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ZO Skin Health Ossential Advanced Radical Night Repair Review

is a Solution for:
Acne, Age Spots, Fine Lines, Large Pores, Wrinkles
ZO Skin Health Ossential Advanced Radical Night Repair
June 23, 2017 Reviewed by TIA Community Member 1 Comment
TRU Rating
Formulated with a 1 percent retinol concentration, this cream proved to be too harsh with little payoff


Microencapsulated retinol stimulates epidermal renewal


May cause irritation; contains some undesirable ingredients

By Lorraine G.

I have been testing the Zo Skin Health Ossential Advanced Radical Night Repair ($170) for the past 30 days. This product, according to the company’s website, has multiple benefits, including maximum anti-aging results, skin brightness and a more even tone, antioxidant protection and the calming of irritation. I’m around 50 years old, so at first glance, this seemed to be a welcomed addition to my anti-aging arsenal.

This product contains a stabilized, whopping 1 percent microencapsulated retinol, which stimulates skin renewal and collagen production. Vitamins C, E, and A and plant stem cells provide a hefty dose of antioxidants and anti-aging properties. Furthermore, this product contains Sichuan pepper, sunflower seed oil, and rosemary leaf extract, which according to the product website, make up an anti-irritant complex. Finally, glycerin and plukenetia volubilis seed oil provide hydration and help to restore the skin barrier.

While this product has a host of beneficial ingredients, it also has a few undesirables. Cyclotetrasiloxane poses a moderate overall hazard and has a low to medium risk on developmental and reproductive toxicity, according to the EWG. In addition, phenoxyethanol lies in the top third of the ingredient list, which is a known preservative that can be an irritant to the eyes and skin. So, this product probably would not suit any purists out there.

My response to using this product is mixed. When I first started using it twice a week, my skin felt quite sore and slightly irritated. It started to peel within a few days of use, which can be expected with some strong retinol products. However, for me, I was never able to increase the use to every other day as the directions stated because I found the product to be too irritating. It also states not to use any other product on top of this one at night. I followed these guidelines, but found that my skin felt very dry in the mornings and was not at all comfortable.

Let me note that I have used prescription Retin A products before with a 0.02 percent concentration and have managed to use these products every other day, so what I can surmise from this is that this particular product is very strong and definitely comparable to a prescription strength product. So, while this product was too strong for my skin, which leans toward the dry and slightly-sensitive side, it may be fine for someone who can tolerate stronger, more potent products.

This product does have a host of beneficial anti-aging ingredients and offers a high concentration of over-the-counter retinol for someone who can better tolerate it. However, if you have sensitive skin that is on the drier side, or you are a purist for product ingredients, then this product may not be for you.

  • August 4, 2017

    by Love this product and the entire line!

    This product is amazing! I use it every night. This product will change your skin if used properly. You must be consulted by a provider due to the strength of this product. It exfoliates alll the dry skin, leaving you with soft beautiful skin. It tricks your own body into hydrating your skin from the inside. There are other products in the line to help calm the skin during the acclimation process.

    I am 53 and have no wrinkles, I have been using this for about 5 years. Works like nothing else! Buy, this from a licensed provider and get a full treatment plan.

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