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ZO Skin Health Ossential Growth Factor Serum Plus Review

ZO Skin Health Ossential Growth Factor Serum Plus
May 22, 2017 Reviewed by Marta 1 Comment
TRU Rating
The good does not outweigh the bad in this deceiving serum


Contains an interesting anti-aging ingredient


Formulated with harsh ingredients; no skin improvements

This was a case of wishful thinking in flagrant denial of the facts. Throughout my entire test of ZO Skin Health Ossential Growth Factor Serum Plus ($148), I was convincing myself that there were actual growth factors in it. There isn’t, but the self-deception had the advantage of keeping me committed to my trial in the face of disappointment. This serum had no effect whatsoever throughout my 30-day trial. It had no impact on wrinkles, it did not make my skin firmer, it didn’t even make my skin more hydrated. It struck me that ZO needs two more letters to spell zero.

ZO Skin Health Ossential Growth Factor Serum Plus, despite its name, does not have growth factors. It does have something that the brand calls ZPRO. I don’t know what combination of the ingredients listed this refers to. More recognizable and certainly welcome are plant stem cells and ginseng root ferment. With a nod to what have become anti-aging stalwarts, there is retinol, moisturizing phospholipids and a peptide that inhibits expression lines. All good, but not great.

The most interesting ingredient is adenosine triphosphate, the main energy source for the majority of cellular and muscular functions. Living things use ATP like a battery, storing and using energy as needed. Boosting ATP is an important factor in anti-aging.

Although the packaging is sleek and modern, and the serum itself is an easily absorbed, non-greasy gel, this product makes me think of the department store creams of yesteryear. Before you get to any of the interesting ingredients, there are plenty of silicones, glycols, PEGs and preservatives to get past. Then, after the abovementioned ATP, they all start up again. The good definitely doesn’t outweigh the bad, so I’m not shocked by the results — or lack thereof.


  • December 7, 2017

    by Jill

    I love this product!! In all fairness 30 days trial is not long enough. I have been using for several years and my skin is better than Its ever been. Love the skin you're in with ZO

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