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YNS Medspa Intensive Peptide Complex Radiance

Reviewed by Marta July 1, 2010 43 Comments
YNS Medspa Intensive Peptide Complex pretty much had me at hello with power peptides making up the first four ingredients (after HO2).  Skimming over the rest of the list I was willing to engage in a friendly conversation. And with the price at $65 we could be talking friendship.

Intensive Peptide Complex found me and the nice people there sent a sample so I can’t claim credit for tracking this one down. Behind YNS (which stands for Younger New Skin) are the Breusch sisters (Ann and Natasha) and with the help of Dr Mine Kurtay they seem to go for a mix of botanicals shot with some of the cutting edge laboratory grown actives. For example, another product of theirs has the recently introduced Renovage that is used by Osmotics and Your Best Face.

Intensive Peptide Complex Radiance majors on two neuropeptides Argireline and Pentapeptide-18 (which also goes by the name of Leuphasyl) that work by inhibiting the muscle movements that cause expression lines. Then there are collagen building Matrixyl 3000 and SYN-COLL. The (manufacturer’s) claims for Syn-Coll are eye-brow raising, to say the least. Collagen production is increased by 119% and the manufacturer says it will actually remove wrinkles. It is claimed that a 2.5% concentration of Syn-Coll outperforms Matrixyl (Matrixyl 3000’s sister peptide) at 10%.

L-proline is also a good inclusion. One-sixth of collagen, a major building block of skin (and its youthful appearance) is comprised of proline. According to research, Proline can break down protein to help create healthy cells and connective tissues, promoting firmer, glowing skin and reducing sagging, wrinkles and aging of skin due to sun exposure.

With yeast and milk protein, plus sodium hyaluronate, this potion may indeed prove to be “intensive”.  There are useful botanicals as well, such as butcher’s broom and horse chestnut, which contain chemicals that attach to and strengthen blood vessels, and soothing calendula.

YNS has to be commended for what it has left out too. There isn’t a silicone in site and, apart from phenoxyethanol and butylene glycol, there is nothing not to like. I’ll be testing this over the coming weeks and will let you know how it works out.


Aqua (water), Acetyl-Hexapeptide -3 (Argireline®), Pentapeptide-18 (Leuphasyl®), Palmitoyl Tetrapeptide-3 and Palmitoyl Tetrapeptide-7 (Matrixyl® 3000), Palmitoyl Tripeptide-5 (SYN®-COLL), Sodium Hyaluronate (humectant), Sodium PCA (humectant), Aloe Barbadensis (emollient), Panthenol (skin conditioning), Simmondsia Chinensis Oil (jojoba oil emollient), Butyrospermum Parkii Butter (shea butter emollient), Acetylated Cetyl Hydroxyprolinate (L-proline), Hydrolyzed Milk Protein (skin conditioning), Hydrolyzed Yeast Protein (skin conditioning), Coco-Caprylate/Caprate (emollient), Caprylic/Capric Triglyceride (emollient), Cetearyl Alcohol (emollient), Cetearyl Glucoside (emulsifying), Ruscus Aculeatus Extract (butcherbroom soothing), Cellulose Gum (visocity controlling), Glycerin (humectant), Allantoin (soothing), Centella Asiatica Extract (leaves of the hydrocotyl soothing), Calendula Officinalis Oil (emollient), Cucumus Sativa Oil (cucumber oil emollient), Aesculus Hippocastanum Extract (horse chestnut seed astringent), Fructose (humectant), Gluconolactone (humectant), Benzyl PCA Phenoxyethanol. Butylene Glycol (preservative).
  • April 18, 2016

    by Barbara

    A friend told my about this company. After checking out their website, I thought I would give their products a try. At my age (68), not sure what to expect. I have been an Este Lauder user for years. I have now been using the products for six weeks and I can definitely tell a difference in the appearance of my skin and the feel. My eyes look brighter without that extra puffiness. I feel better about myself. I especially like that there are just three easy products to use. Nothing complicated. I plan to continue using these products. Couldn't be happier about the results. Thank you YNS

  • January 17, 2013

    by Patrice Pompa

    I love this product and have been using it for over a year! The consistency is great and it goes on easily. I stopped for the past 3 months to try something different, but am going back to Radiance. I would highly recommend it!

  • November 12, 2010

    by Inga

    Found this website by coincidence! I've used Radiance and its complementary product, yNs A Cell-Tight, for about 4 years. It is by far the most effective regimen ever. No one believes my age (I'll only see 60 in my rear-view mirror!). My skin is wrinkle-free, smooth and radiant. UV-light damage is practically gone, something micro-dermabrasion and more aggressive treatments did not affect. For the first time ever I'm comfortable without foundation, but living in Florida I use it (yNs mineral-based foundation) to protect my skin. I strongly endorse this product for anyone who wants measurable results. Afford-ability is another plus, but I spent more on less effective products.

  • September 28, 2010

    by Kari

    p.s. This is my FIRST foray into trying a "wrinkle reducing" or "skin repairing" product. I have been a faithful user of Origins Dr. Weil "magic mushroom" (or whatever mushroom it is anyway!) line and it has kept my skin soft and nonirritated (which is what it is intended to do--helps people with rosascea (sp?) for example). I just have finally decided that I've "had enough" of this constant increase in wrinkling and sagging, so, after finding this website and reviewing several blogs/products, took a chance on the yNs product.

    I am hopeful! Good luck to everyone!

  • September 28, 2010

    by Kari

    I got the 10 day test set. I am 36. Skin problems: large pores to nose and chin, easy breakouts with any new products, forehead wrinkles, crow's feet, parentheses around my mouth from years of smoking (but I quit!) and performing in theater. Wrinkles were intensified by the need for "over expression" while on stage to convey emotion to the rear of the theater (after college, I am an emergency/critical care nurse--yes, that was my major..after I realized i was the "little guppy" in the ocean of the real world of opera performance as opposed to the "big fish in the puddle of high school" HA!!).
    Typically ANY change in facial care products makes me break out immediately--these products HAVE NOT.
    Now, by following the directions, I have noticed that the night care products still feel "sticky" on my face after waking, but I don't know if this is normal or not.
    I have been using the product for five days, and a little goes a long way--I will probably have more than enough product to last beyond the "ten day trial" amount.
    I have noticed that my hereditary undereye circles are DEFINITELY starting to lighten and my skin does seem a bit brighter. After high school in 1992 I've normally gone without foundation unless I am in a super cold, drying environment--like when we visit KY or PA for the holidays (we live in TX). My skin, despite having wrinkles since my mid20's (was a 15 year smoker until I quit 11 years ago), has always been smooth with the exception of breakouts, but I've always had large pores. Now my skin is starting to feel softer AND smoother but I haven't noticed a pore size difference yet. However, despite not knowing what the long term effects of fixing my crow's feet and the "parentheses" around my mouth will be with this product, it does certainly appear promising!
    I may just go ahead and order another test kit for my husband...then abscond into the bathroom and lock the door!

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