

    by Marta

    Thank you for the review Julie. This product looks so interesting that I have ordered it. I'll let you know how I get on.

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